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Protein
Submitted name:

Dihydrofolate reductase

Gene

folA_2

Organism
Mycoplasma pneumoniae (strain ATCC 15531 / DSM 22911 / NBRC 14401 / NCTC 10119 / FH)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
Dihydrofolate reductaseImported (EC:1.5.1.3Imported)
Gene namesi
Name:folA_2Imported
Ordered Locus Names:MPNE_0374Imported
OrganismiMycoplasma pneumoniae (strain ATCC 15531 / DSM 22911 / NBRC 14401 / NCTC 10119 / FH)Imported
Taxonomic identifieri722438 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
Proteomesi
  • UP000007756 Componenti: Chromosome

PTM / Processingi

Proteomic databases

PaxDbiA0A0H3DKL6.

Interactioni

Protein-protein interaction databases

STRINGi722438.MPNE_0374.

Structurei

3D structure databases

ProteinModelPortaliA0A0H3DKL6.
SMRiA0A0H3DKL6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 160DHFRInterPro annotationAdd BLAST160

Sequence similaritiesi

Belongs to the dihydrofolate reductase family.UniRule annotation

Phylogenomic databases

KOiK00287.
OMAiEECFVIG.

Family and domain databases

CDDicd00209. DHFR. 1 hit.
Gene3Di3.40.430.10. 1 hit.
InterProiView protein in InterPro
IPR012259. DHFR.
IPR024072. DHFR-like_dom_sf.
IPR017925. DHFR_CS.
IPR001796. DHFR_dom.
PANTHERiPTHR22778:SF16. PTHR22778:SF16. 1 hit.
PfamiView protein in Pfam
PF00186. DHFR_1. 1 hit.
SUPFAMiSSF53597. SSF53597. 1 hit.
PROSITEiView protein in PROSITE
PS00075. DHFR_1. 1 hit.
PS51330. DHFR_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A0H3DKL6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVKAIWAMDQ NGLIGNGNSL PWRIKAELQH FRQTTLHQDV LMGSATYLSL
60 70 80 90 100
PPVFSERNVY ILTRNLNFNP PDKGCLTKVI HEYENFIQPY LHHPDKHLYI
110 120 130 140 150
CGGAQVYEQL IPRCDALIVS TIFGKYTGDK YLKVDFSPFE LTKEISFAEF
160
KVAYYHKIAR
Length:160
Mass (Da):18,511
Last modified:September 16, 2015 - v1
Checksum:i87C323433A3FABA4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002077 Genomic DNA. Translation: ADK86789.1.
RefSeqiWP_010874677.1. NZ_CP010546.1.

Genome annotation databases

EnsemblBacteriaiADK86789; ADK86789; MPNE_0374.
KEGGimpj:MPNE_0374.
PATRICifig|722438.3.peg.359.

Similar proteinsi

Entry informationi

Entry nameiA0A0H3DKL6_MYCPB
AccessioniPrimary (citable) accession number: A0A0H3DKL6
Entry historyiIntegrated into UniProtKB/TrEMBL: September 16, 2015
Last sequence update: September 16, 2015
Last modified: March 28, 2018
This is version 19 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported