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Protein

Adenosine receptor A3

Gene

Adora3

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Recommended name:
Adenosine receptor A3UniRule annotation
Gene namesi
Name:Adora3Imported
Synonyms:LOC100363178Imported, LOC100911796Imported, Tmigd3Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 2

Organism-specific databases

RGDi2051 Adora3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 38HelicalUniRule annotationAdd BLAST27
Transmembranei50 – 74HelicalUniRule annotationAdd BLAST25
Transmembranei80 – 108HelicalUniRule annotationAdd BLAST29
Transmembranei129 – 151HelicalUniRule annotationAdd BLAST23
Transmembranei180 – 206HelicalUniRule annotationAdd BLAST27
Transmembranei234 – 257HelicalUniRule annotationAdd BLAST24
Transmembranei263 – 285HelicalUniRule annotationAdd BLAST23

Keywords - Cellular componenti

Cell membraneUniRule annotation, Membrane

PTM / Processingi

Keywords - PTMi

Disulfide bondUniRule annotation, GlycoproteinUniRule annotation

Expressioni

Gene expression databases

BgeeiENSRNOG00000050743

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini31 – 284G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST254

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

GeneTreeiENSGT00550000074524

Family and domain databases

InterProiView protein in InterPro
IPR000466 Adeno_A3_rcpt
IPR001634 Adenosn_rcpt
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00555 ADENOSINEA3R
PR00424 ADENOSINER
PR00237 GPCRRHODOPSN
SMARTiView protein in SMART
SM01381 7TM_GPCR_Srsx, 1 hit
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0G2JZ55-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKANNTTTSA LWLQITYITM EAAIGLCAVV GNMLVIWVVK LNRTLRTTTF
60 70 80 90 100
YFIVSLALAD IAVGVLVIPL AIAVSLEVQM HFYACLFMSC VLLVFTHASI
110 120 130 140 150
MSLLAIAVDR YLRVKLTVRY RTVTTQRRIW LFLGLCWLVS FLVGLTPMFG
160 170 180 190 200
WNRKVTLELS QNSSTLSCHF RSVVGLDYMV FFSFITWILI PLVVMCIIYL
210 220 230 240 250
DIFYIIRNKL SQNLTGFRET RAFYGREFKT AKSLFLVLFL FALCWLPLSI
260 270 280 290 300
INFVSYFNVK IPEIAMCLGI LLSHANSMMN PIVYACKKKV QRNYFVILRA
310
CRLCQTSDSL DSNLEQTTE
Length:319
Mass (Da):36,508
Last modified:July 22, 2015 - v1
Checksum:i4A8621011AE42B10
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07012777 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSRNOT00000082943; ENSRNOP00000070915; ENSRNOG00000050743

Similar proteinsi

Entry informationi

Entry nameiA0A0G2JZ55_RAT
AccessioniPrimary (citable) accession number: A0A0G2JZ55
Entry historyiIntegrated into UniProtKB/TrEMBL: July 22, 2015
Last sequence update: July 22, 2015
Last modified: March 28, 2018
This is version 11 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported