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Protein

Olfactory receptor

Gene

OR2B6

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer
Biological processOlfactionUniRule annotationSAAS annotation, Sensory transduction

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory receptorUniRule annotation
Gene namesi
Name:OR2B6Imported
ORF Names:hCG_1999027Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei25 – 48HelicalUniRule annotationAdd BLAST24
Transmembranei60 – 81HelicalUniRule annotationAdd BLAST22
Transmembranei101 – 120HelicalUniRule annotationAdd BLAST20
Transmembranei140 – 158HelicalUniRule annotationAdd BLAST19
Transmembranei205 – 226HelicalUniRule annotationAdd BLAST22
Transmembranei238 – 261HelicalUniRule annotationAdd BLAST24
Transmembranei273 – 292HelicalUniRule annotationAdd BLAST20

Keywords - Cellular componenti

Cell membraneUniRule annotationSAAS annotation, Membrane

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini41 – 290G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST250

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

KOiK04257.
OMAiVWLSTLT.

Family and domain databases

InterProiView protein in InterPro
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
PfamiView protein in Pfam
PF13853. 7tm_4. 1 hit.
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiView protein in PROSITE
PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A126GW55-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNWVNDSIIQ EFILLGFSDR PWLEFPLLVV FLISYTVTIF GNLTIILVSR
60 70 80 90 100
LDTKLHTPMY FFLTNLSLLD LCYTTCTVPQ MLVNLCSIRK VISYRGCVAQ
110 120 130 140 150
LFIFLALGAT EYLLLAVMSF DRFVAICRPL HYSVIMHQRL CLQLAAASWV
160 170 180 190 200
TGFSNSVWLS TLTLQLPLCD PYVIDHFLCE VPALLKLSCV ETTANEAELF
210 220 230 240 250
LVSELFHLIP LTLILISYAF IVRAVLRIQS AEGRQKAFGT CGSHLIVVSL
260 270 280 290 300
FYSTAVSVYL QPPSPSSKDQ GKMVSLFYGI IAPMLNPLIY TLRNKEVKEG
310
FKRLVARVFL IKK
Length:313
Mass (Da):35,414
Last modified:May 11, 2016 - v1
Checksum:i71D459541ACF5301
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KP290463 Genomic DNA. Translation: ALI87627.1.
CH471081 Genomic DNA. Translation: EAX03127.1.
RefSeqiNP_036499.1. NM_012367.1.
UniGeneiHs.532145.

Genome annotation databases

GeneIDi26212.
KEGGihsa:26212.

Similar proteinsi

Entry informationi

Entry nameiA0A126GW55_HUMAN
AccessioniPrimary (citable) accession number: A0A126GW55
Entry historyiIntegrated into UniProtKB/TrEMBL: May 11, 2016
Last sequence update: May 11, 2016
Last modified: November 22, 2017
This is version 17 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.