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Protein

Sodium/potassium-transporting ATPase subunit alpha

Gene

ATP1A1

Organism
Alligator mississippiensis (American alligator)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotation
Biological processIon transport, Potassium transportUniRule annotation, Transport
LigandATP-bindingUniRule annotationSAAS annotation, Metal-bindingUniRule annotation, Nucleotide-binding, Potassium

Names & Taxonomyi

Protein namesi
Recommended name:
Sodium/potassium-transporting ATPase subunit alphaUniRule annotation (EC:3.6.3.-UniRule annotation)
Gene namesi
Name:ATP1A1Imported
ORF Names:Y1Q_0015373Imported
OrganismiAlligator mississippiensis (American alligator)Imported
Taxonomic identifieri8496 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaCrocodyliaAlligatoridaeAlligatorinaeAlligator
Proteomesi
  • UP000050525 Componenti: Unassembled WGS sequence

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei100 – 122HelicalUniRule annotationAdd BLAST23
Transmembranei134 – 153HelicalUniRule annotationAdd BLAST20
Transmembranei295 – 319HelicalUniRule annotationAdd BLAST25
Transmembranei325 – 348HelicalUniRule annotationAdd BLAST24
Transmembranei856 – 877HelicalUniRule annotationAdd BLAST22
Transmembranei916 – 935HelicalUniRule annotationAdd BLAST20
Transmembranei956 – 973HelicalUniRule annotationAdd BLAST18
Transmembranei988 – 1004HelicalUniRule annotationAdd BLAST17

Keywords - Cellular componenti

Membrane

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini46 – 120Cation_ATPase_NInterPro annotationAdd BLAST75

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili22 – 49Sequence analysisAdd BLAST28

Sequence similaritiesi

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. [View classification]UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Family and domain databases

CDDicd02608. P-type_ATPase_Na-K_like. 1 hit.
Gene3Di3.40.1110.10. 2 hits.
InterProiView protein in InterPro
IPR006068. ATPase_P-typ_cation-transptr_C.
IPR004014. ATPase_P-typ_cation-transptr_N.
IPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR023298. ATPase_P-typ_TM_dom.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR036412. HAD-like_sf.
IPR005775. P-type_ATPase_IIC.
IPR001757. P_typ_ATPase.
PfamiView protein in Pfam
PF00689. Cation_ATPase_C. 1 hit.
PF00690. Cation_ATPase_N. 1 hit.
SMARTiView protein in SMART
SM00831. Cation_ATPase_N. 1 hit.
SUPFAMiSSF56784. SSF56784. 3 hits.
SSF81653. SSF81653. 1 hit.
SSF81660. SSF81660. 1 hit.
SSF81665. SSF81665. 3 hits.
TIGRFAMsiTIGR01106. ATPase-IIC_X-K. 1 hit.
TIGR01494. ATPase_P-type. 2 hits.
PROSITEiView protein in PROSITE
PS00154. ATPASE_E1_E2. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A151P2S2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPLLWGWGVQ AGREYSPAAT TSENGGGKKK QKEKELDELK KEVNLNDHRL
60 70 80 90 100
SLDEVGRKYE VDLSRGLTNA RAAESLAQHG PNALTPPPTT PEWVKFCRQL
110 120 130 140 150
FGGFSILLWI GALLCFLAYS IQAVMEDESS NDNLYLGVVL AAVVIVTGCF
160 170 180 190 200
SYYQEAKSSK IMDSFKNMVP QQALVIREGE KIQINAENVV VGDLVEVKGG
210 220 230 240 250
DRVPADLRII SSHGCKVDNS SLTGESEPQT RSPEFTHENP LETRNICFFS
260 270 280 290 300
TNCVEGTARG IVIATGDRTV MGRIASLASG LEVGRTPIAM EIEHFIHIIT
310 320 330 340 350
GVAVFLGLSF FILSLILGYT WLEAVIFLIG IIVANVPEGL LATVTVCLTL
360 370 380 390 400
TAKRMARKNC LVKNLEAVET LGSTSTICSD KTGTLTQNRM TVAHMWFDNQ
410 420 430 440 450
IHEADTTEDQ SGATFDKRSP TWAALARIAG LCNRAVFKAG QENVSISKRD
460 470 480 490 500
TAGDASESAL LKCIQLSCGS VKKMRDKNPK VTEIPFNSTN KYQLSIHERE
510 520 530 540 550
DDPEGYILVM KGAPERILDR CSTILLQGQE LPLDEEMRDA FQNAYLELGG
560 570 580 590 600
LGERVLGFCH LYLPNDQFPR GFKFDSDEVN FPITNLCFVG LMSMIDPPRA
610 620 630 640 650
AVPDAVGKCR SAGIKVIMVT GDHPITAKAI AKGVGIISEG NETVEDIAAR
660 670 680 690 700
LNIPVSQVNP REAKACVVHG SDLKDMTLEQ LDELLKNHTE IVFARTSPQQ
710 720 730 740 750
KLIIVEGCQR QGAIVAVTGD GVNDSPALKK ADIGIAMGIA GSDVSKQAAD
760 770 780 790 800
MILLDDNFAS IVTGVEEGRL IFDNLKKSIA YTLTSNIPEI TPFLLFIIAN
810 820 830 840 850
IPLPLGTVTI LCIDLGTDMV PAISLAYEAA ESDIMKRQPR NPKTDKLVNE
860 870 880 890 900
RLISMAYGQI GMIQALGGFF TYFVILAENG FLPCTLLGIR LDWDDRSTND
910 920 930 940 950
LEDSYGQEWT YEQRKVVEFT CHTAFFASIV VVQWADLIIC KTRRNSVFQQ
960 970 980 990 1000
GMKNKILIFG LLEETALAAF LSYCPGMGVA LRMYPLKVTW WFCAFPYSLL
1010 1020
IFVYDEVRKL IIRRYPGGWV EKETYY
Length:1,026
Mass (Da):113,016
Last modified:June 8, 2016 - v1
Checksum:i3CB6994B54846DD9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AKHW03001203 Genomic DNA. Translation: KYO43368.1.

Similar proteinsi

Entry informationi

Entry nameiA0A151P2S2_ALLMI
AccessioniPrimary (citable) accession number: A0A151P2S2
Entry historyiIntegrated into UniProtKB/TrEMBL: June 8, 2016
Last sequence update: June 8, 2016
Last modified: October 25, 2017
This is version 10 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported