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Protein

5'-deoxynucleotidase VC274080_022019

Gene

VC274080_022019

Organism
Vibrio cholerae 2740-80
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.UniRule annotationSAAS annotation

Catalytic activityi

A 2'-deoxyribonucleoside 5'-monophosphate + H2O = a 2'-deoxyribonucleoside + phosphate.UniRule annotationSAAS annotation

Cofactori

a divalent metal cationUniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei18Appears to be important in orienting the phosphate for catalysisUniRule annotation1
Metal bindingi33Divalent metal cation; via tele nitrogenUniRule annotation1
Binding sitei33SubstrateUniRule annotation1
Metal bindingi68Divalent metal cation; via tele nitrogenUniRule annotation1
Metal bindingi69Divalent metal cationUniRule annotation1
Binding sitei69SubstrateUniRule annotation1
Metal bindingi137Divalent metal cationUniRule annotation1
Binding sitei137SubstrateUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotation
LigandMetal-bindingUniRule annotationSAAS annotation, Nucleotide-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
5'-deoxynucleotidase VC274080_022019UniRule annotation (EC:3.1.3.89UniRule annotation)
Alternative name(s):
5'-deoxyribonucleotidaseUniRule annotation
Nucleoside 5'-monophosphate phosphohydrolaseUniRule annotation
Gene namesi
ORF Names:VC274080_022019Imported
OrganismiVibrio cholerae 2740-80Imported
Taxonomic identifieri412614 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
Proteomesi
  • UP000003017 Componenti: Unassembled WGS sequence

Subcellular locationi

A0A0K9UZH7:
  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homodimer.UniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliA0A0K9UZH7.
SMRiA0A0K9UZH7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 151HDcInterPro annotationAdd BLAST126

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni18 – 19Substrate bindingUniRule annotation2
Regioni77 – 80Substrate bindingUniRule annotation4

Sequence similaritiesi

Belongs to the 5DNU family.UniRule annotationSAAS annotation

Family and domain databases

HAMAPiMF_01100. 5DNU. 1 hit.
InterProiView protein in InterPro
IPR003607. HD/PDEase_dom.
IPR006674. HD_domain.
IPR022971. YfbR.
PfamiView protein in Pfam
PF13023. HD_3. 1 hit.
SMARTiView protein in SMART
SM00471. HDc. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A0K9UZH7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQESHFFAHL ARMKLIQRWP LMRSISSENI SEHSLQVAFV AHALAVIKNK
60 70 80 90 100
KFGGTLNPER IALLAMYHDT SEVLTGDLPT PIKYFNPEIA KEYKKIEAAA
110 120 130 140 150
ERRLLDMLPE ELRDDFRPFL ISNTADPDES AIVKQADAIC AYLKCLEELS
160 170 180 190
AGNHEYAQAK KRLDVTLRER HSEEMAYFLQ TFAPSFELTL DEIS
Length:194
Mass (Da):22,213
Last modified:November 11, 2015 - v1
Checksum:i360F33D7894E1A4A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAUT02000001 Genomic DNA. Translation: KNA61679.1.
RefSeqiWP_001158196.1. NZ_MIKI01000094.1.

Genome annotation databases

EnsemblBacteriaiKNA61679; KNA61679; VC274080_022019.

Similar proteinsi

Entry informationi

Entry nameiA0A0K9UZH7_VIBCL
AccessioniPrimary (citable) accession number: A0A0K9UZH7
Entry historyiIntegrated into UniProtKB/TrEMBL: November 11, 2015
Last sequence update: November 11, 2015
Last modified: September 27, 2017
This is version 12 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteomeImported