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Protein

Chromosomal replication initiator protein DnaA

Gene

dnaA

Organism
Novosphingobium sp. AAP93
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.UniRule annotationSAAS annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi201 – 208ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation
Biological processDNA replicationUniRule annotationSAAS annotation
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chromosomal replication initiator protein DnaAUniRule annotationSAAS annotation
Gene namesi
Name:dnaAUniRule annotation
ORF Names:IP83_19130Imported
OrganismiNovosphingobium sp. AAP93Imported
Taxonomic identifieri1523427 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaSphingomonadalesSphingomonadaceaeNovosphingobium
Proteomesi
  • UP000037906 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini193 – 341AAAInterPro annotationAdd BLAST149
Domaini405 – 474Bac_DnaA_CInterPro annotationAdd BLAST70

Sequence similaritiesi

Belongs to the DnaA family.UniRule annotationSAAS annotation

Family and domain databases

CDDicd06571. Bac_DnaA_C. 1 hit.
Gene3Di1.10.1750.10. 1 hit.
HAMAPiMF_00377. DnaA_bact. 1 hit.
InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR001957. Chromosome_initiator_DnaA.
IPR020591. Chromosome_initiator_DnaA-like.
IPR018312. Chromosome_initiator_DnaA_CS.
IPR013317. DnaA.
IPR013159. DnaA_C.
IPR024633. DnaA_N_dom.
IPR027417. P-loop_NTPase.
IPR010921. Trp_repressor/repl_initiator.
PANTHERiPTHR30050:SF2. PTHR30050:SF2. 1 hit.
PfamiView protein in Pfam
PF00308. Bac_DnaA. 1 hit.
PF08299. Bac_DnaA_C. 1 hit.
PF11638. DnaA_N. 1 hit.
PRINTSiPR00051. DNAA.
SMARTiView protein in SMART
SM00382. AAA. 1 hit.
SM00760. Bac_DnaA_C. 1 hit.
SUPFAMiSSF48295. SSF48295. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00362. DnaA. 1 hit.
PROSITEiView protein in PROSITE
PS01008. DNAA. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A0N1BIQ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKMDDYGSGG RGAAAQTADA APGRRGRDSA MIEDQEALDL AADWADISQG
60 70 80 90 100
LKKDLGPQLH SQWIKPIQVG TFCKETGTLD LFLPTEFSAN WVADRFADRL
110 120 130 140 150
SLAWKIARSE VRQVRITVHP RRRAMPELRM GGLPANDTGP LPTAARQPAV
160 170 180 190 200
PLSADAAVTG LDPSLTFAEF VSGSANVLAV NAAQRMAALE TPQFSPLYLK
210 220 230 240 250
GATGQGKTHL LHAIGHAYAA ARPGARIFYC SAERFMIEFV QAMRSNEMLE
260 270 280 290 300
FKARLRGFDL LLVDDIQFII GKASTQEEFL HTIDALMSAG KRLVVAADRA
310 320 330 340 350
PQALDGVEQR LLSRLSMGLV ADIQPADIDL RRKILEHRLA RFTSTQVPAD
360 370 380 390 400
VIEFLARTIN RNVRELVGGL NKLIAYAQLT GQPVSLQLAE EQLTDILSAN
410 420 430 440 450
RRRITIDEIQ RMVCQFYRVD RTEMASKRRA RAVVRPRQVA MYLAKVLTPR
460 470 480 490
SYPEIGRKFG GRDHSTVIHA VRLIEELRTR DADMDGDVRT LLRQLED
Length:497
Mass (Da):55,130
Last modified:December 9, 2015 - v1
Checksum:i280A6D7DA423E6D4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LJHZ01000136 Genomic DNA. Translation: KPF78027.1.
RefSeqiWP_054123825.1. NZ_LJHZ01000136.1.

Genome annotation databases

EnsemblBacteriaiKPF78027; KPF78027; IP83_19130.
PATRICifig|1523427.4.peg.1057.

Similar proteinsi

Entry informationi

Entry nameiA0A0N1BIQ1_9SPHN
AccessioniPrimary (citable) accession number: A0A0N1BIQ1
Entry historyiIntegrated into UniProtKB/TrEMBL: December 9, 2015
Last sequence update: December 9, 2015
Last modified: October 25, 2017
This is version 16 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported