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Protein

Chromosomal replication initiator protein DnaA

Gene

dnaA

Organism
Bacillus campisalis
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.UniRule annotationSAAS annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi152 – 159ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation
Biological processDNA replicationUniRule annotationSAAS annotation
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chromosomal replication initiator protein DnaAUniRule annotationSAAS annotation
Gene namesi
Name:dnaAUniRule annotation
ORF Names:WQ57_17120Imported
OrganismiBacillus campisalisImported
Taxonomic identifieri1408103 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000034166 Componenti: Unassembled WGS sequence

Subcellular locationi

A0A0M2SRV2:
  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini144 – 272AAAInterPro annotationAdd BLAST129
Domaini356 – 425Bac_DnaA_CInterPro annotationAdd BLAST70

Sequence similaritiesi

Belongs to the DnaA family.UniRule annotationSAAS annotation

Family and domain databases

CDDicd06571. Bac_DnaA_C. 1 hit.
Gene3Di1.10.1750.10. 1 hit.
HAMAPiMF_00377. DnaA_bact. 1 hit.
InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR001957. Chromosome_initiator_DnaA.
IPR020591. Chromosome_initiator_DnaA-like.
IPR018312. Chromosome_initiator_DnaA_CS.
IPR013317. DnaA.
IPR013159. DnaA_C.
IPR024633. DnaA_N_dom.
IPR027417. P-loop_NTPase.
IPR010921. Trp_repressor/repl_initiator.
PANTHERiPTHR30050:SF2. PTHR30050:SF2. 1 hit.
PfamiView protein in Pfam
PF00308. Bac_DnaA. 1 hit.
PF08299. Bac_DnaA_C. 1 hit.
PF11638. DnaA_N. 1 hit.
PRINTSiPR00051. DNAA.
SMARTiView protein in SMART
SM00382. AAA. 1 hit.
SM00760. Bac_DnaA_C. 1 hit.
SUPFAMiSSF48295. SSF48295. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00362. DnaA. 1 hit.
PROSITEiView protein in PROSITE
PS01008. DNAA. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A0M2SRV2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENIADLWNN ALSKIEKKIS KPSFDTWLKS TKAHSLQGDT LTITAPNEFA
60 70 80 90 100
RDWLEERYSQ LISSILYEIT GEELGIKFII PQNQNDEEFS VPVPPKKAIK
110 120 130 140 150
DDDQHDLPNN MLNPKYTFDT FVIGSGNRFA HAASLAVAEA PAKAYNPLFI
160 170 180 190 200
YGGVGLGKTH LMHAIGHYVQ DHNPSAKVVY LSSEKFTNEF INSIRDNKAV
210 220 230 240 250
EFRNKYRKVD VLLIDDIQFL AGKESTQEEF FHTFNTLHEE SKQIIISSDR
260 270 280 290 300
PPKEIPTLED RLRSRFEWGL ITDITPPDLE TRIAILRKKA KAEGLDIPNE
310 320 330 340 350
VMLYIANQID SNIRELEGAL IRVVAFSSLI NKDINADLAA EALKNIIPSS
360 370 380 390 400
KPKVITILDI QRTVGQHFNV KLEDFKAKKR TKSVAFPRQI AMYLSRELTD
410 420 430 440
FSLPKIGEEF GGRDHTTVIH AHEKISKLLS TDSALQRQLR DIHEELKI
Length:448
Mass (Da):50,901
Last modified:November 11, 2015 - v1
Checksum:i54E8D8E9C85FD19F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LAYY01000021 Genomic DNA. Translation: KKK36873.1.
RefSeqiWP_046524985.1. NZ_LAYY01000021.1.

Genome annotation databases

EnsemblBacteriaiKKK36873; KKK36873; WQ57_17120.
PATRICifig|1408103.3.peg.3809.

Similar proteinsi

Entry informationi

Entry nameiA0A0M2SRV2_9BACI
AccessioniPrimary (citable) accession number: A0A0M2SRV2
Entry historyiIntegrated into UniProtKB/TrEMBL: November 11, 2015
Last sequence update: November 11, 2015
Last modified: October 25, 2017
This is version 16 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported