Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

CDP-diacylglycerol pyrophosphatase

Gene

cdh

Organism
Escherichia coli O1:K1 / APEC
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

CDP-diacylglycerol + H2O = CMP + phosphatidate.UniRule annotation

Pathwayi: CDP-diacylglycerol degradation

This protein is involved in step 1 of the subpathway that synthesizes phosphatidate from CDP-diacylglycerol.UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. CDP-diacylglycerol pyrophosphatase (cdh)
This subpathway is part of the pathway CDP-diacylglycerol degradation, which is itself part of Phospholipid metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes phosphatidate from CDP-diacylglycerol, the pathway CDP-diacylglycerol degradation and in Phospholipid metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotation
Biological processLipid biosynthesis, Lipid metabolism, Phospholipid biosynthesisUniRule annotation, Phospholipid metabolism

Enzyme and pathway databases

UniPathwayiUPA00609; UER00664

Names & Taxonomyi

Protein namesi
Recommended name:
CDP-diacylglycerol pyrophosphataseUniRule annotation (EC:3.6.1.26UniRule annotation)
Alternative name(s):
CDP-diacylglycerol phosphatidylhydrolaseUniRule annotation
CDP-diglyceride hydrolaseUniRule annotation
Gene namesi
Name:cdhUniRule annotationImported
ORF Names:APECO1_2551Imported
OrganismiEscherichia coli O1:K1 / APECImported
Taxonomic identifieri405955 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000008216 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Single-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei67 – 87HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membraneUniRule annotation, Cell membrane, Membrane

Structurei

3D structure databases

ProteinModelPortaliA0A0H2Z4H8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Cdh family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

KOiK01521
OMAiSPFIMLA

Family and domain databases

Gene3Di3.30.428.30, 1 hit
HAMAPiMF_00319 Cdh, 1 hit
InterProiView protein in InterPro
IPR003763 CDP-diacylglyc_Pase
IPR015993 CDP-diacylglyc_Pase_proteobac
IPR038433 CDP-diacylglyc_Pase_sf
IPR036265 HIT-like_sf
PfamiView protein in Pfam
PF02611 CDH, 1 hit
SUPFAMiSSF54197 SSF54197, 1 hit
TIGRFAMsiTIGR00672 cdh, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0H2Z4H8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSSAAGRKR KKSILLTAVR SIRSANADFP RIIIKPGGFS PLGFLFVTIL
60 70 80 90 100
RYPCISLRYR EKKMKKAGLL FLVMIVIAVV ATGIGYWKLT GEESDTLRKI
110 120 130 140 150
VLEQCLPNQQ ENQNPSPCAE VKPNAGYVVL KDRHGPLQYL LMPTYRINGT
160 170 180 190 200
ESPLLTDPST PNFFWLAWQA RDFMSQKYGQ PVPDRAVSLA INSRTGRTQN
210 220 230 240 250
HFHIHISCIR PDVREQLDNN LANISSRWLP LPGGLRGHEY LARRVTESEL
260 270 280 290 300
VQRSPFMMLA EEVPEAREHM GSYGLAMVRQ SDNSFVLLAT QRNLLTLNRA
310
SAEEIQDHQC EILR
Length:314
Mass (Da):35,586
Last modified:September 16, 2015 - v1
Checksum:i45D65E4D6E81D136
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000468 Genomic DNA Translation: ABJ03384.1

Genome annotation databases

EnsemblBacteriaiABJ03384; ABJ03384; APECO1_2551
KEGGiecv:APECO1_2551

Similar proteinsi

Entry informationi

Entry nameiA0A0H2Z4H8_ECOK1
AccessioniPrimary (citable) accession number: A0A0H2Z4H8
Entry historyiIntegrated into UniProtKB/TrEMBL: September 16, 2015
Last sequence update: September 16, 2015
Last modified: March 28, 2018
This is version 13 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health