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Protein

Guanylate kinase

Gene

gmk

Organism
Lactobacillus casei (strain BD-II)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotationSAAS annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotationSAAS annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi12 – 19ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinaseUniRule annotationSAAS annotationImported, Transferase
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotationSAAS annotation (EC:2.7.4.8UniRule annotationSAAS annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmkUniRule annotation
Ordered Locus Names:LCBD_1830Imported
OrganismiLactobacillus casei (strain BD-II)Imported
Taxonomic identifieri998820 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
Proteomesi
  • UP000006850 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 184Guanylate kinase-likeInterPro annotationAdd BLAST180

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotationSAAS annotation

Phylogenomic databases

KOiK00942.
OMAiYGTLKSE.

Family and domain databases

HAMAPiMF_00328. Guanylate_kinase. 1 hit.
InterProiView protein in InterPro
IPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like_dom.
IPR017665. Guanylate_kinase.
IPR020590. Guanylate_kinase_CS.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00625. Guanylate_kin. 1 hit.
SMARTiView protein in SMART
SM00072. GuKc. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR03263. guanyl_kin. 1 hit.
PROSITEiView protein in PROSITE
PS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A125U869-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHERGMLIVL SGPSGVGKGT VRQAMLDGNY RDFQYSISMT TRQMRPGEVD
60 70 80 90 100
GVDYYFRTKA QFEHEIATGG MLEYAKYVEN YYGTPLKYVN ETLDAGRDVL
110 120 130 140 150
LEIEVNGAMQ VRKKCPNGVF IFLTPPDLSE LRHRLKGRGT DDDVTIDKRI
160 170 180 190 200
RKAASEITMM ENYDYAVVND KVDLAVKRIE RIIESEHLRV PRVIDRYKGM

LASADLAR
Length:208
Mass (Da):23,734
Last modified:April 13, 2016 - v1
Checksum:i44F9B701D8B3C864
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002618 Genomic DNA. Translation: AEA57326.1.
RefSeqiWP_003564691.1. NC_017474.1.

Genome annotation databases

EnsemblBacteriaiAEA57326; AEA57326; LCBD_1830.
GeneIDi31582265.
KEGGilcs:LCBD_1830.
PATRICifig|998820.3.peg.1813.

Similar proteinsi

Entry informationi

Entry nameiA0A125U869_LACCD
AccessioniPrimary (citable) accession number: A0A125U869
Entry historyiIntegrated into UniProtKB/TrEMBL: April 13, 2016
Last sequence update: April 13, 2016
Last modified: September 27, 2017
This is version 11 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported