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Protein

Ribonuclease 3

Gene

rnc

Organism
Lactobacillus xiangfangensis
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage to 5'-phosphomonoester.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi48MagnesiumUniRule annotation1
Active sitei52UniRule annotation1
Metal bindingi121MagnesiumUniRule annotation1
Active sitei124UniRule annotation1
Metal bindingi124MagnesiumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonucleaseUniRule annotationSAAS annotation, Hydrolase, Nuclease, RNA-binding, rRNA-bindingUniRule annotationSAAS annotation
Biological processmRNA processingUniRule annotationSAAS annotation, rRNA processingUniRule annotationSAAS annotation, tRNA processingUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease 3UniRule annotation (EC:3.1.26.3UniRule annotation)
Alternative name(s):
Ribonuclease IIIUniRule annotation
Short name:
RNase IIIUniRule annotation
Gene namesi
Name:rncUniRule annotation
ORF Names:IV64_GL000538Imported
OrganismiLactobacillus xiangfangensisImported
Taxonomic identifieri942150 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
Proteomesi
  • UP000051783 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homodimer.UniRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 135RNase IIIInterPro annotationAdd BLAST130
Domaini161 – 230DRBMInterPro annotationAdd BLAST70

Sequence similaritiesi

Belongs to the ribonuclease III family.SAAS annotation

Family and domain databases

CDDicd00593. RIBOc. 1 hit.
Gene3Di1.10.1520.10. 1 hit.
HAMAPiMF_00104. RNase_III. 1 hit.
InterProiView protein in InterPro
IPR014720. dsRBD_dom.
IPR011907. RNase_III.
IPR000999. RNase_III_dom.
IPR036389. RNase_III_sf.
PfamiView protein in Pfam
PF00035. dsrm. 1 hit.
PF14622. Ribonucleas_3_3. 1 hit.
SMARTiView protein in SMART
SM00358. DSRM. 1 hit.
SM00535. RIBOc. 1 hit.
SUPFAMiSSF69065. SSF69065. 1 hit.
TIGRFAMsiTIGR02191. RNaseIII. 1 hit.
PROSITEiView protein in PROSITE
PS50137. DS_RBD. 1 hit.
PS50142. RNASE_3_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A0R2M976-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MITELAAMLK DRFGIVFNNP DLLAEAFTQA SYVNEHQDQN LKFYERVEFL
60 70 80 90 100
GDAVLELAVS EYLYKRYKDM PQGKLTRLRA AMVCEDSFAS FARECGFPQY
110 120 130 140 150
IRLGKGEQKA RAWERDSLLC DIFESFVGAL YLDQGREPVL KFVRQVIFPK
160 170 180 190 200
LDEGRFDGVF DYKTTLQEYL QRDGDVAIDY QLIEQDGPAN ERSYEIAVLA
210 220 230
DGKKIGQGWG HSKKEAEQSA AHQAYTQAQQ QD
Length:232
Mass (Da):26,612
Last modified:January 20, 2016 - v1
Checksum:iCD98632F4545CECD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JQCL01000080 Genomic DNA. Translation: KRO08450.1.
RefSeqiWP_057707044.1. NZ_JQCL01000080.1.

Genome annotation databases

EnsemblBacteriaiKRO08450; KRO08450; IV64_GL000538.
PATRICifig|942150.3.peg.551.

Similar proteinsi

Entry informationi

Entry nameiA0A0R2M976_9LACO
AccessioniPrimary (citable) accession number: A0A0R2M976
Entry historyiIntegrated into UniProtKB/TrEMBL: January 20, 2016
Last sequence update: January 20, 2016
Last modified: October 25, 2017
This is version 16 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteomeImported