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Protein

Ribosomal RNA large subunit methyltransferase G

Gene

rlmG_2

Organism
Enterobacter cloacae
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.UniRule annotationSAAS annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(1835) in 23S rRNA = S-adenosyl-L-homocysteine + N2-methylguanine(1835) in 23S rRNA.UniRule annotationSAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionMethyltransferaseUniRule annotationSAAS annotationImported, Transferase
Biological processrRNA processingUniRule annotationSAAS annotation
LigandS-adenosyl-L-methionineUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA large subunit methyltransferase GUniRule annotationSAAS annotation (EC:2.1.1.174UniRule annotation)
Alternative name(s):
23S rRNA m2G1835 methyltransferaseUniRule annotation
rRNA (guanine-N(2)-)-methyltransferase RlmGUniRule annotation
Gene namesi
Name:rlmG_2Imported
Synonyms:rlmGUniRule annotation
ORF Names:SAMEA2273162_05457Imported
OrganismiEnterobacter cloacaeImported
Taxonomic identifieri550 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEnterobacterEnterobacter cloacae complex

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliA0A157WFW8
SMRiA0A157WFW8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini201 – 371MTSInterPro annotationAdd BLAST171

Sequence similaritiesi

Belongs to the methyltransferase superfamily. RlmG family.UniRule annotationSAAS annotation

Family and domain databases

HAMAPiMF_01859 23SrRNA_methyltr_G, 1 hit
InterProiView protein in InterPro
IPR002052 DNA_methylase_N6_adenine_CS
IPR017237 rRNA_m2G-MeTrfase_RsmD
IPR029063 SAM-dependent_MTases
IPR007848 Small_mtfrase_dom
PANTHERiPTHR18895:SF6 PTHR18895:SF6, 1 hit
PfamiView protein in Pfam
PF05175 MTS, 1 hit
PIRSFiPIRSF037565 RRNA_m2G_Mtase_RsmD_prd, 1 hit
SUPFAMiSSF53335 SSF53335, 2 hits
PROSITEiView protein in PROSITE
PS00092 N6_MTASE, 1 hit

Sequencei

Sequence statusi: Complete.

A0A157WFW8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPLFATPFAQ LDLVRQPEQD GEPLQAFDAA DEYLLNQLHE RGVTAQCRVL
60 70 80 90 100
VLNDAFGALA ASLAPHVQVT SSGDSHLGFL ALRKNLARNG LDLGSVRFVP
110 120 130 140 150
ASETAVGPFD HVLVKVPKTL ALLEEQLIRL HGQLAPGAQV VAAGMVKHLP
160 170 180 190 200
RAAGDLLERY IGPMHASLAV KKARLLIAEA AERPQPRSPY PTRYRLEQPP
210 220 230 240 250
LTLLNHANVF CREGLDIGTR AFLPHLPRSL GALRAADLGC GNGVLGIAYA
260 270 280 290 300
LLNPQAELTL VDESYMAVQS ARENWRAALG ERPATFRADD GLAGQAAGSL
310 320 330 340 350
DLVLCNPPFH QQQVVGDFLA WRMFLQARDA LAAGGELWIV GNRHLGYHAK
360 370
LKRLFRGVEQ VAANPKFVIL KAGK
Length:374
Mass (Da):40,506
Last modified:June 8, 2016 - v1
Checksum:iC7C6DAF03D709AFF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FKIY01000059 Genomic DNA Translation: SAJ29305.1

Similar proteinsi

Entry informationi

Entry nameiA0A157WFW8_ENTCL
AccessioniPrimary (citable) accession number: A0A157WFW8
Entry historyiIntegrated into UniProtKB/TrEMBL: June 8, 2016
Last sequence update: June 8, 2016
Last modified: October 25, 2017
This is version 9 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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