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Protein
Submitted name:

Retinoblastoma-binding protein 4,-like

Gene

rbb4l

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

ReactomeiR-DRE-212300. PRC2 methylates histones and DNA.
R-DRE-2559580. Oxidative Stress Induced Senescence.
R-DRE-3214841. PKMTs methylate histone lysines.
R-DRE-3214847. HATs acetylate histones.
R-DRE-3214858. RMTs methylate histone arginines.
R-DRE-6804758. Regulation of TP53 Activity through Acetylation.
R-DRE-73762. RNA Polymerase I Transcription Initiation.
R-DRE-8943724. Regulation of PTEN gene transcription.
R-DRE-8951664. Neddylation.
R-DRE-8953750. Transcriptional Regulation by E2F6.

Names & Taxonomyi

Protein namesi
Submitted name:
Retinoblastoma-binding protein 4,-likeImported
Gene namesi
Name:rbb4lImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 11

Organism-specific databases

ZFINiZDB-GENE-030131-848. rbb4l.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

Expressioni

Gene expression databases

ExpressionAtlasiA0A0R4I9A9. baseline.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini173 – 412WD_REPEATS_REGIONInterPro annotationAdd BLAST240
Repeati173 – 208WDPROSITE-ProRule annotationAdd BLAST36
Repeati223 – 265WDPROSITE-ProRule annotationAdd BLAST43
Repeati269 – 305WDPROSITE-ProRule annotationAdd BLAST37
Repeati313 – 355WDPROSITE-ProRule annotationAdd BLAST43
Repeati370 – 404WDPROSITE-ProRule annotationAdd BLAST35

Keywords - Domaini

RepeatSAAS annotation, WD repeatPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00570000079069.
OMAiVAWHVLH.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiView protein in InterPro
IPR020472. G-protein_beta_WD-40_rep.
IPR022052. Histone-bd_RBBP4_N.
IPR015943. WD40/YVTN_repeat-like_dom_sf.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
IPR036322. WD40_repeat_dom_sf.
PfamiView protein in Pfam
PF12265. CAF1C_H4-bd. 1 hit.
PF00400. WD40. 5 hits.
PRINTSiPR00320. GPROTEINBRPT.
SMARTiView protein in SMART
SM00320. WD40. 6 hits.
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiView protein in PROSITE
PS00678. WD_REPEATS_1. 3 hits.
PS50082. WD_REPEATS_2. 5 hits.
PS50294. WD_REPEATS_REGION. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A0R4I9A9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADKEVYDDA VEERVINEEY KIWKKNTPFL YDLVMTHALE WPSLTVQWLP
60 70 80 90 100
DVNRPEGKDY VVHRLVLGTH TSDEQNHLVI ASVQIPNDDA QFDASHYDSE
110 120 130 140 150
KGAEFGGFGS VSGKIEIEIK INHEGEVNRA RYMPQNPCII ATKTPTSDVL
160 170 180 190 200
VFDYTKHPSK PDPSGDCSPD LRLRGHQKEG YGLSWNPNLS GNLLSASDDH
210 220 230 240 250
TICLWDISGA PKEGKIVDAK TIFTGHTAVV EDVSWHLLHE SLFGSVADDQ
260 270 280 290 300
KLMIWDTRSN NTSKPSHSVD AHTAEVNCLS FNPYSEFILA TGSADKTVAL
310 320 330 340 350
WDLRNLKLKL HSFESHKDEI FQVQWSPHNE TILASSGTDR RLNVWDLSKI
360 370 380 390 400
GEEQSAEDAE DGPPELLFIH GGHTAKISDF SWNPNEPWVI CSVSEDNIMQ
410 420 430 440
VWQMAENIYN DEEPDTPASE LGTGVITDLI LNIQPLLTLH ILLFSIIP
Length:448
Mass (Da):50,246
Last modified:January 20, 2016 - v1
Checksum:iF3778F46B0ED7655
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX004876 Genomic DNA. No translation available.
CR450764 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSDART00000008144; ENSDARP00000025096; ENSDARG00000015208.

Similar proteinsi

Entry informationi

Entry nameiA0A0R4I9A9_DANRE
AccessioniPrimary (citable) accession number: A0A0R4I9A9
Entry historyiIntegrated into UniProtKB/TrEMBL: January 20, 2016
Last sequence update: January 20, 2016
Last modified: November 22, 2017
This is version 18 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported