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Protein

Nicotinate phosphoribosyltransferase

Gene

pncB

Organism
Photorhabdus temperata subsp. thracensis
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.UniRule annotationSAAS annotation

Catalytic activityi

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate.UniRule annotationSAAS annotation

Pathwayi: NAD(+) biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes nicotinate D-ribonucleotide from nicotinate.UniRule annotationSAAS annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Nicotinate phosphoribosyltransferase (pncB)
This subpathway is part of the pathway NAD(+) biosynthesis, which is itself part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes nicotinate D-ribonucleotide from nicotinate, the pathway NAD(+) biosynthesis and in Cofactor biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseImported, LigaseUniRule annotationSAAS annotationImported, Transferase
Biological processPyridine nucleotide biosynthesisUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00253; UER00457.

Names & Taxonomyi

Protein namesi
Recommended name:
Nicotinate phosphoribosyltransferaseUniRule annotationSAAS annotation (EC:6.3.4.21UniRule annotationSAAS annotation)
Short name:
NAPRTaseUniRule annotation
Gene namesi
Name:pncBUniRule annotation
ORF Names:VY86_22170Imported
OrganismiPhotorhabdus temperata subsp. thracensisImported
Taxonomic identifieri230089 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesMorganellaceaePhotorhabdus
Proteomesi
  • UP000034866 Componenti: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the NAPRTase family.UniRule annotationSAAS annotation

Phylogenomic databases

KOiK00763.

Family and domain databases

HAMAPiMF_00570. NAPRTase. 1 hit.
InterProiView protein in InterPro
IPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR036068. Nicotinate_pribotase_like_C.
PANTHERiPTHR11098. PTHR11098. 1 hit.
PfamiView protein in Pfam
PF04095. NAPRTase. 1 hit.
PIRSFiPIRSF000484. NAPRT. 1 hit.
SUPFAMiSSF51690. SSF51690. 1 hit.
TIGRFAMsiTIGR01514. NAPRTase. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A0F7LUP3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLDATPIIK SLLDTDAYKL HMQQAVYHHY SHMPVVAEFR CRGDELLGEY
60 70 80 90 100
AKELRHQVNM MADLALTDAE FNYLSSLPFF KADYLDWFKT FRFNPQQVNI
110 120 130 140 150
SVTDSGQLAI RISGLWHEVI MWEVPLLALL SELVHRYHPL DNAAENAVNQ
160 170 180 190 200
LRKLIKLFYQ DAENEGIDLS GFKLMDFGTR RRFSHSVQHA IVSELQQNFP
210 220 230 240 250
YLIGTSNYQL AQQLGISPVG TQAHEWFQAH QQISPELASS QREALQSWLN
260 270 280 290 300
EYPNQLGIAL TDCITMDAFL RDFDAQFANR YQGLRHDSGD PIEWGEKAIA
310 320 330 340 350
HYQKLGIDPL TKTLVFSDSL DFQKALALYR HFHNRINLIF GIGTRLTCNI
360 370 380 390 400
PGVKPLNIVI KLVECNGKPV AKLSDSPGKT ICEDNEFVNR LRAAFDIPQV

KQAC
Length:404
Mass (Da):46,127
Last modified:July 22, 2015 - v1
Checksum:i12FCCCC479ADDAB7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP011104 Genomic DNA. Translation: AKH65653.1.
RefSeqiWP_046976592.1. NZ_CP011104.1.

Genome annotation databases

EnsemblBacteriaiAKH65653; AKH65653; VY86_22170.
GeneIDi29598885.
KEGGiptt:VY86_22170.
PATRICifig|230089.6.peg.5017.

Similar proteinsi

Entry informationi

Entry nameiA0A0F7LUP3_PHOTE
AccessioniPrimary (citable) accession number: A0A0F7LUP3
Entry historyiIntegrated into UniProtKB/TrEMBL: July 22, 2015
Last sequence update: July 22, 2015
Last modified: October 25, 2017
This is version 17 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported