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Protein

Chromosomal replication initiator protein DnaA

Gene

dnaA

Organism
Parcubacteria group bacterium GW2011_GWA2_40_37
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.UniRule annotationSAAS annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi163 – 170ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation
Biological processDNA replicationUniRule annotationSAAS annotation
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chromosomal replication initiator protein DnaAUniRule annotationSAAS annotation
Gene namesi
Name:dnaAUniRule annotation
ORF Names:UU01_C0009G0011Imported
OrganismiParcubacteria group bacterium GW2011_GWA2_40_37Imported
Taxonomic identifieri1618817 [NCBI]
Taxonomic lineageiBacteriaunclassified Parcubacteria group
Proteomesi
  • UP000034813 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini155 – 289AAAInterPro annotationAdd BLAST135
Domaini365 – 434Bac_DnaA_CInterPro annotationAdd BLAST70

Sequence similaritiesi

Belongs to the DnaA family.UniRule annotationSAAS annotation

Family and domain databases

CDDicd06571. Bac_DnaA_C. 1 hit.
Gene3Di1.10.1750.10. 1 hit.
HAMAPiMF_00377. DnaA_bact. 1 hit.
InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR001957. Chromosome_initiator_DnaA.
IPR020591. Chromosome_initiator_DnaA-like.
IPR018312. Chromosome_initiator_DnaA_CS.
IPR013317. DnaA.
IPR013159. DnaA_C.
IPR024633. DnaA_N_dom.
IPR027417. P-loop_NTPase.
IPR010921. Trp_repressor/repl_initiator.
PANTHERiPTHR30050:SF2. PTHR30050:SF2. 1 hit.
PfamiView protein in Pfam
PF00308. Bac_DnaA. 1 hit.
PF08299. Bac_DnaA_C. 1 hit.
PF11638. DnaA_N. 1 hit.
PRINTSiPR00051. DNAA.
SMARTiView protein in SMART
SM00382. AAA. 1 hit.
SM00760. Bac_DnaA_C. 1 hit.
SUPFAMiSSF48295. SSF48295. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00362. DnaA. 1 hit.
PROSITEiView protein in PROSITE
PS01008. DNAA. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A0G0SIQ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESMSTNTKQ LWKNCLSEIE AGISKANFCT WFKNTSIVRE DMGIIYIGVP
60 70 80 90 100
NEFVRDWLMN KYHKLITKII ADSYENMRAV EYTITKVEAA KEMERVEAPV
110 120 130 140 150
ESGNYINKEL PLRDLYINPE DNLNPRYHFN SFIVGAFNEL AYAASLAIID
160 170 180 190 200
SPGTKYNPFF IYGGTGLGKT HLIQAVGNLI KDKYPNKKVH YMTLEKFATD
210 220 230 240 250
FINSLQSNKA NSFKEKYRKY DLLIIDDIQF IGKMEKIQEE LFHTFNTFHE
260 270 280 290 300
NNKQIIFSSD KHPNYIPELA DRLKSRFAAG MIVDISPPEY ESRLAILKVK
310 320 330 340 350
LRELNVALDQ EILEYVAASV DGNIRELEGS MNTLVCQYRL KNKTLTLAEV
360 370 380 390 400
KNLLKNNMRP KKNMAIKDIV KTVSEYYKLE ESSVYEKTRK KEIVKARQIV
410 420 430 440 450
MYLLREDFNV SYPLIGQKLG GKDHTTVIHS CIKIKNDLKS DPQLLQELDQ

IRIMFK
Length:456
Mass (Da):52,832
Last modified:July 22, 2015 - v1
Checksum:i2A6DB44DC922E370
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LBYZ01000009 Genomic DNA. Translation: KKR62256.1.

Genome annotation databases

EnsemblBacteriaiKKR62256; KKR62256; UU01_C0009G0011.
PATRICifig|1618817.3.peg.448.

Similar proteinsi

Entry informationi

Entry nameiA0A0G0SIQ3_9BACT
AccessioniPrimary (citable) accession number: A0A0G0SIQ3
Entry historyiIntegrated into UniProtKB/TrEMBL: July 22, 2015
Last sequence update: July 22, 2015
Last modified: October 25, 2017
This is version 17 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported