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Protein

L-lactate dehydrogenase

Gene

lldD

Organism
Pseudomonas syringae pv. atrofaciens
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.UniRule annotationSAAS annotation

Catalytic activityi

(S)-lactate + an oxidized electron acceptor = pyruvate + a reduced electron acceptor.UniRule annotationSAAS annotation

Cofactori

FMNUniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei24SubstrateUniRule annotation1
Binding sitei106FMNUniRule annotation1
Binding sitei127FMNUniRule annotation1
Binding sitei129SubstrateUniRule annotation1
Binding sitei155FMNUniRule annotation1
Binding sitei164SubstrateUniRule annotation1
Binding sitei251FMNUniRule annotation1
Active sitei275Proton acceptorUniRule annotation1
Binding sitei278SubstrateUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi306 – 330FMNUniRule annotationAdd BLAST25

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotationSAAS annotation
LigandFlavoprotein, FMNUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
L-lactate dehydrogenaseUniRule annotationSAAS annotation (EC:1.1.-.-UniRule annotationSAAS annotation)
Gene namesi
Name:lldDUniRule annotation
ORF Names:ALO42_05136Imported
OrganismiPseudomonas syringae pv. atrofaciensImported
Taxonomic identifieri192087 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonasPseudomonas syringae
Proteomesi
  • UP000050311 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cell inner membrane SAAS annotation; Peripheral membrane protein SAAS annotation
  • Cell membrane UniRule annotation; Peripheral membrane protein UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membraneSAAS annotation, Cell membrane, Membrane

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 375FMN_dhInterPro annotationAdd BLAST363

Sequence similaritiesi

Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.UniRule annotationSAAS annotation

Family and domain databases

CDDicd02809. alpha_hydroxyacid_oxid_FMN. 1 hit.
Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_01559. L_lact_dehydr. 1 hit.
InterProiView protein in InterPro
IPR013785. Aldolase_TIM.
IPR012133. Alpha-hydoxy_acid_DH_FMN.
IPR000262. FMN-dep_DH.
IPR008259. FMN_hydac_DH_AS.
IPR020920. LldD.
PfamiView protein in Pfam
PF01070. FMN_dh. 1 hit.
PIRSFiPIRSF000138. Al-hdrx_acd_dh. 1 hit.
PROSITEiView protein in PROSITE
PS00557. FMN_HYDROXY_ACID_DH_1. 1 hit.
PS51349. FMN_HYDROXY_ACID_DH_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A0P9J126-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIISSASDYR AAAKRKLPRF LFDYIDGGAY AEHTLRANGS DLADISLRQR
60 70 80 90 100
VLKNVDNVSL ETRLFGESLA MPIVLSPVGL SGMYARRGEV QAAKAAANKR
110 120 130 140 150
IPFCLSTVSV CSIEEVASQS KQAIWFQLYV LKDRGFMKNA LERARAAGVT
160 170 180 190 200
TLVFTVDMPT PGARYRDAHS GMSGPYAAPR RILQAMTKPD WALNVGLLGR
210 220 230 240 250
PHDLGNISRY LGKATTLEDY VGWLANNFDP SISWKDLEWI REFWQGPMII
260 270 280 290 300
KGILDPQDAR DALSFGADGI VVSNHGGRQL DGALSTAKAL PPIVQAVGSD
310 320 330 340 350
LTVLADSGIR SGLDVVRMLA LGAKGVLLGR SMAYALGADG QRGVENMLDI
360 370 380
FAREMHVAMT LTGVTSIEQI DESILVKSAV
Length:380
Mass (Da):41,142
Last modified:January 20, 2016 - v1
Checksum:i91ED9C872F3568EC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LJPO01000156 Genomic DNA. Translation: KPW09092.1.
RefSeqiWP_024693440.1. NZ_LJPO01000156.1.

Genome annotation databases

EnsemblBacteriaiKPW09092; KPW09092; ALO42_05136.
PATRICifig|192087.3.peg.4282.

Similar proteinsi

Entry informationi

Entry nameiA0A0P9J126_PSESX
AccessioniPrimary (citable) accession number: A0A0P9J126
Entry historyiIntegrated into UniProtKB/TrEMBL: January 20, 2016
Last sequence update: January 20, 2016
Last modified: September 27, 2017
This is version 13 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteomeImported