Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Streptomyces resistomycificus
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotationSAAS annotation

Pathwayi: gluconeogenesis

This protein is involved in the pathway gluconeogenesis, which is part of Carbohydrate biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway gluconeogenesis and in Carbohydrate biosynthesis.

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotationSAAS annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi), Glucose-6-phosphate isomerase (pgi)
  3. ATP-dependent 6-phosphofructokinase (pfkA), Pyrophosphate--fructose 6-phosphate 1-phosphotransferase (pfp), ATP-dependent 6-phosphofructokinase (pfkA)
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei390UniRule annotation1
Active sitei514UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
Biological processGluconeogenesisUniRule annotationSAAS annotation, GlycolysisUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
ORF Names:ADK37_21690Imported, AQJ84_28970Imported
OrganismiStreptomyces resistomycificusImported
Taxonomic identifieri67356 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces
Proteomesi
  • UP000037251 Componenti: Unassembled WGS sequence
  • UP000052992 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotationSAAS annotation

Family and domain databases

CDDicd05015. SIS_PGI_1. 1 hit.
cd05016. SIS_PGI_2. 1 hit.
Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase. 1 hit.
InterProiView protein in InterPro
IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
IPR035476. SIS_PGI_1.
IPR035482. SIS_PGI_2.
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiView protein in Pfam
PF00342. PGI. 1 hit.
PRINTSiPR00662. G6PISOMERASE.
PROSITEiView protein in PROSITE
PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A0L8L695-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNADGRTRLN ETPEWTALAR HREELGDVRL RELFAADPGR GSGYTMRVGD
60 70 80 90 100
LYVDYSKQLV TDETLRLLRE LAARADVFGL RDAMFRGERI NTTEDRAVLH
110 120 130 140 150
TALRSSRDAV VEVDGENVVP GVHAVLDKMA DFAERVRSGE WTGHTGKRIR
160 170 180 190 200
NVVNVGIGGS DLGPAMAYEA LRAYTDRDLT VRFVSNVDGA DLHEAVRDLD
210 220 230 240 250
AAETLFVIAS KTFTTIETIT NATSARDWLL TELKAGQDAV AKHFVALSTN
260 270 280 290 300
AGKVSEFGID TANMFEFWDW VGGRYSFDSA IGLSLMVAVG PERFREMLEG
310 320 330 340 350
FRLVDEHFRT APAEANVPLL LGLLGVWYGN FFGAQSHAVL PYSHYLSKFT
360 370 380 390 400
AYLQQLDMES NGKSVDRDGN PVDWQTGPVV WGTPGTNGQH AYYQLIHQGT
410 420 430 440 450
KLIPADFIGF AEPVADLQPG LVAQHDLLMA NFFAQTQALA FGKTAEEVRA
460 470 480 490 500
EGAPEELVPH KTFRGNRPTT TILARALTPS VLGQLIALYE HKVFVQGAIW
510 520 530 540 550
NIDSFDQWGV ELGKVLAKRV EPALTEGAEV PGLDASTKAL VAAYRELRGR

Q
Length:551
Mass (Da):60,682
Last modified:November 11, 2015 - v1
Checksum:i4511A7B144631E91
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LGUS01000170 Genomic DNA. Translation: KOG33733.1.
LMWZ01000025 Genomic DNA. Translation: KUN93953.1.
RefSeqiWP_053191918.1. NZ_LGUS01000170.1.

Genome annotation databases

EnsemblBacteriaiKOG33733; KOG33733; ADK37_21690.
KUN93953; KUN93953; AQJ84_28970.
PATRICifig|67356.5.peg.4616.

Similar proteinsi

Entry informationi

Entry nameiA0A0L8L695_9ACTN
AccessioniPrimary (citable) accession number: A0A0L8L695
Entry historyiIntegrated into UniProtKB/TrEMBL: November 11, 2015
Last sequence update: November 11, 2015
Last modified: September 27, 2017
This is version 13 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteomeImported