Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Phospho-N-acetylmuramoyl-pentapeptide-transferase

Gene

mraY

Organism
Rickettsia rhipicephali
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan.UniRule annotation

Catalytic activityi

UDP-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala) + undecaprenyl phosphate = UMP + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol.UniRule annotation

Pathwayi: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferaseUniRule annotationImported
Biological processCell cycle, Cell divisionUniRule annotation, Cell shape, Cell wall biogenesis/degradationUniRule annotation, Peptidoglycan synthesisUniRule annotation

Enzyme and pathway databases

UniPathwayiUPA00219.

Names & Taxonomyi

Protein namesi
Recommended name:
Phospho-N-acetylmuramoyl-pentapeptide-transferaseUniRule annotation (EC:2.7.8.13UniRule annotation)
Alternative name(s):
UDP-MurNAc-pentapeptide phosphotransferaseUniRule annotation
Gene namesi
Name:mraYUniRule annotationImported
ORF Names:ASQ44_02665Imported
OrganismiRickettsia rhipicephaliImported
Taxonomic identifieri33992 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
Proteomesi
  • UP000061212 Componenti: Chromosome

Subcellular locationi

  • Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei28 – 49HelicalUniRule annotationAdd BLAST22
Transmembranei70 – 92HelicalUniRule annotationAdd BLAST23
Transmembranei98 – 115HelicalUniRule annotationAdd BLAST18
Transmembranei135 – 152HelicalUniRule annotationAdd BLAST18
Transmembranei172 – 193HelicalUniRule annotationAdd BLAST22
Transmembranei200 – 219HelicalUniRule annotationAdd BLAST20
Transmembranei239 – 256HelicalUniRule annotationAdd BLAST18
Transmembranei263 – 283HelicalUniRule annotationAdd BLAST21
Transmembranei289 – 311HelicalUniRule annotationAdd BLAST23
Transmembranei339 – 358HelicalUniRule annotationAdd BLAST20

GO - Cellular componenti

Keywords - Cellular componenti

Cell membraneUniRule annotation, Membrane

Structurei

3D structure databases

SMRiA0A0S2C8W7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 4 family. MraY subfamily.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Family and domain databases

CDDicd06852. GT_MraY. 1 hit.
HAMAPiMF_00038. MraY. 1 hit.
InterProiView protein in InterPro
IPR000715. Glycosyl_transferase_4.
IPR003524. PNAcMuramoyl-5peptid_Trfase.
IPR018480. PNAcMuramoyl-5peptid_Trfase_CS.
PANTHERiPTHR22926. PTHR22926. 1 hit.
PfamiView protein in Pfam
PF00953. Glycos_transf_4. 1 hit.
TIGRFAMsiTIGR00445. mraY. 1 hit.
PROSITEiView protein in PROSITE
PS01347. MRAY_1. 1 hit.
PS01348. MRAY_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A0S2C8W7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLYNLLLPHI HNSHIANLFH YITFRSGLAI IITLSLSFIT GPILIKFLRS
60 70 80 90 100
LQKNGQPIRS DGPESHQTKV GTPTMGGIMI ILSSCLSTLL LADLTNKYTW
110 120 130 140 150
ITLFGFISFG IIGFMDDYAK VTKNNHYGVR GKSKLLLQGI ISFIICVLLE
160 170 180 190 200
YLDKSPSHLL NVPFFKNLSL DLGYFYIVFA IFVIVGSSNA VNLTDGLDGL
210 220 230 240 250
ATVPIAFTAG SFALISYLVG NLIYSNYLQL TYIPNTGELT VLCAGLVGSC
260 270 280 290 300
LGFLWFNAQP AEVFMGDTGS LSLGGVLGII SVITKHEIVL AIVGGLFVIE
310 320 330 340 350
TASVILQVYY FKATKGKRIF KMAPLHHHFE KHGWAESKVV IRFWIISVIF
360
ALIGLSSLKL R
Length:361
Mass (Da):39,703
Last modified:February 17, 2016 - v1
Checksum:i27E70137E7260BE7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP013133 Genomic DNA. Translation: ALN41099.1.
RefSeqiWP_014365610.1. NZ_CP013133.1.

Genome annotation databases

EnsemblBacteriaiALN41099; ALN41099; ASQ44_02665.

Similar proteinsi

Entry informationi

Entry nameiA0A0S2C8W7_RICRH
AccessioniPrimary (citable) accession number: A0A0S2C8W7
Entry historyiIntegrated into UniProtKB/TrEMBL: February 17, 2016
Last sequence update: February 17, 2016
Last modified: September 27, 2017
This is version 11 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported