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Protein
Submitted name:

Nuclear pore complex protein Nup98-Nup96

Gene

Nup98

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Enzyme and pathway databases

ReactomeiR-MMU-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
R-MMU-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript
R-MMU-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein
R-MMU-191859 snRNP Assembly
R-MMU-2467813 Separation of Sister Chromatids
R-MMU-2500257 Resolution of Sister Chromatid Cohesion
R-MMU-3108214 SUMOylation of DNA damage response and repair proteins
R-MMU-3301854 Nuclear Pore Complex (NPC) Disassembly
R-MMU-3371453 Regulation of HSF1-mediated heat shock response
R-MMU-4551638 SUMOylation of chromatin organization proteins
R-MMU-4615885 SUMOylation of DNA replication proteins
R-MMU-5578749 Transcriptional regulation by small RNAs
R-MMU-5663220 RHO GTPases Activate Formins
R-MMU-68877 Mitotic Prometaphase

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear pore complex protein Nup98-Nup96Imported
Gene namesi
Name:Nup98Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:109404 Nup98

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiA0A140T8J8
PRIDEiA0A140T8J8

Expressioni

Gene expression databases

ExpressionAtlasiA0A140T8J8 baseline and differential

Structurei

3D structure databases

SMRiA0A140T8J8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini738 – 880Peptidase S59InterPro annotationAdd BLAST143

Phylogenomic databases

GeneTreeiENSGT00550000074799
PhylomeDBiA0A140T8J8

Family and domain databases

Gene3Di3.30.1610.10, 1 hit
InterProiView protein in InterPro
IPR037665 Nucleoporin_S59-like
IPR037637 NUP98-NUP96
IPR007230 Peptidase_S59
IPR036903 Peptidase_S59_sf
PANTHERiPTHR23198 PTHR23198, 2 hits
PTHR23198:SF6 PTHR23198:SF6, 2 hits
PfamiView protein in Pfam
PF04096 Nucleoporin2, 1 hit
SUPFAMiSSF82215 SSF82215, 1 hit
PROSITEiView protein in PROSITE
PS51434 NUP_C, 1 hit

Sequencei

Sequence statusi: Complete.

A0A140T8J8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFNKSFGTPF GGSTGGFGTT STFGQNTGFG TTSGGAFGTS AFGSSNNTGG
60 70 80 90 100
LFGNSQTKPG GLFGTSSFSQ PATSTSTGFG FGTSTGTSNS LFGTASTGTS
110 120 130 140 150
LFSSQNNAFA QNKPTGFGNF GTSTSSGGLF GTTNTTSNPF GSTSGSLFGP
160 170 180 190 200
SSFTAAPTGT TIKFNPPTGT DTMVKAGVST NISTKHQCIT AMKEYESKSL
210 220 230 240 250
EELRLEDYQA NRKGPQNQVG GGTTAGLFGS SPATSSATGL FSSSTTNSAF
260 270 280 290 300
SYGQNKTAFG TSTTGFGTNP GGLFGQQNQQ TTSLFSKPFG QATTTPNTGF
310 320 330 340 350
SFGNTSTLGQ PSTNTMGLFG VTQASQPGGL FGTATNTSTG TAFGTGTGLF
360 370 380 390 400
GQPNTGFGAV GSTLFGNNKL TTFGTSTTSA PSFGTTSGGL FGNKPTLTLG
410 420 430 440 450
TNTNTSNFGF GTNNSGSSIF GSKPAAGTLG TGLGTGFGTA LGAGQASLFG
460 470 480 490 500
NNQPKIGGPL GTGAFGAPGF NTSTAILGFG APQAPVALTD PNASAAQQAV
510 520 530 540 550
LQQHLNSLTY SPFGDSPLFR NPMSDPKKKE ERLKPTNPAA QKALTTPTHY
560 570 580 590 600
KLTPRPATRV RPKALQTTGT AKSHLFDGLD DDEPSLANGA FMPKKSIKKL
610 620 630 640 650
VLKNLNNSNL FSPVNHDSED LASPSEYPEN GERFSFLSKP VDENNQQDGE
660 670 680 690 700
DDSLVSRFYT NPIAKPIPQT PESVGNKNNS SSNVEDTIVA LNMRAALRNG
710 720 730 740 750
LEGSSEETSF HDESLQDDRE EIENNAYHIH PAGIVLTKVG YYTIPSMDDL
760 770 780 790 800
AKITNEKGEC IVSDFTIGRK GYGSIYFEGD VNLTNLNLDD IVHIRRKEVI
810 820 830 840 850
VYVDDNQKPP VGEGLNRKAE VTLDGVWPTD KTSRCLIKSP DRLADINYEG
860 870 880 890 900
RLEAVSRKQG AQFKEYRPET GSWVFKVSHF SKYGLQDSDE EEEEHPPKTT
910 920 930 940 950
SKKLKTAPLP PAGQATTFQM TLNGKPAPPP QSQSPEVEQL GRVVELDSDM
960 970 980 990 1000
VDITQEPVPD SVLEESVPED QEPVSASTHI ASSLGINPHV LQIMKASLLV
1010 1020 1030 1040 1050
DEEDVDAMDQ RFGHIPSKGE TVQEICSPRL PISASHSSKS RSIVGGLLQS
1060 1070 1080 1090 1100
KFASGTFLSP SASVQECRTP RTSSRMNIPS TSPWSVPLPL ATVFTVPSPA
1110 1120 1130 1140 1150
PEVQLKTVGI RRQPGLVPLE KSITYGKGKL LMDMALFMGR SFRVGWGPNW
1160 1170 1180
TLANSGEQLH GSHELENHQV ADSMEYGFLP NPVAVKS
Length:1,187
Mass (Da):124,806
Last modified:May 11, 2016 - v1
Checksum:i21C8E66160BC9EFE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC118592 Genomic DNA No translation available.
RefSeqiNP_075355.1, NM_022979.2
UniGeneiMm.439800
Mm.486276

Genome annotation databases

EnsembliENSMUST00000070165; ENSMUSP00000068530; ENSMUSG00000063550
GeneIDi269966

Similar proteinsi

Entry informationi

Entry nameiA0A140T8J8_MOUSE
AccessioniPrimary (citable) accession number: A0A140T8J8
Entry historyiIntegrated into UniProtKB/TrEMBL: May 11, 2016
Last sequence update: May 11, 2016
Last modified: May 23, 2018
This is version 21 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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