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Protein

Acetylornithine deacetylase

Gene

argE

Organism
Vibrio cholerae
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

N2-acetyl-L-ornithine + H2O = acetate + L-ornithine.SAAS annotation

Cofactori

Protein has several cofactor binding sites:
  • Co2+SAAS annotation
  • Zn2+SAAS annotation
  • glutathioneSAAS annotation

Pathwayi: L-arginine biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes L-ornithine from N(2)-acetyl-L-ornithine (linear).SAAS annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Acetylornithine deacetylase (argE), Acetylornithine deacetylase (argE), Acetylornithine deacetylase (argE), Acetylornithine deacetylase (argE), Acetylornithine deacetylase (argE), Acetylornithine deacetylase (argE), Acetylornithine deacetylase (argE), Acetylornithine deacetylase (argE), Acetylornithine deacetylase (argE), Acetylornithine deacetylase (argE), Acetylornithine deacetylase (argE), Acetylornithine deacetylase (argE)
This subpathway is part of the pathway L-arginine biosynthesis, which is itself part of Amino-acid biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes L-ornithine from N(2)-acetyl-L-ornithine (linear), the pathway L-arginine biosynthesis and in Amino-acid biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseSAAS annotationImported
Biological processAmino-acid biosynthesis, Arginine biosynthesisSAAS annotation
LigandCobaltSAAS annotation, Metal-bindingSAAS annotation, ZincSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00068; UER00110

Names & Taxonomyi

Protein namesi
Recommended name:
Acetylornithine deacetylaseSAAS annotation (EC:3.5.1.16SAAS annotation)
Gene namesi
Name:argEImported
ORF Names:ERS013140_03276Imported
OrganismiVibrio choleraeImported
Taxonomic identifieri666 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
Proteomesi
  • UP000045183 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Interactioni

Subunit structurei

Homodimer.SAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini66 – 177M20_dimerInterPro annotationAdd BLAST112

Sequence similaritiesi

Belongs to the peptidase M20A family. ArgE subfamily.SAAS annotation

Family and domain databases

CDDicd03894 M20_ArgE, 1 hit
InterProiView protein in InterPro
IPR010169 AcOrn-deacetyl
IPR036264 Bact_exopeptidase_dim_dom
IPR002933 Peptidase_M20
IPR011650 Peptidase_M20_dimer
PANTHERiPTHR43808:SF1 PTHR43808:SF1, 1 hit
PfamiView protein in Pfam
PF07687 M20_dimer, 1 hit
PF01546 Peptidase_M20, 1 hit
SUPFAMiSSF55031 SSF55031, 1 hit
TIGRFAMsiTIGR01892 AcOrn-deacetyl, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0H7AFG4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKGFFAFIYE AVKNVDWSKQ TKPLYVLATC DEETTMLGAR HFTENAPFKP
60 70 80 90 100
DYCIIGEPTS LVPIRAHKGH VANAIRVTGK SGHSSNPALG VNAIEIMHEV
110 120 130 140 150
LFALMQLRDR LIKEYHHPGF EIPTPTLNLG HIHGGDSPNR ICGCCELHYD
160 170 180 190 200
VRPLPGISLD GLDNLMHDAL REVQQKWPGR IELVPLHDPI PGYECAHDHP
210 220 230 240 250
FIHGISEICE QEAQTVNYCT EAPFLQQVCP TLVLGPGSID QAHQPDEFLA
260 270
FEFIDPTVRV LSRAMQKYCF
Length:270
Mass (Da):30,260
Last modified:October 14, 2015 - v1
Checksum:iB435AD1C9811D454
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CWRE01000146 Genomic DNA Translation: CSD38000.1

Genome annotation databases

EnsemblBacteriaiCSD38000; CSD38000; ERS013140_03276

Similar proteinsi

Entry informationi

Entry nameiA0A0H7AFG4_VIBCL
AccessioniPrimary (citable) accession number: A0A0H7AFG4
Entry historyiIntegrated into UniProtKB/TrEMBL: October 14, 2015
Last sequence update: October 14, 2015
Last modified: November 22, 2017
This is version 18 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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