Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Latent-transforming growth factor beta-binding protein 2

Gene

Ltbp2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

Enzyme and pathway databases

ReactomeiR-RNO-2129379 Molecules associated with elastic fibres

Names & Taxonomyi

Protein namesi
Submitted name:
Latent-transforming growth factor beta-binding protein 2Imported
Gene namesi
Name:Ltbp2Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 6

Organism-specific databases

RGDi68380 Ltbp2

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 35Sequence analysisAdd BLAST35
ChainiPRO_500254688336 – 1767Sequence analysisAdd BLAST1732

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi185 ↔ 195PROSITE-ProRule annotation
Disulfide bondi203 ↔ 212PROSITE-ProRule annotation
Disulfide bondi387 ↔ 397PROSITE-ProRule annotation
Disulfide bondi405 ↔ 414PROSITE-ProRule annotation
Disulfide bondi1478 ↔ 1488PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSRNOG00000012094
ExpressionAtlasiA0A0G2KAU7 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini181 – 213EGF-likeInterPro annotationAdd BLAST33
Domaini383 – 415EGF-likeInterPro annotationAdd BLAST33
Domaini538 – 581TBInterPro annotationAdd BLAST44
Domaini608 – 648EGF-likeInterPro annotationAdd BLAST41
Domaini658 – 710TBInterPro annotationAdd BLAST53
Domaini834 – 876EGF-likeInterPro annotationAdd BLAST43
Domaini877 – 919EGF-likeInterPro annotationAdd BLAST43
Domaini920 – 959EGF-likeInterPro annotationAdd BLAST40
Domaini1000 – 1040EGF-likeInterPro annotationAdd BLAST41
Domaini1125 – 1165EGF-likeInterPro annotationAdd BLAST41
Domaini1166 – 1207EGF-likeInterPro annotationAdd BLAST42
Domaini1208 – 1248EGF-likeInterPro annotationAdd BLAST41
Domaini1249 – 1290EGF-likeInterPro annotationAdd BLAST42
Domaini1357 – 1409TBInterPro annotationAdd BLAST53
Domaini1431 – 1473EGF-likeInterPro annotationAdd BLAST43
Domaini1474 – 1513EGF-likeInterPro annotationAdd BLAST40
Domaini1530 – 1582TBInterPro annotationAdd BLAST53
Domaini1679 – 1715EGF-likeInterPro annotationAdd BLAST37
Domaini1720 – 1764EGF-likeInterPro annotationAdd BLAST45

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotationSAAS annotation, RepeatSAAS annotation, SignalSequence analysis

Phylogenomic databases

GeneTreeiENSGT00760000118806

Family and domain databases

Gene3Di3.90.290.10, 4 hits
InterProiView protein in InterPro
IPR001881 EGF-like_Ca-bd_dom
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR000152 EGF-type_Asp/Asn_hydroxyl_site
IPR018097 EGF_Ca-bd_CS
IPR009030 Growth_fac_rcpt_cys_sf
IPR017878 TB_dom
IPR036773 TB_dom_sf
PfamiView protein in Pfam
PF00008 EGF, 2 hits
PF07645 EGF_CA, 14 hits
PF12661 hEGF, 1 hit
PF00683 TB, 4 hits
SMARTiView protein in SMART
SM00181 EGF, 19 hits
SM00179 EGF_CA, 17 hits
SUPFAMiSSF57184 SSF57184, 4 hits
SSF57581 SSF57581, 5 hits
PROSITEiView protein in PROSITE
PS00010 ASX_HYDROXYL, 11 hits
PS00022 EGF_1, 2 hits
PS01186 EGF_2, 10 hits
PS50026 EGF_3, 15 hits
PS01187 EGF_CA, 5 hits
PS51364 TB, 4 hits

Sequencei

Sequence statusi: Complete.

A0A0G2KAU7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRAPTTVRCS GRIQRARWRG FLPLVLALLM GTSHAQRDSV GRYEPASRDA
60 70 80 90 100
NRLWRPVGNH PAAAAAKVYS LFREPDAPVP GLSPSEWNQP GQGIPGRLAE
110 120 130 140 150
AEARRPSRAQ QLRRVQSPVQ TRRSNPRGQQ PPAARTAHSV VRLATPQRPA
160 170 180 190 200
AARRGRLTGR NVCGGQCCPG WTTSNSTNHC IKPVCQPPCQ NRGSCSRPQL
210 220 230 240 250
CICRSGFRGA RCEEVIPEEE FDPQNARPVP RRSVEGAPGP HRSSEARGSL
260 270 280 290 300
VTRIQPLPPP LPPPPSRTLS QTRPLQQHAG LSRTVRRYPA TGTNGQLMSN
310 320 330 340 350
ALPSGPGPEL RDSSQQAAHM NHLSHPWGLN LTEKIKKIKV VFTPTICKQT
360 370 380 390 400
CARGRCANSC EKGDTTTLYS QGGHGHDPKS GFRIYFCQIP CLNGGRCIGR
410 420 430 440 450
DECWCPANST GKFCHLPVPQ PDREPPGRGS QHRALLEGPL KQSTFTLPLS
460 470 480 490 500
NQLASVNPSL VKVQIHHPPE ASVQIHQVAR VRGEVDPVPE DNSVETRASH
510 520 530 540 550
RPHGSSGHSH WASNSIPARA GEAPRPPPVP SRHYGLLGQC YLSTVNGQCA
560 570 580 590 600
NPLGELTSQE DCCGSVGTFW GVTSCAPCPP RPAFPVIENG QLECPQGYKR
610 620 630 640 650
LNLSHCQDIN ECLTLGLCKD SECVNTRGSY LCTCRPGLML DPSRSRCVSD
660 670 680 690 700
KAVSMKQGLC YRSLVSGTCT LPLVQRITKQ ICCCSRVGKA WGSKCEHCPL
710 720 730 740 750
PGTEAFREIC PAGHGYAYSS SDIRLSMRKA EEEELASPVR EQRQQSSGPP
760 770 780 790 800
PGAAERQPLR AATATWIEAE TLPDKGDSRA IQITTSAPHL PARVPGDATG
810 820 830 840 850
RPTPSLPGQG IPEGPAEEQV IPSSDVLVTH GPPGFDPCFA GASNICGPGT
860 870 880 890 900
CVKLPNGYRC VCSPGYQLHP SQDYCTDDNE CLRNPCEGRG RCVNSVGSYS
910 920 930 940 950
CLCYPGYTLA TLGDTQECQD VDECEQPGVC SGGRCSNTEG SYHCECDQGY
960 970 980 990 1000
VMVRRGHCQD INECRHPGTC PDGRCVNSPG SYTCLACEEG YIGQSGNCVD
1010 1020 1030 1040 1050
MNECLTPGIC AHGRCINMEG SFRCSCEPGY ELTPDKKGCR DVDECASRAS
1060 1070 1080 1090 1100
CPTGLCLNTE GSFTCSACQS GYWVNEDGTA CEDLDECAFP GVCPTGVCTN
1110 1120 1130 1140 1150
TVGSFSCKDC DRGFRPSPLG NSCEDVDECE GPQNSCLGGE CKNTDGSYQC
1160 1170 1180 1190 1200
LCPQGFQLAN GTVCEDVDEC VGEEHCAPHG ECLNSPGSFF CLCAPGFASA
1210 1220 1230 1240 1250
EGGTRCQDVD ECATTEPCLG GHCVNTEGSF NCLCETGFQP APDSGECVDI
1260 1270 1280 1290 1300
DECANDTVCG NHGFCDNTDG SFRCLCDQGF ETSPSGWECV DVNECELMLA
1310 1320 1330 1340 1350
VCGDALCENV EGSFLCLCAS DLEEYDAEEG HCRPRVAGAQ RIPEVPTEEQ
1360 1370 1380 1390 1400
AAGLTGMECY AEHNGGPPCS QILGQNSTQA ECCCTQGARW GETCDPCPSE
1410 1420 1430 1440 1450
DSVEFSELCP SGQGYIPVEG AWTFGQAMYT DADECILFGP ALCQNGRCLN
1460 1470 1480 1490 1500
TVPGYICLCN PGYHYDAVSR KCQDHNECQD LACENGECVN TEGSFHCFCS
1510 1520 1530 1540 1550
PPLILDLSGQ RCVNSTSSSE DFPDHDIHMD ICWKKVTNDV CSQPLRGHHT
1560 1570 1580 1590 1600
TYTECCCQDG EAWSQQCALC PPRSSEVYAQ LCNVARIEAE REAGIHFRPG
1610 1620 1630 1640 1650
YEYGPGPDDL PETLYGPDGA PFYNYLGPED TVPEPPFSNT ASHLGDNTPI
1660 1670 1680 1690 1700
LEPPLQPSEL QPTISPAIQE PLASFEGLQA EECGILNGCE NGRCVRVREG
1710 1720 1730 1740 1750
YTCDCFEGFQ LDTALMACVD VNECEDLNGP AALCAHGHCE NTEGSYRCHC
1760
SPGYVAEPGP PHCAAKE
Length:1,767
Mass (Da):190,143
Last modified:July 22, 2015 - v1
Checksum:i7195CA185EA5554C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC113727 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSRNOT00000077458; ENSRNOP00000075533; ENSRNOG00000012094

Similar proteinsi

Entry informationi

Entry nameiA0A0G2KAU7_RAT
AccessioniPrimary (citable) accession number: A0A0G2KAU7
Entry historyiIntegrated into UniProtKB/TrEMBL: July 22, 2015
Last sequence update: July 22, 2015
Last modified: March 28, 2018
This is version 21 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health