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Protein

Transcription termination/antitermination protein NusG

Gene

nusG

Organism
Yersinia pestis
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination.UniRule annotation

GO - Biological processi

Keywordsi

Biological processTranscription, Transcription antiterminationUniRule annotationSAAS annotation, Transcription regulation, Transcription terminationUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription termination/antitermination protein NusGUniRule annotationSAAS annotation
Gene namesi
Name:nusGUniRule annotationImported
ORF Names:AU254_20415Imported, AVO31_20040Imported
OrganismiYersinia pestisImported
Taxonomic identifieri632 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeYersinia

Interactioni

Subunit structurei

Monomer. Interacts with the transcription termination factor Rho and with RNA polymerase.UniRule annotation

Structurei

3D structure databases

SMRiA0A154S8S8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 115NGNInterPro annotationAdd BLAST110
Domaini127 – 154KOWInterPro annotationAdd BLAST28

Sequence similaritiesi

Belongs to the NusG family.UniRule annotationSAAS annotation

Phylogenomic databases

KOiK02601.

Family and domain databases

Gene3Di2.30.30.30. 1 hit.
3.30.70.940. 1 hit.
HAMAPiMF_00948. NusG. 1 hit.
InterProiView protein in InterPro
IPR005824. KOW.
IPR006645. NGN_dom.
IPR036735. NGN_dom_sf.
IPR014722. Rib_L2_dom2.
IPR001062. Transcrpt_antiterm_NusG.
IPR015869. Transcrpt_antiterm_NusG_bac_CS.
IPR008991. Translation_prot_SH3-like_sf.
PANTHERiPTHR30265:SF2. PTHR30265:SF2. 1 hit.
PfamiView protein in Pfam
PF00467. KOW. 1 hit.
PF02357. NusG. 1 hit.
PRINTSiPR00338. NUSGTNSCPFCT.
SMARTiView protein in SMART
SM00739. KOW. 1 hit.
SM00738. NGN. 1 hit.
SUPFAMiSSF50104. SSF50104. 1 hit.
SSF82679. SSF82679. 1 hit.
TIGRFAMsiTIGR00922. nusG. 1 hit.
PROSITEiView protein in PROSITE
PS01014. NUSG. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A154S8S8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEAPKKRWY VVQAFSGFEG RVAQSLREHI KLHDMEELFG EVMVPTEEVV
60 70 80 90 100
EIRGGQRRKS ERKFFPGYVL VQMVMNDASW HLVRSVPRVM GFIGGTSDRP
110 120 130 140 150
APISDKEVDA IMNRLQQVGD KPRPKTLFEP GELVRVSDGP FADFNGVVEE
160 170 180
VDYEKSRLKV SVSIFGRATP VELDFSQVEK G
Length:181
Mass (Da):20,514
Last modified:June 8, 2016 - v1
Checksum:iC078FF359DFE1826
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LPTX01000223 Genomic DNA. Translation: KYP00004.1.
LQAV01000193 Genomic DNA. Translation: KZC65093.1.
RefSeqiWP_002210671.1. NZ_LT605018.1.

Genome annotation databases

GeneIDi31914128.
KEGGiypj:CH55_3274.
ypl:CH46_1325.
ypv:BZ15_3974.
ypw:CH59_1676.
PATRICifig|632.151.peg.2486.

Similar proteinsi

Entry informationi

Entry nameiA0A154S8S8_YERPE
AccessioniPrimary (citable) accession number: A0A154S8S8
Entry historyiIntegrated into UniProtKB/TrEMBL: June 8, 2016
Last sequence update: June 8, 2016
Last modified: November 22, 2017
This is version 16 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported