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Protein

Holliday junction ATP-dependent DNA helicase RuvA

Gene

ruvA

Organism
Bradyrhizobium valentinum
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.UniRule annotationSAAS annotation

Catalytic activityi

ATP + H2O = ADP + phosphate.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation, HelicaseUniRule annotationSAAS annotationImported, Hydrolase
Biological processDNA damage, DNA recombinationUniRule annotationSAAS annotation, DNA repairUniRule annotationSAAS annotation, SOS responseUniRule annotationSAAS annotation
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Holliday junction ATP-dependent DNA helicase RuvAUniRule annotationSAAS annotation (EC:3.6.4.12UniRule annotationSAAS annotation)
Gene namesi
Name:ruvAUniRule annotation
ORF Names:CP49_11560Imported
OrganismiBradyrhizobium valentinumImported
Taxonomic identifieri1518501 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium
Proteomesi
  • UP000051913 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Interactioni

Subunit structurei

Forms a complex with RuvB.UniRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini73 – 92HhH1InterPro annotationAdd BLAST20
Domaini108 – 127HhH1InterPro annotationAdd BLAST20

Sequence similaritiesi

Belongs to the RuvA family.UniRule annotationSAAS annotation

Family and domain databases

HAMAPiMF_00031. DNA_helic_RuvA. 1 hit.
InterProiView protein in InterPro
IPR013849. DNA_helicase_Holl-junc_RuvA_I.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR012340. NA-bd_OB-fold.
IPR000085. RuvA.
IPR010994. RuvA_2-like.
IPR011114. RuvA_C.
IPR036267. RuvA_C_sf.
PANTHERiPTHR33796. PTHR33796. 1 hit.
PfamiView protein in Pfam
PF07499. RuvA_C. 1 hit.
PF01330. RuvA_N. 1 hit.
SMARTiView protein in SMART
SM00278. HhH1. 2 hits.
SUPFAMiSSF46929. SSF46929. 1 hit.
SSF47781. SSF47781. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00084. ruvA. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A0R3L002-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIGKLKGLID SYGEDYVILD VGGVGYQVHC SSRTLQALPS PGEAAVLSIE
60 70 80 90 100
TYVREDQIKL FGFRTDTERE WFRLLQTVQG VGAKVALAVL STLPPAELAN
110 120 130 140 150
AIALRDKAAV SRTPGVGPKV AERIVSELKD KAPAFANVDP SVVHLAGAVD
160 170 180 190 200
DHRAPRPVTD AISALVNLGY GQPQAAAAIA AASRSAGENA ETAQLIRLGL

KELAK
Length:205
Mass (Da):21,579
Last modified:January 20, 2016 - v1
Checksum:i9370DD8E029E7450
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LLXX01000173 Genomic DNA. Translation: KRQ99228.1.
RefSeqiWP_057853880.1. NZ_LLXY01000178.1.

Genome annotation databases

EnsemblBacteriaiKRQ99228; KRQ99228; CP49_11560.

Similar proteinsi

Entry informationi

Entry nameiA0A0R3L002_9BRAD
AccessioniPrimary (citable) accession number: A0A0R3L002
Entry historyiIntegrated into UniProtKB/TrEMBL: January 20, 2016
Last sequence update: January 20, 2016
Last modified: October 25, 2017
This is version 16 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteomeImported