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Protein

Phospho-N-acetylmuramoyl-pentapeptide-transferase

Gene

mraY

Organism
Rhizobium sp. Root1212
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan.UniRule annotation

Catalytic activityi

UDP-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala) + undecaprenyl phosphate = UMP + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol.UniRule annotation

Pathwayi: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferaseUniRule annotationImported
Biological processCell cycle, Cell divisionUniRule annotation, Cell shape, Cell wall biogenesis/degradationUniRule annotation, Peptidoglycan synthesisUniRule annotation

Enzyme and pathway databases

UniPathwayiUPA00219.

Names & Taxonomyi

Protein namesi
Recommended name:
Phospho-N-acetylmuramoyl-pentapeptide-transferaseUniRule annotation (EC:2.7.8.13UniRule annotation)
Alternative name(s):
UDP-MurNAc-pentapeptide phosphotransferaseUniRule annotation
Gene namesi
Name:mraYUniRule annotationImported
ORF Names:ASC86_09710Imported
OrganismiRhizobium sp. Root1212Imported
Taxonomic identifieri1736429 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium
Proteomesi
  • UP000052066 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei20 – 40HelicalUniRule annotationAdd BLAST21
Transmembranei73 – 90HelicalUniRule annotationAdd BLAST18
Transmembranei96 – 114HelicalUniRule annotationAdd BLAST19
Transmembranei134 – 158HelicalUniRule annotationAdd BLAST25
Transmembranei178 – 199HelicalUniRule annotationAdd BLAST22
Transmembranei206 – 225HelicalUniRule annotationAdd BLAST20
Transmembranei245 – 262HelicalUniRule annotationAdd BLAST18
Transmembranei269 – 288HelicalUniRule annotationAdd BLAST20
Transmembranei294 – 317HelicalUniRule annotationAdd BLAST24
Transmembranei344 – 363HelicalUniRule annotationAdd BLAST20

GO - Cellular componenti

Keywords - Cellular componenti

Cell membraneUniRule annotation, Membrane

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 4 family. MraY subfamily.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Family and domain databases

CDDicd06852. GT_MraY. 1 hit.
HAMAPiMF_00038. MraY. 1 hit.
InterProiView protein in InterPro
IPR000715. Glycosyl_transferase_4.
IPR003524. PNAcMuramoyl-5peptid_Trfase.
IPR018480. PNAcMuramoyl-5peptid_Trfase_CS.
PANTHERiPTHR22926. PTHR22926. 1 hit.
PfamiView protein in Pfam
PF00953. Glycos_transf_4. 1 hit.
PF10555. MraY_sig1. 1 hit.
TIGRFAMsiTIGR00445. mraY. 1 hit.
PROSITEiView protein in PROSITE
PS01347. MRAY_1. 1 hit.
PS01348. MRAY_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A0Q6SI83-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLIWLVELAD HIQFFNLFRY ITFRTGAALF TSALIVFLFG PKMISSLRVR
60 70 80 90 100
QGRGQPIRAD GPQTHFKKAG TPTMGGLMIL AGIVGSSLLW ADLSSVYVVS
110 120 130 140 150
TLLVTLGFGA IGFYDDYLKV TKQSDKGFSG KARLGLEFVF AAIAVFFMMR
160 170 180 190 200
AALSAGAAGS TFGSSLTFPF LKDFTLNLGY FFILFGGFVI VGAGNAVNLT
210 220 230 240 250
DGLDGLAIVP VMIAAASFGV IAYLAGNAVF ANYLQIHFVP GTGELAVILG
260 270 280 290 300
AVIGAGLGFL WFNAPPAAIF MGDTGSLALG GLIGTVAVAT KHEIVMIIIG
310 320 330 340 350
GLFVMETLSV IIQVFWFKRT GRRVFLMAPI HHHFEKKGWT ESQVVIRFWI
360
IAVILAMIGL STLKLR
Length:366
Mass (Da):39,314
Last modified:January 20, 2016 - v1
Checksum:i922F0622AAC7C2AC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LMDA01000012 Genomic DNA. Translation: KQV38471.1.
RefSeqiWP_056322370.1. NZ_LMDA01000012.1.

Genome annotation databases

EnsemblBacteriaiKQV38471; KQV38471; ASC86_09710.

Similar proteinsi

Entry informationi

Entry nameiA0A0Q6SI83_9RHIZ
AccessioniPrimary (citable) accession number: A0A0Q6SI83
Entry historyiIntegrated into UniProtKB/TrEMBL: January 20, 2016
Last sequence update: January 20, 2016
Last modified: September 27, 2017
This is version 12 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported