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Protein

DEAD-box ATP-dependent RNA helicase CshA

Gene

cshA_3

Organism
Streptococcus pneumoniae
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity.UniRule annotation

Catalytic activityi

ATP + H2O = ADP + phosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHelicaseUniRule annotationImported, Hydrolase, RNA-bindingUniRule annotation
Biological processStress responseUniRule annotation
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DEAD-box ATP-dependent RNA helicase CshAUniRule annotation (EC:3.6.4.13UniRule annotation)
Gene namesi
Name:cshA_3Imported
Synonyms:cshAUniRule annotation
ORF Names:ERS021733_04923Imported
OrganismiStreptococcus pneumoniaeImported
Taxonomic identifieri1313 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000041439 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Oligomerizes, may be a member of the RNA degradosome.UniRule annotation

Structurei

3D structure databases

SMRiA0A0T8Q2H4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 31Q_MOTIFInterPro annotationAdd BLAST29
Domaini34 – 204Helicase ATP-bindingInterPro annotationAdd BLAST171
Domaini215 – 375Helicase C-terminalInterPro annotationAdd BLAST161

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi3 – 31Q motifPROSITE-ProRule annotationAdd BLAST29

Sequence similaritiesi

Belongs to the DEAD box helicase family. CshA subfamily.UniRule annotation

Family and domain databases

HAMAPiMF_01493. DEAD_helicase_CshA. 1 hit.
InterProiView protein in InterPro
IPR011545. DEAD/DEAH_box_helicase_dom.
IPR030880. DEAD_helicase_CshA.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR000629. RNA-helicase_DEAD-box_CS.
IPR014014. RNA_helicase_DEAD_Q_motif.
PfamiView protein in Pfam
PF00270. DEAD. 1 hit.
PF00271. Helicase_C. 1 hit.
SMARTiView protein in SMART
SM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiView protein in PROSITE
PS00039. DEAD_ATP_HELICASE. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS51195. Q_MOTIF. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A0T8Q2H4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTITFQDFNL SSDLMKAINR MGFEEATPIQ AQTIPLGLSN KDVIGQAQTG
60 70 80 90 100
TGKTAAFGIP LVEKINPESP NIQAIVIAPT RELAIQVSEE LYKIGQDKRA
110 120 130 140 150
KVLPIYGGQD IGRQIRALKK NPNIIVGTPG RLLDHINRRT IRLNNVNTVV
160 170 180 190 200
MDEADEMLNM GFIDDIESIL SNVPSEHQTL LFSATMPAPI KRIAERFMTE
210 220 230 240 250
PEHVKVKAKE MTVSNIQQFY LEVQERKKFD TLTRLLDIQS PELAIVFGRT
260 270 280 290 300
KRRVDELAEA LNLRGYAAEG IHGDLTQAKR MVALRKFKEG AIEVLVATDV
310 320 330 340 350
AARGLDISGV THVYNFDVPQ DPESYVHRIG RTGRAGKTGM AMTFITPREK
360 370 380 390 400
SMLRAIEQTT KRKMDRMKEP TLDEALEGQQ QVTVERLRTT ISENNLNFYM
410 420 430 440 450
TAAAELLEDH DAVTVVAAAI KMATKEPDDT PVRLTDEAPM VSKRYKNQRS
460 470 480 490
SKRRDGQGGG YRGGKGKSNN RSSYDKKRSN DRRSSGDRRQ KKSY
Length:494
Mass (Da):55,330
Last modified:February 17, 2016 - v1
Checksum:iA44C5EAE314E46ED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CLUP01000114 Genomic DNA. Translation: CJS86360.1.

Genome annotation databases

EnsemblBacteriaiCJS86360; CJS86360; ERS021733_04923.

Similar proteinsi

Entry informationi

Entry nameiA0A0T8Q2H4_STREE
AccessioniPrimary (citable) accession number: A0A0T8Q2H4
Entry historyiIntegrated into UniProtKB/TrEMBL: February 17, 2016
Last sequence update: February 17, 2016
Last modified: May 10, 2017
This is version 10 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported