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Protein

Aconitate hydratase, mitochondrial

Gene

DI49_2832

Organism
Saccharomyces eubayanus (Yeast)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Cofactori

[4Fe-4S] clusterUniRule annotationNote: Binds 1 [4Fe-4S] cluster per subunit.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotation
LigandIron, Iron-sulfurUniRule annotation, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Aconitate hydratase, mitochondrialUniRule annotation (EC:4.2.1.-UniRule annotation)
Short name:
AconitaseUniRule annotation
Gene namesi
ORF Names:DI49_2832Imported
OrganismiSaccharomyces eubayanus (Yeast)Imported
Taxonomic identifieri1080349 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000050240 Componenti: Chromosome X

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

MitochondrionUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini58 – 505AconitaseInterPro annotationAdd BLAST448
Domaini586 – 713Aconitase_CInterPro annotationAdd BLAST128

Sequence similaritiesi

Belongs to the aconitase/IPM isomerase family.UniRule annotation

Keywords - Domaini

Transit peptideUniRule annotation

Family and domain databases

Gene3Di3.20.19.10. 1 hit.
3.30.499.10. 2 hits.
3.40.1060.10. 1 hit.
InterProiView protein in InterPro
IPR015931. Acnase/IPM_dHydase_lsu_aba_1/3.
IPR001030. Acoase/IPM_deHydtase_lsu_aba.
IPR015928. Aconitase/3IPM_dehydase_swvl.
IPR015932. Aconitase/IPMdHydase_lsu_aba_2.
IPR018136. Aconitase_4Fe-4S_BS.
IPR006248. Aconitase_mito-like.
IPR000573. AconitaseA/IPMdHydase_ssu_swvl.
PfamiView protein in Pfam
PF00330. Aconitase. 1 hit.
PF00694. Aconitase_C. 1 hit.
PRINTSiPR00415. ACONITASE.
SUPFAMiSSF52016. SSF52016. 1 hit.
SSF53732. SSF53732. 1 hit.
TIGRFAMsiTIGR01340. aconitase_mito. 1 hit.
PROSITEiView protein in PROSITE
PS00450. ACONITASE_1. 1 hit.
PS01244. ACONITASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A0L8RGC2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSSANRFYI KRHLASHANM FPSVSKQFQT KVPPYAKLLT NLDKIKQITN
60 70 80 90 100
NAPLTLAEKI LYSHLCDPEE SITSSDLSTV RGNKYLKLNP DRVAMQDASA
110 120 130 140 150
QMALLQFMTT GLNQTSVPAS IHCDHLIVGK DGEAQDLPSS IATNQEVFDF
160 170 180 190 200
LESCAKRYGI QFWGPGSGII HQIVLENFSA PGLMMLGTDS HTPNAGGLGA
210 220 230 240 250
IAIGVGGADA VDALTGTPWE LKAPKILGVK LTGRLNGWST PKDVITKIAG
260 270 280 290 300
LLTVRGGTGY IIEYFGEGVS TLSCTGMATI CNMGAEIGAT TSTFPYQEAH
310 320 330 340 350
KRYLQATNRS EVADAADVAL NEYGFLRADE GAQYEKVIEI DLSAIEPHVN
360 370 380 390 400
GPFTPDLSTP ISQYAERSLQ ENWPQKVSAG LIGSCTNSSY QDMSRVVDLV
410 420 430 440 450
KQASKVGLKP RIPFFVTPGS EQIRATLERD GIIDIFQENG AKVLANACGP
460 470 480 490 500
CIGQWNREDV SKTSKEANTI FTSFNRNFRA RNDGNRNTMN FLTSPEIVTA
510 520 530 540 550
MSYSGNAQFN PLTDSIKLPN GEDFKFQPPN GDELPKRGFE HGRDKFYPEL
560 570 580 590 600
DPKPNSNIEI KVDPKSDRLQ LLDPFKAWNG KELKTNVLLK VEGKCTTDHI
610 620 630 640 650
SAAGVWLKYK GHLENISYNT LIGAQNKETG EVNKAYDLDG TEYDIPGLMM
660 670 680 690 700
KWKSDNRPWT VIAEHNYGEG SAREHAALSP RFLGGEILLV KSFARIHETN
710 720 730 740 750
LKKQGMLPLT FATESDYDKI SSGDILETLN LADMIAKDGN NGGEIDVKIT
760 770 780
KPNGDSFIIK AKHTMSKDQI DFFKAGSAIN HIGNIRRGE
Length:789
Mass (Da):86,458
Last modified:November 11, 2015 - v1
Checksum:i5EA52BA205ED1D8B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JMCK01000010 Genomic DNA. Translation: KOG98427.1.
RefSeqiXP_018221145.1. XM_018365939.1.

Genome annotation databases

EnsemblFungiiKOG98427; KOG98427; DI49_2832.
GeneIDi28931969.

Similar proteinsi

Entry informationi

Entry nameiA0A0L8RGC2_SACEU
AccessioniPrimary (citable) accession number: A0A0L8RGC2
Entry historyiIntegrated into UniProtKB/TrEMBL: November 11, 2015
Last sequence update: November 11, 2015
Last modified: June 7, 2017
This is version 8 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteomeImported