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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Methanosarcina mazei (Methanosarcina frisia)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetaseUniRule annotationImported, Ligase
Biological processProtein biosynthesisUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
ORF Names:DU44_03640Imported, DU48_19925Imported, DU63_09530Imported, DU65_13055Imported, DU74_04790Imported
OrganismiMethanosarcina mazei (Methanosarcina frisia)Imported
Taxonomic identifieri2209 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosarcina
Proteomesi
  • UP000033987 Componenti: Unassembled WGS sequence
  • UP000034733 Componenti: Unassembled WGS sequence
  • UP000034001 Componenti: Unassembled WGS sequence
  • UP000034450 Componenti: Unassembled WGS sequence
  • UP000034064 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 88Arg_tRNA_synt_NInterPro annotationAdd BLAST82
Domaini449 – 569DALR_1InterPro annotationAdd BLAST121

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi123 – 133"HIGH" regionUniRule annotationAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0F8S2T6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFLELKAQAT SILKEAIRKA GFEVEDSELQ FETSPHADLA SRAAFRLAGI
60 70 80 90 100
HRQNPKDLAS RIVSAVEIPE GSFIGKVSAA GPYINFFAGR HYLNGTVNAV
110 120 130 140 150
LKEKEKFGCG APKDRILLEH TSANPNGPLH VGHIRNSIIG DTLARILRRA
160 170 180 190 200
GYDVEVQYYV NDMGRQIAVV SWACERFELD LSRKSDSAIA DVYIKANVEL
210 220 230 240 250
DKNPEYVKEI DALMEKVEAG DVRTIEHFDK AVSLAVAGIK ETLLRLNVAH
260 270 280 290 300
DKFVSESTFL KSGAVHDIVE RIKATGRTKT DKGALVVDLS DYGFEKTLVI
310 320 330 340 350
QRSNGTSLYT TRDLAYHEWK TGQADRIIDV FGADHKLISG QLRATLNTIG
360 370 380 390 400
VKEPEVVIFE FVSLPEGSMS TRRGQFISAD DLFDRVTGAA FEQVETRRPE
410 420 430 440 450
TSYEFKKQVA EAVGLGAVRY DIVRVSPEKS TVFNWKEALD FEKQGAPYIQ
460 470 480 490 500
YSHARACSIL EKAKEEAAWN PDKEIDPSLL VEDSEIDLIK KMAMFDSVID
510 520 530 540 550
LGARELKPHV LAIYARELAD AFNQFYRFVP VIAAEDENVR AARLALVDCA
560
RVVLANSLDT LGIIAPESM
Length:569
Mass (Da):63,201
Last modified:July 22, 2015 - v1
Checksum:i8E1D086444AEB668
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JJPO01000112 Genomic DNA Translation: KKG71692.1
JJQC01000113 Genomic DNA Translation: KKH19601.1
JJQA01000012 Genomic DNA Translation: KKH20479.1
JJQB01000048 Genomic DNA Translation: KKH21408.1
JJQN01000059 Genomic DNA Translation: KKH61156.1
RefSeqiWP_015411753.1, NZ_JJQN01000059.1

Genome annotation databases

EnsemblBacteriaiKKG71692; KKG71692; DU63_09530
KKH19601; KKH19601; DU65_13055
KKH20479; KKH20479; DU44_03640
KKH21408; KKH21408; DU48_19925
KKH61156; KKH61156; DU74_04790
GeneIDi24853053
PATRICifig|2209.43.peg.2074

Similar proteinsi

Entry informationi

Entry nameiA0A0F8S2T6_METMZ
AccessioniPrimary (citable) accession number: A0A0F8S2T6
Entry historyiIntegrated into UniProtKB/TrEMBL: July 22, 2015
Last sequence update: July 22, 2015
Last modified: March 28, 2018
This is version 18 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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