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Protein

DnaA regulatory inactivator Hda

Gene

hda

Organism
Xenorhabdus khoisanae
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA.UniRule annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA replication inhibitorUniRule annotationSAAS annotation, Initiation factorImported
Biological processDNA replicationUniRule annotationSAAS annotation, Protein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
DnaA regulatory inactivator HdaUniRule annotationSAAS annotation
Gene namesi
Name:hdaUniRule annotation
ORF Names:AB204_12640Imported
OrganismiXenorhabdus khoisanaeImported
Taxonomic identifieri880157 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesMorganellaceaeXenorhabdus
Proteomesi
  • UP000036277 Componenti: Unassembled WGS sequence

Interactioni

Subunit structurei

The active form seems to be an ADP-bound monomer. Forms the RIDA complex (regulatory inactivation of DnaA) of ATP-DnaA, ADP-Hda and the DNA-loaded beta sliding clamp (dnaN).UniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini18 – 213Bac_DnaAInterPro annotationAdd BLAST196

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili196 – 216Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the DnaA family. HdA subfamily.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

HAMAPiMF_01158 Hda, 1 hit
InterProiView protein in InterPro
IPR020591 Chromosome_initiator_DnaA-like
IPR013317 DnaA
IPR017788 Hda
IPR022864 Hda_Enterobact
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00308 Bac_DnaA, 1 hit
PRINTSiPR00051 DNAA
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR03420 DnaA_homol_Hda, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0J5FR34-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLLNTPSQLS LPLYLPDDET FASFFAGENT SLLAAIKLAI SQSHGSYIYF
60 70 80 90 100
WSRDGGGKSH LLHAACAELS QQEEAVGYVP LDKRAYFVPE VLDGMEHLSL
110 120 130 140 150
VCIDNIECIA GDQEWEMAIF NLYNRIVEIG RTCLLITGDR PPRQINLTLP
160 170 180 190 200
DLASRLDWGQ IYKLQPLSDD EKIQALQLRA KLRGFELPED VGRFVLKRLD
210 220 230
REMQTLFKTL DELDRASIVA QRKLTIPFVK DILEL
Length:235
Mass (Da):26,655
Last modified:October 14, 2015 - v1
Checksum:iFFD4E4C77831A27D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LFCV01000080 Genomic DNA Translation: KMJ44728.1
RefSeqiWP_047963722.1, NZ_LFCV01000080.1

Genome annotation databases

EnsemblBacteriaiKMJ44728; KMJ44728; AB204_12640
PATRICifig|880157.4.peg.2701

Similar proteinsi

Entry informationi

Entry nameiA0A0J5FR34_9GAMM
AccessioniPrimary (citable) accession number: A0A0J5FR34
Entry historyiIntegrated into UniProtKB/TrEMBL: October 14, 2015
Last sequence update: October 14, 2015
Last modified: December 20, 2017
This is version 19 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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