Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Phospho-N-acetylmuramoyl-pentapeptide-transferase

Gene

mraY

Organism
Legionella pneumophila
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan.UniRule annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

UDP-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala) + undecaprenyl phosphate = UMP + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol.UniRule annotation

Pathwayi: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferaseUniRule annotationImported
Biological processCell cycle, Cell divisionUniRule annotation, Cell shape, Cell wall biogenesis/degradationUniRule annotation, Peptidoglycan synthesisUniRule annotation

Enzyme and pathway databases

UniPathwayiUPA00219

Names & Taxonomyi

Protein namesi
Recommended name:
Phospho-N-acetylmuramoyl-pentapeptide-transferaseUniRule annotation (EC:2.7.8.13UniRule annotation)
Alternative name(s):
UDP-MurNAc-pentapeptide phosphotransferaseUniRule annotation
Gene namesi
Name:mraYUniRule annotation
ORF Names:PtVF89_03890Imported
OrganismiLegionella pneumophilaImported
Taxonomic identifieri446 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesLegionellaceaeLegionella
Proteomesi
  • UP000070201 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei27 – 48HelicalUniRule annotationAdd BLAST22
Transmembranei69 – 91HelicalUniRule annotationAdd BLAST23
Transmembranei97 – 114HelicalUniRule annotationAdd BLAST18
Transmembranei134 – 152HelicalUniRule annotationAdd BLAST19
Transmembranei172 – 193HelicalUniRule annotationAdd BLAST22
Transmembranei200 – 219HelicalUniRule annotationAdd BLAST20
Transmembranei239 – 256HelicalUniRule annotationAdd BLAST18
Transmembranei263 – 284HelicalUniRule annotationAdd BLAST22
Transmembranei290 – 311HelicalUniRule annotationAdd BLAST22
Transmembranei339 – 358HelicalUniRule annotationAdd BLAST20

GO - Cellular componenti

Keywords - Cellular componenti

Cell membraneUniRule annotation, Membrane

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 4 family. MraY subfamily.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Family and domain databases

CDDicd06852 GT_MraY, 1 hit
HAMAPiMF_00038 MraY, 1 hit
InterProiView protein in InterPro
IPR000715 Glycosyl_transferase_4
IPR003524 PNAcMuramoyl-5peptid_Trfase
IPR018480 PNAcMuramoyl-5peptid_Trfase_CS
PANTHERiPTHR22926 PTHR22926, 1 hit
PfamiView protein in Pfam
PF00953 Glycos_transf_4, 1 hit
PF10555 MraY_sig1, 1 hit
TIGRFAMsiTIGR00445 mraY, 1 hit
PROSITEiView protein in PROSITE
PS01347 MRAY_1, 1 hit
PS01348 MRAY_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A128Q8D1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLYWLTQLLQ GQYHAFRVFQ YLTFRSILAS LTALIVGLLC GPLMIRWLRG
60 70 80 90 100
LQIGQMVRND GPQTHLSKAG TPTMGGVLIL LAITVSCLLW CDLRQTSLWL
110 120 130 140 150
VLLVTLANGL VGWVDDYRKL VLKNSKGLPG RWKYFWQSII ALVAVSYLYW
160 170 180 190 200
NASLPVHTQL TVPFFKTVTW DLGIFFPVLA YFVIVGSSNA VNLTDGLDGL
210 220 230 240 250
AIMPIVMVAG ALGVFAYASS NAVYSNYLGI PYVPNTGELT IFCSSIVGAG
260 270 280 290 300
LGFLWYNSYP AQVFMGDVGS LALGAALGIV AVVVRQELVL LIMGGLFVIE
310 320 330 340 350
TLSVILQVGY FKYSGGKRLF RMAPLHHHFE LKGWSEPKVI VRFWIITVVF
360
VLCGLATLKL R
Length:361
Mass (Da):39,910
Last modified:May 11, 2016 - v1
Checksum:i2179E4DDF0D412FD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LCUQ01000009 Genomic DNA Translation: KXB28195.1
RefSeqiWP_027229100.1, NZ_PQWY01000019.1

Genome annotation databases

EnsemblBacteriaiKXB28195; KXB28195; PtVF89_03890
PATRICifig|446.142.peg.3251

Similar proteinsi

Entry informationi

Entry nameiA0A128Q8D1_LEGPN
AccessioniPrimary (citable) accession number: A0A128Q8D1
Entry historyiIntegrated into UniProtKB/TrEMBL: May 11, 2016
Last sequence update: May 11, 2016
Last modified: May 23, 2018
This is version 11 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health