Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Dephospho-CoA kinase

Gene

coaE

Organism
Gluconobacter oxydans (Gluconobacter suboxydans)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.UniRule annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

ATP + 3'-dephospho-CoA = ADP + CoA.UniRule annotation

Pathwayi: coenzyme A biosynthesis

This protein is involved in step 5 of the subpathway that synthesizes CoA from (R)-pantothenate.UniRule annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. Type III pantothenate kinase (coaX), Type III pantothenate kinase (coaX), Type III pantothenate kinase (coaX)
  2. Coenzyme A biosynthesis bifunctional protein CoaBC (AD929_16625), Coenzyme A biosynthesis bifunctional protein CoaBC (AD950_07645), Coenzyme A biosynthesis bifunctional protein CoaBC (AD934_12775)
  3. Coenzyme A biosynthesis bifunctional protein CoaBC (AD929_16625), Coenzyme A biosynthesis bifunctional protein CoaBC (AD950_07645), Coenzyme A biosynthesis bifunctional protein CoaBC (AD934_12775)
  4. Phosphopantetheine adenylyltransferase (coaD), Phosphopantetheine adenylyltransferase (coaD)
  5. Dephospho-CoA kinase (coaE), Dephospho-CoA kinase (coaE), Dephospho-CoA kinase (coaE)
This subpathway is part of the pathway coenzyme A biosynthesis, which is itself part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes CoA from (R)-pantothenate, the pathway coenzyme A biosynthesis and in Cofactor biosynthesis.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi8 – 15ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotationImported, Transferase
Biological processCoenzyme A biosynthesisUniRule annotation
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00241; UER00356

Names & Taxonomyi

Protein namesi
Recommended name:
Dephospho-CoA kinaseUniRule annotation (EC:2.7.1.24UniRule annotation)
Alternative name(s):
Dephosphocoenzyme A kinaseUniRule annotation
Gene namesi
Name:coaEUniRule annotation
ORF Names:AD950_06195Imported
OrganismiGluconobacter oxydans (Gluconobacter suboxydans)Imported
Taxonomic identifieri442 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesAcetobacteraceaeGluconobacter
Proteomesi
  • UP000075355 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the CoaE family.UniRule annotation

Family and domain databases

CDDicd02022 DPCK, 1 hit
HAMAPiMF_00376 Dephospho_CoA_kinase, 1 hit
InterProiView protein in InterPro
IPR001977 Depp_CoAkinase
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF01121 CoaE, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00152 TIGR00152, 1 hit
PROSITEiView protein in PROSITE
PS51219 DPCK, 1 hit

Sequencei

Sequence statusi: Complete.

A0A149UDN8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIIGLTGGM AAGKSTVAAL FRREGVPVFD ADACVRALQG ERGKALPLIG
60 70 80 90 100
QAFPGTVVAS RLDRAALREA VRGRPEALKR LEAIMHPLVR AERERFLKQC
110 120 130 140 150
RARHEPFCVL DIPLLMEIGE DRRCDVVVVA EAPMGTRLSR IRQRGRSGGR
160 170 180 190 200
MSVADAKGLL ARQMSDHERR RRADIVIRTG LSRGQAVRQV HALLHRLREA

S
Length:201
Mass (Da):22,239
Last modified:June 8, 2016 - v1
Checksum:iB852F4608B5A140E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LHZW01000051 Genomic DNA Translation: KXV65111.1
RefSeqiWP_062456633.1, NZ_LHZW01000051.1

Genome annotation databases

EnsemblBacteriaiKXV65111; KXV65111; AD950_06195
PATRICifig|442.10.peg.1157

Similar proteinsi

Entry informationi

Entry nameiA0A149UDN8_GLUOY
AccessioniPrimary (citable) accession number: A0A149UDN8
Entry historyiIntegrated into UniProtKB/TrEMBL: June 8, 2016
Last sequence update: June 8, 2016
Last modified: September 27, 2017
This is version 9 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health