Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Uracil-DNA glycosylase

Gene

ung

Organism
Streptomyces sp. CCM_MD2014
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.UniRule annotation

Catalytic activityi

Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei68Proton acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotation
Biological processDNA damage, DNA repairUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Uracil-DNA glycosylaseUniRule annotation (EC:3.2.2.27UniRule annotation)
Short name:
UDGUniRule annotation
Gene namesi
Name:ungUniRule annotation
ORF Names:NI25_33645Imported
OrganismiStreptomyces sp. CCM_MD2014Imported
Taxonomic identifieri1561022 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces
Proteomesi
  • UP000069932 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini53 – 212UDGInterPro annotationAdd BLAST160

Sequence similaritiesi

Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.UniRule annotationSAAS annotation

Phylogenomic databases

KOiK03648

Family and domain databases

CDDicd10027 UDG_F1, 1 hit
Gene3Di3.40.470.101 hit
HAMAPiMF_00148 UDG, 1 hit
InterProiView protein in InterPro
IPR002043 UDG_fam1
IPR018085 Ura-DNA_Glyclase_AS
IPR005122 Uracil-DNA_glycosylase-like
IPR036895 Uracil-DNA_glycosylase-like_sf
PANTHERiPTHR11264 PTHR11264, 1 hit
PfamiView protein in Pfam
PF03167 UDG, 1 hit
SMARTiView protein in SMART
SM00986 UDG, 1 hit
SUPFAMiSSF52141 SSF52141, 1 hit
PROSITEiView protein in PROSITE
PS00130 U_DNA_GLYCOSYLASE, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0N6ZT89-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPRPLNEIV EAGWAKALEP VAGRITAMGE FLRAEIAAGR TYLPAGANVL
60 70 80 90 100
RAFQQPFDDV RVLIVGQDPY PTPGHAVGLS FSVAPEVRPL PGSLVNIFRE
110 120 130 140 150
LNTDLNLPHP SNGDLTPWTR QGVLLLNRAL TTAPRKPAAH RGKGWEEVTE
160 170 180 190 200
QAIRALAARG KPMVSILWGR DARNLRPLLG DLPAVESAHP SPMSADRGFF
210 220
GSRPFSRAND LLMRLGGQPV DWRLP
Length:225
Mass (Da):24,479
Last modified:January 20, 2016 - v1
Checksum:i1CE591DFEB761FD4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009754 Genomic DNA Translation: AIV37854.1
RefSeqiWP_061446098.1, NZ_CP009754.1

Genome annotation databases

EnsemblBacteriaiAIV37854; AIV37854; NI25_33645
KEGGistrd:NI25_33645
PATRICifig|1561022.5.peg.7004

Similar proteinsi

Entry informationi

Entry nameiA0A0N6ZT89_9ACTN
AccessioniPrimary (citable) accession number: A0A0N6ZT89
Entry historyiIntegrated into UniProtKB/TrEMBL: January 20, 2016
Last sequence update: January 20, 2016
Last modified: March 28, 2018
This is version 20 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported