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Protein
Submitted name:

Polypyrimidine tract-binding protein 1

Gene

PTBP1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRNA-bindingPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Polypyrimidine tract-binding protein 1Imported
Gene namesi
Name:PTBP1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

HGNCiHGNC:9583 PTBP1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000011304

PTM / Processingi

Proteomic databases

PeptideAtlasiA0A0U1RRM4

Expressioni

Gene expression databases

ExpressionAtlasiA0A0U1RRM4 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini59 – 143RRMInterPro annotationAdd BLAST85
Domaini215 – 291RRMInterPro annotationAdd BLAST77
Domaini394 – 468RRMInterPro annotationAdd BLAST75
Domaini511 – 586RRMInterPro annotationAdd BLAST76

Phylogenomic databases

GeneTreeiENSGT00550000074508
OMAiSEECAQT

Family and domain databases

CDDicd12777 RRM1_PTBP1, 1 hit
cd12693 RRM2_PTBP1_like, 1 hit
cd12695 RRM3_PTBP1, 1 hit
Gene3Di3.30.70.330, 4 hits
InterProiView protein in InterPro
IPR006536 HnRNP-L/PTB
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR034798 PTBP1/2/3_RRM2
IPR035000 PTBP1_RRM1
IPR035001 PTBP1_RRM3
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
PfamiView protein in Pfam
PF00076 RRM_1, 2 hits
SMARTiView protein in SMART
SM00360 RRM, 4 hits
SUPFAMiSSF54928 SSF54928, 4 hits
TIGRFAMsiTIGR01649 hnRNP-L_PTB, 1 hit
PROSITEiView protein in PROSITE
PS50102 RRM, 4 hits

Sequencei

Sequence statusi: Complete.

A0A0U1RRM4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDGIVPDIAV GTKRGSDELF STCVTNGPFI MSSNSASAAN GNDSKKFKGD
60 70 80 90 100
SRSAGVPSRV IHIRKLPIDV TEGEVISLGL PFGKVTNLLM LKGKNQAFIE
110 120 130 140 150
MNTEEAANTM VNYYTSVTPV LRGQPIYIQF SNHKELKTDS SPNQAVRGPA
160 170 180 190 200
ADPSSPGTSG VGPAAGAGDS RLCLPQRAQA ALQAVNSVQS GNLALAASAA
210 220 230 240 250
AVDAGMAMAG QSPVLRIIVE NLFYPVTLDV LHQIFSKFGT VLKIITFTKN
260 270 280 290 300
NQFQALLQYA DPVSAQHAKL SLDGQNIYNA CCTLRIDFSK LTSLNVKYNN
310 320 330 340 350
DKSRDYTRPD LPSGDSQPSL DQTMAAAFGA PGIISASPYA GAGFPPTFAI
360 370 380 390 400
PQAAGLSVPN VHGALAPLAI PSAAAAAAAA GRIAIPGLAG AGNSVLLVSN
410 420 430 440 450
LNPERVTPQS LFILFGVYGD VQRVKILFNK KENALVQMAD GNQAQLAMSH
460 470 480 490 500
LNGHKLHGKP IRITLSKHQN VQLPREGQED QGLTKDYGNS PLHRFKKPGS
510 520 530 540 550
KNFQNIFPPS ATLHLSNIPP SVSEEDLKVL FSSNGGVVKG FKFFQKDRKM
560 570 580
ALIQMGSVEE AVQALIDLHN HDLGENHHLR VSFSKSTI
Length:588
Mass (Da):62,464
Last modified:February 17, 2016 - v1
Checksum:i448018329EE6F329
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006273 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000635647; ENSP00000489604; ENSG00000011304

Similar proteinsi

Entry informationi

Entry nameiA0A0U1RRM4_HUMAN
AccessioniPrimary (citable) accession number: A0A0U1RRM4
Entry historyiIntegrated into UniProtKB/TrEMBL: February 17, 2016
Last sequence update: February 17, 2016
Last modified: April 25, 2018
This is version 21 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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