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Protein

Anti-sigma F factor

Gene

spoIIAB

Organism
Bacillus coagulans
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.UniRule annotation

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseUniRule annotation, Transferase
Biological processSporulationUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Anti-sigma F factorUniRule annotation (EC:2.7.11.1UniRule annotation)
Alternative name(s):
Stage II sporulation protein ABUniRule annotation
Gene namesi
Name:spoIIABUniRule annotation
ORF Names:HMPREF3213_02638Imported
OrganismiBacillus coagulansImported
Taxonomic identifieri1398 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000070376 Componenti: Unassembled WGS sequence

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini35 – 141HATPase_cInterPro annotationAdd BLAST107

Sequence similaritiesi

Belongs to the anti-sigma-factor family.UniRule annotation

Family and domain databases

CDDicd00075. HATPase_c. 1 hit.
Gene3Di3.30.565.10. 1 hit.
HAMAPiMF_00637. Anti_sigma_F. 1 hit.
InterProiView protein in InterPro
IPR010194. Anti-sigma_F.
IPR003594. HATPase_C.
IPR036890. HATPase_C_sf.
PANTHERiPTHR35526:SF2. PTHR35526:SF2. 1 hit.
PfamiView protein in Pfam
PF13581. HATPase_c_2. 1 hit.
SMARTiView protein in SMART
SM00387. HATPase_c. 1 hit.
SUPFAMiSSF55874. SSF55874. 1 hit.
TIGRFAMsiTIGR01925. spIIAB. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A133KJA1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKNKMQLQFS ALSRNESFAR VAVAAFVAQL DPTLDELTEI KTVVSEAVTN
60 70 80 90 100
AIIHGYEENP DGMVYVSAAI CDDGTVEITV RDEGKGIADI EEARQPLFTT
110 120 130 140
KPDLERSGMG FTIMENFMDD VEIKSQPESG TIIRLKKHLA LKNALCN
Length:147
Mass (Da):16,208
Last modified:June 8, 2016 - v1
Checksum:i5394ABDC87FD0DC8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LRPN01000116 Genomic DNA. Translation: KWZ79534.1.
RefSeqiWP_061087018.1. NZ_KQ955881.1.

Genome annotation databases

EnsemblBacteriaiKWZ79534; KWZ79534; HMPREF3213_02638.
PATRICifig|1398.22.peg.2642.

Similar proteinsi

Entry informationi

Entry nameiA0A133KJA1_BACCO
AccessioniPrimary (citable) accession number: A0A133KJA1
Entry historyiIntegrated into UniProtKB/TrEMBL: June 8, 2016
Last sequence update: June 8, 2016
Last modified: October 25, 2017
This is version 9 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteomeImported