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Protein

Poly(A) polymerase catalytic subunit

Gene

PAPL

Organism
Camelpox virus
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Polymerase that creates the 3'-poly(A) tail of mRNA's.UniRule annotation

Catalytic activityi

ATP + RNA(n) = diphosphate + RNA(n+1).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei202UniRule annotation1
Active sitei204UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferaseImported, Transferase
Biological processmRNA processingUniRule annotation, TranscriptionUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Poly(A) polymerase catalytic subunitUniRule annotation (EC:2.7.7.19UniRule annotation)
Alternative name(s):
Poly(A) polymerase large subunitUniRule annotation
Gene namesi
Name:PAPLImported
ORF Names:TT95_00064Imported
OrganismiCamelpox virusImported
Taxonomic identifieri28873 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stagePoxviridaeChordopoxvirinaeOrthopoxvirus
Proteomesi
  • UP000157591 Componenti: Genome

Interactioni

Subunit structurei

Heterodimer of a large (catalytic) subunit and a small (regulatory) subunit.UniRule annotation

Structurei

3D structure databases

SMRiA0A0K1LD58.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini15 – 117Pox_polyA_pol_NInterPro annotationAdd BLAST103
Domaini132 – 279Pox_polyA_polInterPro annotationAdd BLAST148
Domaini282 – 478Pox_polyA_pol_CInterPro annotationAdd BLAST197

Sequence similaritiesi

Belongs to the poxviridae poly(A) polymerase catalytic subunit family.UniRule annotation

Family and domain databases

InterProiView protein in InterPro
IPR037265. PolyA_pol_cat_sf.
IPR024231. Pox_polyA_pol_nucTrfase.
IPR004976. Poxviridae_polyA_pol_cat.
IPR024397. Poxvirus_polyA_pol_cat_C.
IPR024398. Poxvirus_polyA_pol_cat_N.
PfamiView protein in Pfam
PF03296. Pox_polyA_pol. 1 hit.
PF12629. Pox_polyA_pol_C. 1 hit.
PF12630. Pox_polyA_pol_N. 1 hit.
PIRSFiPIRSF015693. VAC-48L_nuct. 2 hits.
SUPFAMiSSF160957. SSF160957. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A0K1LD58-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNRNPDHNTL PNITLKIIET YLGRLPSVNE YYMLKLQTRN IQKITVFNKD
60 70 80 90 100
IFVSLVKKNK KRFFSDVDTS ASEIKDRILS YFSKQTQTYN IGKLFTIIEL
110 120 130 140 150
QSVLVTTYTD ILGVLTIKAP NVISSKISYN VTSMEELARD MLNSMNVAVI
160 170 180 190 200
DKAKVMGRHN VSSLVKNVNK LMEEYLRRHN KSCICYGSYS LYLINPNIRY
210 220 230 240 250
GDIDILQTNS RTFLIDLAFL IKFITGNNII LSKIPYLRNY MVIKDENDNH
260 270 280 290 300
IIDSFNIRQD TMNVVPKIFI DNIYIVDPTF QLLNMIKMFS QIDRLEDLSK
310 320 330 340 350
DPEKFNARMA TMLEYVRYTH GIVFDGKRNN MPMKCIIDEN NRIVTVTTKD
360 370 380 390 400
YFSFKKCLAY LDENVLSSDI LDLNADTSCD FESVTNSVYL IHDNIMYTYF
410 420 430 440 450
SNTILLSDKG KVHEISARGL CAHILLYQML TSGEYKQCLS DLLNSMMNRD
460 470
KIPIYSHTER DKKPGRHGFI NIEKDIIVF
Length:479
Mass (Da):55,583
Last modified:November 11, 2015 - v1
Checksum:i4BA5329DAE217831
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KP768318 Genomic DNA. Translation: AKU40422.1.

Similar proteinsi

Entry informationi

Entry nameiA0A0K1LD58_9POXV
AccessioniPrimary (citable) accession number: A0A0K1LD58
Entry historyiIntegrated into UniProtKB/TrEMBL: November 11, 2015
Last sequence update: November 11, 2015
Last modified: December 20, 2017
This is version 10 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported