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Protein
Submitted name:

Signal peptide peptidase-like 2C

Gene

SPPL2C

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Signal peptide peptidase-like 2CImported
Gene namesi
Name:SPPL2CImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

HGNCiHGNC:28902. SPPL2C.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei185 – 207HelicalSequence analysisAdd BLAST23
Transmembranei251 – 274HelicalSequence analysisAdd BLAST24
Transmembranei280 – 304HelicalSequence analysisAdd BLAST25
Transmembranei316 – 341HelicalSequence analysisAdd BLAST26
Transmembranei377 – 396HelicalSequence analysisAdd BLAST20
Transmembranei441 – 459HelicalSequence analysisAdd BLAST19
Transmembranei471 – 494HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_500254639122 – 684Sequence analysisAdd BLAST663

Proteomic databases

PeptideAtlasiA0A0G2JPF3.

Structurei

3D structure databases

ProteinModelPortaliA0A0G2JPF3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

OrthoDBiEOG091G05NG.

Family and domain databases

InterProiView protein in InterPro
IPR007369. Peptidase_A22B_SPP.
IPR006639. Preselin/SPP.
IPR033150. SPPL2C.
PANTHERiPTHR12174. PTHR12174. 1 hit.
PTHR12174:SF38. PTHR12174:SF38. 1 hit.
PfamiView protein in Pfam
PF04258. Peptidase_A22B. 1 hit.
SMARTiView protein in SMART
SM00730. PSN. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A0G2JPF3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MACLGFLLPV GFLLLISTVA GGKYGVAHVV SENWSKDYCI LFSSDYITLP
60 70 80 90 100
RDLHHAPLLP LYDGTKAPWC PGEDSPHQAQ LRSPSQRPLR QTTAMVMRGN
110 120 130 140 150
CSFHTKGWLA QGQGAHGLLI VSRVSDQQCS DTTLAPQDPR QPLADLTIPV
160 170 180 190 200
AMLHYADMLD ILSHTRGEAV VRVAMYAPPE PIIDYNMLVI FILAVGTVAA
210 220 230 240 250
GGYWAGLTEA NRLQRRRARR GGGSGGHHQL QEAAAAEGAQ KEDNEDIPVD
260 270 280 290 300
FTPAMTGVVV TLSCSLMLLL YFFYDHFVYV TIGIFGLGAG IGLYSCLSPL
310 320 330 340 350
VCHLSLRQYQ RPPHSLWASL PLPLLLLASL CATVIIFWVA YRNEDRWAWL
360 370 380 390 400
LQDTLGISYC LFVLHRVRLP TLKNCSSFLL ALLAFDVFFV FVTPFFTKTG
410 420 430 440 450
ESIMAQVALG PAESSSHERL PMVLKVPRLR VSALTLCSQP FSILGFGDIV
460 470 480 490 500
VPGFLVAYCC RFDVQVCSRQ IYFVACTVAY AVGLLVTFMA MVLMQMGQPA
510 520 530 540 550
LLYLVSSTLL TSLAVAACRQ ELSLFWTGQG RAKMCGLGCA PSAGSRQKQE
560 570 580 590 600
GAADAHTAST LERGTSRGAG DLDSNPGEDT TEIVTISENE ATNPEDRSDS
610 620 630 640 650
SEGWSDAHLD PNELPFIPPG ASEELMPLMP MAMLIPLMPL MPPPSELGHV
660 670 680
HAQAQAHETG LPWAGLHKRK GLKVRKSMST QAPL
Length:684
Mass (Da):74,484
Last modified:July 22, 2015 - v1
Checksum:iD5889C6921159E08
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC243621 Genomic DNA. No translation available.
UniGeneiHs.144491.

Genome annotation databases

EnsembliENST00000621383; ENSP00000483514; ENSG00000277106.

Similar proteinsi

Entry informationi

Entry nameiA0A0G2JPF3_HUMAN
AccessioniPrimary (citable) accession number: A0A0G2JPF3
Entry historyiIntegrated into UniProtKB/TrEMBL: July 22, 2015
Last sequence update: July 22, 2015
Last modified: October 25, 2017
This is version 15 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported