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Protein

Chromosomal replication initiator protein DnaA

Gene

dnaA

Organism
Spongiibacter sp. IMCC21906
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.UniRule annotationSAAS annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi222 – 229ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation
Biological processDNA replicationUniRule annotationSAAS annotation
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chromosomal replication initiator protein DnaAUniRule annotationSAAS annotation
Gene namesi
Name:dnaAUniRule annotation
ORF Names:IMCC21906_00430Imported
OrganismiSpongiibacter sp. IMCC21906Imported
Taxonomic identifieri1620392 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaCellvibrionalesSpongiibacteraceaeSpongiibacter
Proteomesi
  • UP000035013 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini214 – 405AAAInterPro annotationAdd BLAST192
Domaini425 – 494Bac_DnaA_CInterPro annotationAdd BLAST70

Sequence similaritiesi

Belongs to the DnaA family.UniRule annotationSAAS annotation

Phylogenomic databases

KOiK02313.

Family and domain databases

CDDicd06571. Bac_DnaA_C. 1 hit.
Gene3Di1.10.1750.10. 1 hit.
HAMAPiMF_00377. DnaA_bact. 1 hit.
InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR001957. Chromosome_initiator_DnaA.
IPR020591. Chromosome_initiator_DnaA-like.
IPR018312. Chromosome_initiator_DnaA_CS.
IPR013317. DnaA.
IPR013159. DnaA_C.
IPR024633. DnaA_N_dom.
IPR027417. P-loop_NTPase.
IPR010921. Trp_repressor/repl_initiator.
PANTHERiPTHR30050:SF2. PTHR30050:SF2. 1 hit.
PfamiView protein in Pfam
PF00308. Bac_DnaA. 1 hit.
PF08299. Bac_DnaA_C. 1 hit.
PF11638. DnaA_N. 1 hit.
PRINTSiPR00051. DNAA.
SMARTiView protein in SMART
SM00382. AAA. 1 hit.
SM00760. Bac_DnaA_C. 1 hit.
SUPFAMiSSF48295. SSF48295. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00362. DnaA. 1 hit.
PROSITEiView protein in PROSITE
PS01008. DNAA. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A0F7M1H7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEATWQKCV AHLRDELPSQ QFNTWIKPLR FDAQEGRIDL IAPNRFVRDW
60 70 80 90 100
VSDRFLERIL ELVAELAPAD SRPEVALGVG QRNLQTGAAT VGSMRVASTS
110 120 130 140 150
SSPLEPSGVL SSSSINNKFS IGSSSLPQSE DDSRQDFVSD AAASPAAAQE
160 170 180 190 200
SPELPGMQLR GNGSGGRRSV EVEGRIRHQS SLMEAYTFET FVEGKSNQLA
210 220 230 240 250
RAAASQIAEN PGKAYNPLFL YGGVGLGKTH LMHAVGNALL AQNPNAKVVY
260 270 280 290 300
LHSERFVADM VKALQLNAIN EFKRYYRSVD ALLIDDIQFF SGKERSQEEF
310 320 330 340 350
FHTFNALLEG GQQMILTCDR YPKEIKGLEE RLKSRFGWGL TVAVEPPELE
360 370 380 390 400
TRVAILLKKA EQEKITLPSD AAFFIAQRVR SNVRELEGVL KRVIASSRFM
410 420 430 440 450
AKPIDVPLIK DSLKDLLALQ DKLVSLENIQ RTAAEYYKIK ISDLMSKRRS
460 470 480 490 500
RSVARPRQVA MALSKELTNH SLPEIGESFG GRDHTTVLHA CKKIKELRES
510
DGDIREDYQN LIRLLTT
Length:517
Mass (Da):57,589
Last modified:July 22, 2015 - v1
Checksum:i8240EB73CA590F82
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP011477 Genomic DNA. Translation: AKH68123.1.

Genome annotation databases

EnsemblBacteriaiAKH68123; AKH68123; IMCC21906_00430.
KEGGispoi:IMCC21906_00430.
PATRICifig|1620392.3.peg.472.

Similar proteinsi

Entry informationi

Entry nameiA0A0F7M1H7_9GAMM
AccessioniPrimary (citable) accession number: A0A0F7M1H7
Entry historyiIntegrated into UniProtKB/TrEMBL: July 22, 2015
Last sequence update: July 22, 2015
Last modified: October 25, 2017
This is version 17 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported