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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Lactobacillus casei DSM 20011 = JCM 1134
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei140GTPUniRule annotation1
Binding sitei144GTPUniRule annotation1
Binding sitei188GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi22 – 26GTPUniRule annotation5
Nucleotide bindingi109 – 111GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotation
ORF Names:FC13_GL000378Imported
OrganismiLactobacillus casei DSM 20011 = JCM 1134Imported
Taxonomic identifieri1423732 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
Proteomesi
  • UP000051077 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotation
  • Note: Assembles at midcell at the inner surface of the cytoplasmic membrane.UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.UniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 206TubulinInterPro annotationAdd BLAST193
Domaini208 – 325Tubulin_CInterPro annotationAdd BLAST118

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Family and domain databases

CDDicd02201. FtsZ_type1. 1 hit.
Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
HAMAPiMF_00909. FtsZ. 1 hit.
InterProiView protein in InterPro
IPR000158. Cell_div_FtsZ.
IPR020805. Cell_div_FtsZ_CS.
IPR024757. FtsZ_C.
IPR008280. Tub_FtsZ_C.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR037103. Tubulin/FtsZ_C_sf.
IPR036525. Tubulin/FtsZ_GTPase_sf.
IPR003008. Tubulin_FtsZ_GTPase.
PfamiView protein in Pfam
PF12327. FtsZ_C. 1 hit.
PF00091. Tubulin. 1 hit.
PRINTSiPR00423. CELLDVISFTSZ.
SMARTiView protein in SMART
SM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
TIGRFAMsiTIGR00065. ftsZ. 1 hit.
PROSITEiView protein in PROSITE
PS01134. FTSZ_1. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A0R1FB50-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDFQMDAQNE KGANIKVIGV GGAGGNAINR MIAEDVKGVE FIAANTDLQA
60 70 80 90 100
LNASNAETKI QLGPKLTRGL GAGSNPEIGQ KAAEESEEAI GAALQGADMI
110 120 130 140 150
FVTAGMGGGS GTGAAPIVAK IAKDQGALTV GVVTRPFTFE GPKRAKNATE
160 170 180 190 200
GIAQLKEHVD TLVIIANNRL LEIVDKKTPM LEAFHAADNV LRQGVQGISD
210 220 230 240 250
LITSPGYVNL DFADVKTVMA NQGSALMGIG SATGENRTVE ATKKAISSPL
260 270 280 290 300
LEVNISGAKQ VLLNITGGPD LSLFEAQDAS QIVADSAKDD VNIIFGTSIN
310 320 330 340 350
EELGDEVVVT VIATGIEEDP RQEPSRRNVA KNRTTDQDNQ GGGYRPAYAD
360 370 380 390 400
SDANENRQAK SDDPFGNWDL RREPSKRQAP SGDDISNAKK KDFDIFENQT
410
NADDAGGDDQ PPFFKRRRQ
Length:419
Mass (Da):44,277
Last modified:January 20, 2016 - v1
Checksum:iBAFF2C0671F3CD62
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AZCO01000012 Genomic DNA. Translation: KRK16564.1.
RefSeqiWP_003570127.1. NZ_AZCO01000012.1.

Genome annotation databases

EnsemblBacteriaiKRK16564; KRK16564; FC13_GL000378.
PATRICifig|1423732.4.peg.389.

Similar proteinsi

Entry informationi

Entry nameiA0A0R1FB50_LACCA
AccessioniPrimary (citable) accession number: A0A0R1FB50
Entry historyiIntegrated into UniProtKB/TrEMBL: January 20, 2016
Last sequence update: January 20, 2016
Last modified: October 25, 2017
This is version 14 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteomeImported