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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Francisella persica ATCC VR-331
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetaseUniRule annotationImported, Ligase
Biological processProtein biosynthesisUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
ORF Names:ACH24_01710Imported, FSC845_04510Imported
OrganismiFrancisella persica ATCC VR-331Imported
Taxonomic identifieri1086726 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesFrancisellaceaeFrancisella

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 86Arg_tRNA_synt_NInterPro annotationAdd BLAST86
Domaini459 – 583DALR_1InterPro annotationAdd BLAST125

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi122 – 132"HIGH" regionUniRule annotationAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

KOiK01887.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR036695. Arg-tRNA-synth_N_sf.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A0K2JQL0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIENYLSEI LAKVFQKLGY AESFAKVVTS TREGVGHFQC NGAMPLAKFV
60 70 80 90 100
KKPPFIIAEE IIEHIDAKDV FAKLEVAKPG FINMTLAPRF LANTTDKFLN
110 120 130 140 150
SVKFGAQNYL SSKKVVLDFG GPNVAKPMHV GHIRSALLGD ALQRIHRFYD
160 170 180 190 200
DIVVSDVHLG DWGTQMGMLI EEIKLQSPQL AYFDETYTGE YPSESPVTVQ
210 220 230 240 250
ELAEIYPRAS KRCKSDIIEM EKVRLATFEL QQGRRGYVAL WQHFVKISID
260 270 280 290 300
AIKKDFDSLD VHFDLWLGES DANKFVNEMI NYFKANNFIY EDQGAWIINT
310 320 330 340 350
NKDGVPPLIV IKKDGGFMYG TTDLATLWQR SRDLDPDEII YVVDKRQSLH
360 370 380 390 400
FKQVFSVAER TKVVSEKCKL KHVAFGTVNG KDGRPFKTRE GGVMHLADLI
410 420 430 440 450
SQAKEYAKNR MPDEHDDSII DQVAMATIKF GDLVNNYAND YIFDLEKFAQ
460 470 480 490 500
HEGKTGPYLL YTAVRAKSIL RKIFGENYDI QSLILIKDYK VVNAHNEHEE
510 520 530 540 550
KLQLQLIQFP IAVQRAYENS QPHHICEYAY SLANSFNKFY VNCPIINLDD
560 570 580
KSFKKARIAL CMATVKAMTI ASDLLGISIP ERM
Length:583
Mass (Da):66,323
Last modified:November 11, 2015 - v1
Checksum:iE583E5E987F37AB9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP012505 Genomic DNA. Translation: ALB01490.1.
CP013022 Genomic DNA. Translation: ANH77781.1.
RefSeqiWP_064460906.1. NZ_CP013022.1.

Genome annotation databases

KEGGifper:ACH24_01710.
PATRICifig|1086726.6.peg.414.

Similar proteinsi

Entry informationi

Entry nameiA0A0K2JQL0_9GAMM
AccessioniPrimary (citable) accession number: A0A0K2JQL0
Entry historyiIntegrated into UniProtKB/TrEMBL: November 11, 2015
Last sequence update: November 11, 2015
Last modified: November 22, 2017
This is version 18 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)