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Protein

Deoxyribose-phosphate aldolase

Gene

deoC

Organism
Enterobacter cloacae
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.UniRule annotationSAAS annotation

Catalytic activityi

2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde.UniRule annotationSAAS annotation

Pathwayi: 2-deoxy-D-ribose 1-phosphate degradation

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate.UniRule annotationSAAS annotation
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Deoxyribose-phosphate aldolase (deoC), Deoxyribose-phosphate aldolase (deoC), Deoxyribose-phosphate aldolase (deoC), Deoxyribose-phosphate aldolase (deoC), Deoxyribose-phosphate aldolase (deoC), Deoxyribose-phosphate aldolase (deoC), Deoxyribose-phosphate aldolase (deoC), Deoxyribose-phosphate aldolase (deoC), Deoxyribose-phosphate aldolase (deoC), Deoxyribose-phosphate aldolase (deoC), Deoxyribose-phosphate aldolase (deoC), Deoxyribose-phosphate aldolase (deoC), Deoxyribose-phosphate aldolase (deoC), Deoxyribose-phosphate aldolase (deoC), Deoxyribose-phosphate aldolase (deoC), Deoxyribose-phosphate aldolase (deoC), Deoxyribose-phosphate aldolase (deoC), Deoxyribose-phosphate aldolase (deoC), Deoxyribose-phosphate aldolase (deoC), Deoxyribose-phosphate aldolase (deoC), Deoxyribose-phosphate aldolase (deoC)
This subpathway is part of the pathway 2-deoxy-D-ribose 1-phosphate degradation, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate, the pathway 2-deoxy-D-ribose 1-phosphate degradation and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei102Proton donor/acceptorUniRule annotation1
Active sitei167Schiff-base intermediate with acetaldehydeUniRule annotation1
Active sitei201Proton donor/acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotationImported
LigandSchiff baseUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00002; UER00468

Names & Taxonomyi

Protein namesi
Recommended name:
Deoxyribose-phosphate aldolaseUniRule annotation (EC:4.1.2.4UniRule annotation)
Short name:
DERAUniRule annotation
Alternative name(s):
2-deoxy-D-ribose 5-phosphate aldolaseUniRule annotation
PhosphodeoxyriboaldolaseUniRule annotation
Short name:
DeoxyriboaldolaseUniRule annotation
Gene namesi
Name:deoCUniRule annotationImported
ORF Names:SAMEA2273187_01973Imported, TN43_09710Imported
OrganismiEnterobacter cloacaeImported
Taxonomic identifieri550 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEnterobacterEnterobacter cloacae complex
Proteomesi
  • UP000077295 Componenti: Unassembled WGS sequence
  • UP000032353 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.UniRule annotationSAAS annotation

Family and domain databases

CDDicd00959 DeoC, 1 hit
Gene3Di3.20.20.70, 1 hit
HAMAPiMF_00592 DeoC_type2, 1 hit
InterProiView protein in InterPro
IPR013785 Aldolase_TIM
IPR011343 DeoC
IPR002915 DeoC/FbaB/lacD_aldolase
IPR023649 DeoC_typeII
PANTHERiPTHR10889 PTHR10889, 1 hit
PfamiView protein in Pfam
PF01791 DeoC, 1 hit
PIRSFiPIRSF001357 DeoC, 1 hit
SMARTiView protein in SMART
SM01133 DeoC, 1 hit
TIGRFAMsiTIGR00126 deoC, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0J0H5K3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDLTASSLR ALKLMDLTTL NDDDTNEKVI ALCHQAKTPV GNTAAVCIYP
60 70 80 90 100
RFIPIARKTL KEQGTPEVRI ATVTNFPHGN DDIEIALAET RAAIAYGADE
110 120 130 140 150
VDVVFPYRAL IAGNEQVGFD LVKACKDACA AANVLLKVII ETGELKEEAL
160 170 180 190 200
IRKASEISIK AGADFIKTST GKVPVNATPE SARIMMEVIR DMGVSKTVGF
210 220 230 240 250
KPAGGVRTAE DAQQFLAIAD ELFGADWADS RHYRFGASSL LASLLKALGH

GDGKSASSY
Length:259
Mass (Da):27,658
Last modified:October 14, 2015 - v1
Checksum:i15F2441223315699
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JYGA02000001 Genomic DNA Translation: KJC01214.1
FKEV01000005 Genomic DNA Translation: SAE16337.1

Genome annotation databases

EnsemblBacteriaiCZW98997; CZW98997; SAMEA2273362_00829
KJC01214; KJC01214; TN43_09710
SAE16337; SAE16337; SAMEA2273187_01973

Similar proteinsi

Entry informationi

Entry nameiA0A0J0H5K3_ENTCL
AccessioniPrimary (citable) accession number: A0A0J0H5K3
Entry historyiIntegrated into UniProtKB/TrEMBL: October 14, 2015
Last sequence update: October 14, 2015
Last modified: November 22, 2017
This is version 21 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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