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Protein

Glutamate--tRNA ligase

Gene

gltX

Organism
Campylobacter jejuni BJ-CJGB96114
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).UniRule annotation

Catalytic activityi

ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei238ATPUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetaseUniRule annotationImported, Ligase
Biological processProtein biosynthesisUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate--tRNA ligaseUniRule annotation (EC:6.1.1.17UniRule annotation)
Alternative name(s):
Glutamyl-tRNA synthetaseUniRule annotation
Short name:
GluRSUniRule annotation
Gene namesi
Name:gltXUniRule annotation
ORF Names:K679_1504Imported
OrganismiCampylobacter jejuni BJ-CJGB96114Imported
Taxonomic identifieri1316920 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliA0A0W8LBQ3.
SMRiA0A0W8LBQ3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 300tRNA-synt_1cInterPro annotationAdd BLAST298

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi6 – 16"HIGH" regionUniRule annotationAdd BLAST11
Motifi235 – 239"KMSKS" regionUniRule annotation5

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.UniRule annotation

Family and domain databases

Gene3Di1.10.10.350. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00022. Glu_tRNA_synth_type1. 1 hit.
InterProiView protein in InterPro
IPR008925. aa-tRNA-synth_I_codon-bd.
IPR020751. aa-tRNA-synth_I_codon-bd_sub2.
IPR001412. aa-tRNA-synth_I_CS.
IPR004527. Glu-tRNA-ligase_bac/mito.
IPR000924. Glu/Gln-tRNA-synth.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR014729. Rossmann-like_a/b/a_fold.
PfamiView protein in Pfam
PF00749. tRNA-synt_1c. 1 hit.
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF48163. SSF48163. 1 hit.
TIGRFAMsiTIGR00464. gltX_bact. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A0W8LBQ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYRFAPSPTG DMHIGNLRAA IFNYICARQK NMDFILRIED TDKARNIAGK
60 70 80 90 100
EEEIKEILNL FGISWQHYYI QSENLKFHRQ MALKLVSEKK AFACFCTEEE
110 120 130 140 150
LEAKKELAKK QGKAYRYDGT CEKLADIDVL ECEKPFVIRL KKPTHTMKFT
160 170 180 190 200
DFIKGELSFE PENIDSFVIM RTDKTPTYNF ACAVDDMLEN VTCIIRGEDH
210 220 230 240 250
VSNTPKQEHI RASLGYNKAM TYAHLPIILN EEGVKMSKRE AHSSVKWLLE
260 270 280 290 300
SGILPSAIAN YLIMLGNKTP CEIFTLEEAI KWFDISKVSK APARFDLKKL
310 320 330 340 350
LQINREHIKM IKDDELNKIL DLNKDLAQLA KFYTQEASTI KELKEKMRAI
360 370 380 390 400
FNTKDFGEFE TECKILKELL KDIELFENYE DFKNELLSKS DLKGKKFFMP
410 420 430
LRIILTGNIH GPELSDLYPY IKNFIHELAR I
Length:431
Mass (Da):50,103
Last modified:March 16, 2016 - v1
Checksum:iE5FDDDDE8FC24A2E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KQ950116 Genomic DNA. Translation: KUY39975.1.
RefSeqiWP_002856800.1. NZ_KQ950116.1.

Genome annotation databases

PATRICifig|1316920.3.peg.1506.

Similar proteinsi

Entry informationi

Entry nameiA0A0W8LBQ3_CAMJU
AccessioniPrimary (citable) accession number: A0A0W8LBQ3
Entry historyiIntegrated into UniProtKB/TrEMBL: March 16, 2016
Last sequence update: March 16, 2016
Last modified: March 28, 2018
This is version 17 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation