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Protein

Succinylglutamate desuccinylase

Gene

astE

Organism
Pseudomonas syringae pv. maculicola
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Transforms N2-succinylglutamate into succinate and glutamate.UniRule annotationSAAS annotation

Catalytic activityi

N-succinyl-L-glutamate + H2O = succinate + L-glutamate.UniRule annotationSAAS annotation

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

Pathwayi: L-arginine degradation via AST pathway

This protein is involved in step 5 of the subpathway that synthesizes L-glutamate and succinate from L-arginine.UniRule annotationSAAS annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. Arginine N-succinyltransferase (AC507_4674), Arginine N-succinyltransferase (AC507_4675), Arginine N-succinyltransferase (AC503_4683), Arginine N-succinyltransferase (AC505_2519), Arginine N-succinyltransferase (ALO84_01382), Arginine N-succinyltransferase (AC505_2518), Arginine N-succinyltransferase (ALO84_01383), Arginine N-succinyltransferase (AC504_4127), Arginine N-succinyltransferase (AC505_2007), Arginine N-succinyltransferase (AC504_4126), Arginine N-succinyltransferase (AC503_4682)
  2. N-succinylarginine dihydrolase (astB), N-succinylarginine dihydrolase (astB), N-succinylarginine dihydrolase (astB), N-succinylarginine dihydrolase (astB), N-succinylarginine dihydrolase (astB)
  3. no protein annotated in this organism
  4. N-succinylglutamate 5-semialdehyde dehydrogenase (astD), N-succinylglutamate 5-semialdehyde dehydrogenase (astD), N-succinylglutamate 5-semialdehyde dehydrogenase (astD), N-succinylglutamate 5-semialdehyde dehydrogenase (astD), N-succinylglutamate 5-semialdehyde dehydrogenase (astD), N-succinylglutamate 5-semialdehyde dehydrogenase (astD)
  5. Succinylglutamate desuccinylase (astE), Succinylglutamate desuccinylase (astE), Succinylglutamate desuccinylase (astE), Succinylglutamate desuccinylase (astE), Succinylglutamate desuccinylase (astE), Succinylglutamate desuccinylase (astE)
This subpathway is part of the pathway L-arginine degradation via AST pathway, which is itself part of Amino-acid degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes L-glutamate and succinate from L-arginine, the pathway L-arginine degradation via AST pathway and in Amino-acid degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi59ZincUniRule annotation1
Metal bindingi62ZincUniRule annotation1
Metal bindingi151ZincUniRule annotation1
Active sitei215UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotation
Biological processArginine metabolismUniRule annotationSAAS annotation
LigandMetal-bindingUniRule annotationSAAS annotation, ZincUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00185; UER00283.

Names & Taxonomyi

Protein namesi
Recommended name:
Succinylglutamate desuccinylaseUniRule annotationSAAS annotation (EC:3.5.1.96UniRule annotationSAAS annotation)
Gene namesi
Name:astEUniRule annotation
ORF Names:ALO84_01387Imported
OrganismiPseudomonas syringae pv. maculicolaImported
Taxonomic identifieri59511 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000050375 Componenti: Unassembled WGS sequence

Structurei

3D structure databases

ProteinModelPortaliA0A0P9U8T1.
SMRiA0A0P9U8T1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.UniRule annotationSAAS annotation

Family and domain databases

CDDicd03855. M14_ASTE. 1 hit.
HAMAPiMF_00767. Arg_catab_AstE. 1 hit.
InterProiView protein in InterPro
IPR007036. Aste_AspA.
IPR016681. SuccinylGlu_desuccinylase.
PfamiView protein in Pfam
PF04952. AstE_AspA. 1 hit.
PIRSFiPIRSF017020. AstE. 1 hit.
TIGRFAMsiTIGR03242. arg_catab_astE. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A0P9U8T1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLALGKLLEL TLAGREPAEK TQLTVEGVRM RWLAEGALEV RPPQARDNGT
60 70 80 90 100
DLLLSAGIHG NETAPIELLD ELIRSIARGD LKPRARILFL FGNPAAMRLG
110 120 130 140 150
ARYVEQDVNR LFNGRHEQSG GAEALRACEL ERLAASFFSL PDRYRLHYDL
160 170 180 190 200
HTAIRGSKIE QFALYPWKEG RQHSRFELAR LRAAGISAVL LQNKPSIVFS
210 220 230 240 250
AYTYEQLGAE AFTLELGKAR PFGQNRHVNL APLRLRLEQI IEGSEPQPDE
260 270 280 290 300
RLEGLQLFSV AREVIKRSDA FTFNLADDVE NFSELEKGYV LAEDVSDSRW
310 320 330
VVKEEGARII FPNPKVKNGL RAGIVIVPAD ADGLG
Length:335
Mass (Da):37,375
Last modified:January 20, 2016 - v1
Checksum:iE43CFD5829B97F3C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LJQR01000088 Genomic DNA. Translation: KPX73891.1.
RefSeqiWP_005767756.1. NZ_LJQR01000088.1.

Genome annotation databases

EnsemblBacteriaiKPX73891; KPX73891; ALO84_01387.
PATRICifig|59511.11.peg.3092.

Similar proteinsi

Entry informationi

Entry nameiA0A0P9U8T1_PSEYM
AccessioniPrimary (citable) accession number: A0A0P9U8T1
Entry historyiIntegrated into UniProtKB/TrEMBL: January 20, 2016
Last sequence update: January 20, 2016
Last modified: September 27, 2017
This is version 14 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteomeImported