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Protein

Phosphopentomutase

Gene

deoB

Organism
Methylobacterium sp. ARG-1
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Phosphotransfer between the C1 and C5 carbon atoms of pentose.UniRule annotationSAAS annotation

Catalytic activityi

2-deoxy-alpha-D-ribose 1-phosphate = 2-deoxy-alpha-D-ribose 5-phosphate.UniRule annotationSAAS annotation
Alpha-D-ribose 1-phosphate = D-ribose 5-phosphate.UniRule annotationSAAS annotation

Cofactori

Mn2+UniRule annotationNote: Binds 1 or 2 manganese ions.UniRule annotation

Pathwayi: 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route II).UniRule annotationSAAS annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. Phosphopentomutase (deoB)
  2. no protein annotated in this organism
  3. Ribose 1,5-bisphosphate phosphokinase PhnN (phnN)
This subpathway is part of the pathway 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis, which is itself part of Metabolic intermediate biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route II), the pathway 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis and in Metabolic intermediate biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi10ManganeseUniRule annotation1
Metal bindingi310ManganeseUniRule annotation1
Metal bindingi346ManganeseUniRule annotation1
Metal bindingi347ManganeseUniRule annotation1
Metal bindingi358ManganeseUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotation
LigandManganeseUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00087; UER00173.

Names & Taxonomyi

Protein namesi
Recommended name:
PhosphopentomutaseUniRule annotationSAAS annotation (EC:5.4.2.7UniRule annotationSAAS annotation)
Alternative name(s):
PhosphodeoxyribomutaseUniRule annotation
Gene namesi
Name:deoBUniRule annotation
ORF Names:AKJ13_21735Imported
OrganismiMethylobacterium sp. ARG-1Imported
Taxonomic identifieri1692501 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesMethylobacteriaceaeMethylobacterium
Proteomesi
  • UP000036734 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 396MetalloenzymeInterPro annotationAdd BLAST394

Sequence similaritiesi

Belongs to the phosphopentomutase family.UniRule annotationSAAS annotation

Family and domain databases

CDDicd16009. PPM. 1 hit.
Gene3Di3.30.70.1250. 1 hit.
3.40.720.10. 1 hit.
HAMAPiMF_00740. Phosphopentomut. 1 hit.
InterProiView protein in InterPro
IPR017849. Alkaline_Pase-like_a/b/a.
IPR017850. Alkaline_phosphatase_core_sf.
IPR010045. DeoB.
IPR006124. Metalloenzyme.
IPR024052. Phosphopentomutase_DeoB_cap_sf.
PANTHERiPTHR21110. PTHR21110. 1 hit.
PfamiView protein in Pfam
PF01676. Metalloenzyme. 1 hit.
PIRSFiPIRSF001491. Ppentomutase. 1 hit.
SUPFAMiSSF143856. SSF143856. 1 hit.
SSF53649. SSF53649. 2 hits.
TIGRFAMsiTIGR01696. deoB. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A0L6J4A3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARALLIVLD SVGIGGAPDA ATYGDAGSDT LGHIAEACAA GRGDRAGLRA
60 70 80 90 100
GPLRLPHLAA LGLGLAAAGA SGRIPPNLAP QGDPRGAYGH AVETAAGKDT
110 120 130 140 150
PSGHWEITGL PLPEPWGHFP DTRPAFPPAL VEALIAEGGL PGILGDRHAP
160 170 180 190 200
GVAIIDALGA EHVRTGKPIC YTSADSVFQI AAHEETFGLE RLYALCRVAR
210 220 230 240 250
RLCDPYRICR VIARPFVGSA EAGFRRTGNR KDFAVAPPGR TLLDRAEAEG
260 270 280 290 300
RAVVSVGKIG DIFAHRATGR EIKPGANAAC LQAGLDALTD LPEGGLIFVN
310 320 330 340 350
LVDFDTEHGH RRDVPGYAAE LEAFDARVPE ILAALQPGDL AVITADHGND
360 370 380 390 400
PTWTGTDHTR EQVPVLAFGP GIAPRSIGRR DTFADIGATL AAHLGLSWDG

AGRVFL
Length:406
Mass (Da):42,200
Last modified:November 11, 2015 - v1
Checksum:iD73BA005A4DD800F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LHCD01000027 Genomic DNA. Translation: KNY20618.1.
RefSeqiWP_050735226.1. NZ_LHCD01000027.1.

Genome annotation databases

EnsemblBacteriaiKNY20618; KNY20618; AKJ13_21735.
PATRICifig|1692501.3.peg.2984.

Similar proteinsi

Entry informationi

Entry nameiA0A0L6J4A3_9RHIZ
AccessioniPrimary (citable) accession number: A0A0L6J4A3
Entry historyiIntegrated into UniProtKB/TrEMBL: November 11, 2015
Last sequence update: November 11, 2015
Last modified: November 22, 2017
This is version 16 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteomeImported