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Protein

Polyribonucleotide nucleotidyltransferase

Gene

pnp

Organism
Trichococcus palustris
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.UniRule annotationSAAS annotation

Catalytic activityi

RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi490MagnesiumUniRule annotation1
Metal bindingi496MagnesiumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferaseUniRule annotationSAAS annotation, RNA-bindingUniRule annotationSAAS annotation, Transferase
LigandMagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Polyribonucleotide nucleotidyltransferaseUniRule annotation (EC:2.7.7.8UniRule annotation)
Alternative name(s):
Polynucleotide phosphorylaseUniRule annotation
Short name:
PNPaseUniRule annotation
Gene namesi
Name:pnpUniRule annotation
ORF Names:Tpal_323Imported
OrganismiTrichococcus palustrisImported
Taxonomic identifieri140314 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesCarnobacteriaceaeTrichococcus

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini626 – 694S1 motifInterPro annotationAdd BLAST69

Sequence similaritiesi

Belongs to the polyribonucleotide nucleotidyltransferase family.UniRule annotationSAAS annotation

Family and domain databases

Gene3Di3.30.1370.10. 1 hit.
3.30.230.70. 2 hits.
HAMAPiMF_01595. PNPase. 1 hit.
InterProiView protein in InterPro
IPR001247. ExoRNase_PH_dom1.
IPR015847. ExoRNase_PH_dom2.
IPR036345. ExoRNase_PH_dom2_sf.
IPR004087. KH_dom.
IPR004088. KH_dom_type_1.
IPR036612. KH_dom_type_1_sf.
IPR012340. NA-bd_OB-fold.
IPR012162. PNPase.
IPR027408. PNPase/RNase_PH_dom_sf.
IPR015848. PNPase_PH_RNA-bd_bac/org-type.
IPR036456. PNPase_PH_RNA-bd_sf.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR022967. S1_dom.
IPR003029. S1_domain.
PANTHERiPTHR11252. PTHR11252. 1 hit.
PfamiView protein in Pfam
PF00013. KH_1. 1 hit.
PF03726. PNPase. 1 hit.
PF01138. RNase_PH. 2 hits.
PF03725. RNase_PH_C. 2 hits.
PF00575. S1. 1 hit.
PIRSFiPIRSF005499. PNPase. 1 hit.
SMARTiView protein in SMART
SM00322. KH. 1 hit.
SM00316. S1. 1 hit.
SUPFAMiSSF46915. SSF46915. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF54211. SSF54211. 2 hits.
SSF54791. SSF54791. 1 hit.
SSF55666. SSF55666. 2 hits.
TIGRFAMsiTIGR03591. polynuc_phos. 1 hit.
PROSITEiView protein in PROSITE
PS50126. S1. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A143Y5V3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEKKVFQMD WAGRLLQVEI GQMAKQANGS VLVRYGDTVV LTAAVGSKEP
60 70 80 90 100
KDTDFFPLTV NYEEKMYSVG KIPGGFIKRE GRPSENATLT ARLIDRPIRP
110 120 130 140 150
MFQEGFRNEV QITNIVMSVE QDCSPELAAM FGSSLSLAIS DIPFAGPIAG
160 170 180 190 200
VNVGRVDGEY VLNPTPAQNE VSDIELTVAG SNDAINMVES SAAMVNEEDM
210 220 230 240 250
LGALMFGHRA IQELCAFQNK IVAEVGKEKM EIKLLALNPE LVAEINAAYA
260 270 280 290 300
EKMKAAILTE EKLAREDAIE AVKQEANEFF TEKYMDSETI VPVVKEIRQI
310 320 330 340 350
VENMEKDEVR SLITVDKIRP DGRKVDEIRP LASEVGLLPR VHGSGLFTRG
360 370 380 390 400
QTQALSACTL APLGEHQIID GLGLDESKRF IHHYNFPQFS VGSTGRAGSP
410 420 430 440 450
GRREIGHGAL GERALKQVIP TEAEFPYTIR LVAEVLESNG SSSQASICAG
460 470 480 490 500
TLALMDAGVP IKAPVAGIAM GLVMEGENYT VLTDIQGLED HLGDMDFKVA
510 520 530 540 550
GTSEGITALQ MDIKIQGITE QILTEALMQA KKARMEILAE LTNTIPAPRE
560 570 580 590 600
ELSQYAPKIE MMQIKPEKIK VVIGKGGDTI NSIIDETGVK IDIDQEGNVS
610 620 630 640 650
IASADAAMIA RAKQIIEELT REIKIGEIYE GTVKRIEKFG AFVEIAKGKD
660 670 680 690 700
GMVHISELAN ERVKEVEDVL AIGDKVKVKV IEIDRQGRIN LSRKALLNAD

EKGNAVQ
Length:707
Mass (Da):77,046
Last modified:June 8, 2016 - v1
Checksum:i9AAF5FEAB22C3476
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FJNE01000001 Genomic DNA. Translation: CZQ82475.1.

Similar proteinsi

Entry informationi

Entry nameiA0A143Y5V3_9LACT
AccessioniPrimary (citable) accession number: A0A143Y5V3
Entry historyiIntegrated into UniProtKB/TrEMBL: June 8, 2016
Last sequence update: June 8, 2016
Last modified: February 28, 2018
This is version 11 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)