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Protein

Ribonuclease R

Gene

rnr

Organism
Escherichia coli (strain B / BL21-DE3)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.UniRule annotation

Catalytic activityi

Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.UniRule annotationSAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionExonucleaseUniRule annotationSAAS annotation, Hydrolase, Nuclease, RNA-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease RUniRule annotation (EC:3.1.13.1UniRule annotation)
Short name:
RNase RUniRule annotation
Gene namesi
Name:rnrUniRule annotation
Ordered Locus Names:ECBD_3855Imported
OrganismiEscherichia coli (strain B / BL21-DE3)Imported
Taxonomic identifieri469008 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000002032 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliA0A140NCR0
SMRiA0A140NCR0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini644 – 725S1 motifInterPro annotationAdd BLAST82

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili45 – 65Sequence analysisAdd BLAST21
Coiled coili403 – 423Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the RNR ribonuclease family. RNase R subfamily.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

KOiK12573
OMAiDWYEYRS

Family and domain databases

HAMAPiMF_01895 RNase_R, 1 hit
InterProiView protein in InterPro
IPR011129 CSD
IPR012340 NA-bd_OB-fold
IPR013223 RNase_B_OB_dom
IPR022966 RNase_II/R_CS
IPR004476 RNase_II/RNase_R
IPR011805 RNase_R
IPR013668 RNase_R_HTH_12
IPR022967 S1_dom
IPR003029 S1_domain
PfamiView protein in Pfam
PF08461 HTH_12, 1 hit
PF08206 OB_RNB, 2 hits
PF00575 S1, 1 hit
SMARTiView protein in SMART
SM00357 CSP, 1 hit
SM00316 S1, 1 hit
SUPFAMiSSF50249 SSF50249, 4 hits
TIGRFAMsiTIGR00358 3_prime_RNase, 1 hit
TIGR02063 RNase_R, 1 hit
PROSITEiView protein in PROSITE
PS01175 RIBONUCLEASE_II, 1 hit
PS50126 S1, 1 hit

Sequencei

Sequence statusi: Complete.

A0A140NCR0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQDPFQERE AEKYANPIPS REFILEHLTK REKPASRDEL AVELHIEGEE
60 70 80 90 100
QLEGLRRRLR AMERDGQLVF TRRQCYALPE RLDLVKGTVI GHRDGYGFLR
110 120 130 140 150
VEGRKDDLYL SSEQMKTCIH GDQVLAQPLG ADRKGRREAR IVRVLVPKTS
160 170 180 190 200
QIVGRYFTEA GVGFVVPDDS RLSFDILIPP DQIMGARMGF VVVVELTQRP
210 220 230 240 250
TRRTKAVGKI VEVLGDNMGT GMAVDIALRT HEIPYIWPQA VEQQVAGLKE
260 270 280 290 300
EVPEEAKAGR VDLRDLPLVT IDGEDARDFD DAVYCEKKRG GGWRLWVAIA
310 320 330 340 350
DVSYYVRPST PLDREARNRG TSVYFPSQVI PMLPEVLSNG LCSLNPQVDR
360 370 380 390 400
LCMVCEMTVS SKGRLTGYKF YEAVMSSHAR LTYTKVWHIL QGDQDLREQY
410 420 430 440 450
APLVKHLEEL HNLYKVLDKA REERGGISFE SEEAKFIFNA ERRIERIEQT
460 470 480 490 500
QRNDAHKLIE ECMILANISA ARFVEKAKEP ALFRIHDKPS TEAITSFRSV
510 520 530 540 550
LAELGLELPG GNKPEPRDYA ELLESVADRP DAEMLQTMLL RSMKQAIYDP
560 570 580 590 600
ENRGHFGLAL QSYAHFTSPI RRYPDLTLHR AIKYLLAKEQ GHQGNTTETG
610 620 630 640 650
GYHYSMEEML QLGQHCSMAE RRADEATRDV ADWLKCDFML DQVGNVFKGV
660 670 680 690 700
ISSVTGFGFF VRLDDLFIDG LVHVSSLDND YYRFDQVGQR LMGESSGQTY
710 720 730 740 750
RLGDRVEVRV EAVNMDERKI DFSLISSERA PRNVGKTARE KAKKGDAGKK
760 770 780 790 800
GGKRRQVGKK VNFEPDSAFR GEKKTKPKAA KKDARKAKKP SAKTQKIAAA
810
TKAKRAAKKK VAE
Length:813
Mass (Da):92,109
Last modified:May 11, 2016 - v1
Checksum:i7516DF0A40D35594
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001665 Genomic DNA Translation: ACT30842.1
RefSeqiWP_000076332.1, NC_012971.2

Genome annotation databases

EnsemblBacteriaiACT30842; ACT30842; ECBD_3855
KEGGiebd:ECBD_3855
ebe:B21_04008
ebl:ECD_04046
PATRICifig|469008.15.peg.4156

Similar proteinsi

Entry informationi

Entry nameiA0A140NCR0_ECOBD
AccessioniPrimary (citable) accession number: A0A140NCR0
Entry historyiIntegrated into UniProtKB/TrEMBL: May 11, 2016
Last sequence update: May 11, 2016
Last modified: February 28, 2018
This is version 14 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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