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Protein

Glucose-6-phosphate isomerase

Gene

pgiA

Organism
Thermococcales archaeon 44_46
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgiA)
  3. no protein annotated in this organism
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi89IronUniRule annotation1
Metal bindingi91IronUniRule annotation1
Metal bindingi98IronUniRule annotation1
Metal bindingi137IronUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationImported
Biological processGluconeogenesisUniRule annotation, GlycolysisUniRule annotation
LigandIronUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiAUniRule annotation
ORF Names:XD43_0327Imported
OrganismiThermococcales archaeon 44_46Imported
Taxonomic identifieri1635283 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcales
Proteomesi
  • UP000054069 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 184GPIInterPro annotationAdd BLAST160

Sequence similaritiesi

Belongs to the archaeal-type GPI family.UniRule annotation

Family and domain databases

Gene3Di2.60.120.10, 1 hit
HAMAPiMF_01410 G6P_isomerase_arch, 1 hit
InterProiView protein in InterPro
IPR016758 G6P_isomerase_archaea/bacteria
IPR010551 G6P_isomerase_prok
IPR014710 RmlC-like_jellyroll
IPR011051 RmlC_Cupin_sf
PfamiView protein in Pfam
PF06560 GPI, 1 hit
PIRSFiPIRSF019325 Glucose-6-phosphate_isomerase, 1 hit
SUPFAMiSSF51182 SSF51182, 1 hit

Sequencei

Sequence statusi: Complete.

A0A101DN50-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKYKEPFGVK LDFETGAIEN AKKSVRRLSD LKGYFVDEEA WKKMVEEGDP
60 70 80 90 100
VVYEVYAIEQ EEKEGDLNFA TTVLYPGKVG NEFFMTKGHY HAKIDRAEVY
110 120 130 140 150
FALKGKGGML LQTPEGEARF IEMEPGTIVY VPPYWAHRTV NTGDEPFIFL
160 170 180 190
ALYPADAGHD YGTIAEKGFS KIVVEENGKV VVKDNPKWKE
Length:190
Mass (Da):21,587
Last modified:April 13, 2016 - v1
Checksum:i4A69A0D63929C593
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LGET01000017 Genomic DNA Translation: KUK00015.1

Genome annotation databases

PATRICifig|1635283.4.peg.668

Similar proteinsi

Entry informationi

Entry nameiA0A101DN50_9EURY
AccessioniPrimary (citable) accession number: A0A101DN50
Entry historyiIntegrated into UniProtKB/TrEMBL: April 13, 2016
Last sequence update: April 13, 2016
Last modified: March 28, 2018
This is version 13 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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