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Protein

Phosphoenolpyruvate carboxylase

Gene

ppcA

Organism
Thermococcus sibiricus
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotation
Biological processCarbon dioxide fixationUniRule annotation
LigandMagnesiumUniRule annotation, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcAUniRule annotation
ORF Names:XD54_1889Imported
OrganismiThermococcus sibiricusImported
Taxonomic identifieri172049 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaeThermococcus
Proteomesi
  • UP000053911 Componenti: Unassembled WGS sequence

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 2 family.UniRule annotation

Family and domain databases

HAMAPiMF_01904. PEPcase_type2. 1 hit.
InterProiView protein in InterPro
IPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
PfamiView protein in Pfam
PF14010. PEPcase_2. 1 hit.
PIRSFiPIRSF006677. UCP006677. 1 hit.
SUPFAMiSSF51621. SSF51621. 1 hit.
TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A101EK28-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIPRTMSTQH PDNVYIPFFA HESSLGGEDE VLEAFYAFSV LGVQEQMWDF
60 70 80 90 100
EGKEVDEFVI KKLLEKYGQF FKKKKLGRDI RITPRVPNPS VEKAEAKLLL
110 120 130 140 150
ETLESIPRSA DYAKLFYGEE IAPIFEVILP MTTSSKEIER VYELYKRYII
160 170 180 190 200
GKQYKRVYDI KIYEWIGEFY PEEINVIPLF ETKEAILNSH EILKEYLTGK
210 220 230 240 250
NFEYQRVFLA RSDPAMNYGL ISAVIYDKYA LFNIQELEEE LSVPIYPIIG
260 270 280 290 300
VGSAPFRGHF IPENVENTIK EYPNVQTFTV QSSFKYDNDP KEVIRAIEKV
310 320 330 340 350
NERKRKKSAS VDEGVFKILE KYEKEYTAEL KLLAPYIREI AKFVPSRRKR
360 370 380 390 400
KLHIGLFGYS RKINGEVLPR AIKFTASLYS LGVPPELLGL STLSEKDIEE
410 420 430 440 450
LAEYYYGLYR DLEFALKFFN PKTSQKFKFL NKIVKLQKEM GIEAEERHQT
460 470
LTSQIISGKF EESVIVQAAD IRGFLG
Length:476
Mass (Da):55,355
Last modified:April 13, 2016 - v1
Checksum:i849B167A7DA54C5A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LGFD01000059 Genomic DNA. Translation: KUK16820.1.

Genome annotation databases

GeneIDi8095863.
PATRICifig|172049.5.peg.2147.

Similar proteinsi

Entry informationi

Entry nameiA0A101EK28_9EURY
AccessioniPrimary (citable) accession number: A0A101EK28
Entry historyiIntegrated into UniProtKB/TrEMBL: April 13, 2016
Last sequence update: April 13, 2016
Last modified: September 27, 2017
This is version 7 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteomeImported