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Protein

Phosphoglycolate phosphatase

Gene

gph

Organism
Salmonella enterica I
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

2-phosphoglycolate + H2O = glycolate + phosphate.UniRule annotationSAAS annotation

Cofactori

Protein has several cofactor binding sites:
  • Mg2+UniRule annotationSAAS annotation
  • chlorideUniRule annotation

Pathwayi: glycolate biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes glycolate from 2-phosphoglycolate.UniRule annotationSAAS annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Phosphoglycolate phosphatase (LFZ50_13640), Phosphoglycolate phosphatase (AO411_2018250), Phosphoglycolate phosphatase (gph)
This subpathway is part of the pathway glycolate biosynthesis, which is itself part of Organic acid metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes glycolate from 2-phosphoglycolate, the pathway glycolate biosynthesis and in Organic acid metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei13NucleophileUniRule annotation1
Metal bindingi13MagnesiumUniRule annotation1
Metal bindingi15MagnesiumUniRule annotation1
Metal bindingi192MagnesiumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotation
Biological processCarbohydrate metabolismUniRule annotationSAAS annotation
LigandChlorideUniRule annotation, MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00865; UER00834

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycolate phosphataseUniRule annotation (EC:3.1.3.18UniRule annotation)
Short name:
PGPUniRule annotation
Short name:
PGPaseUniRule annotation
Gene namesi
Name:gphImported
ORF Names:CVR97_05360Imported, SE14_03697Imported
OrganismiSalmonella enterica IImported
Taxonomic identifieri59201 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000034636 Componenti: Chromosome
  • UP000228538 Componenti: Unassembled WGS sequence

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

SMRiA0A0F7JCI3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.SAAS annotation

Family and domain databases

Gene3Di1.10.150.2401 hit
3.40.50.10002 hits
HAMAPiMF_00495 GPH_hydrolase_bact, 1 hit
InterProiView protein in InterPro
IPR036412 HAD-like_sf
IPR006439 HAD-SF_hydro_IA
IPR023214 HAD_sf
IPR023198 PGP-like_dom2
IPR006346 PGPase/MupP
IPR037512 PGPase_prok
PRINTSiPR00413 HADHALOGNASE
SUPFAMiSSF56784 SSF56784, 1 hit
TIGRFAMsiTIGR01549 HAD-SF-IA-v1, 1 hit
TIGR01509 HAD-SF-IA-v3, 1 hit
TIGR01449 PGP_bact, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0F7JCI3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDKLQNIRGV AFDLDGTLVD SAPGLAAAVD MALYALELPV AGEERVITWI
60 70 80 90 100
GNGADVLMER ALTWAREERA TLRKTMGKPP VDEDIPAEEQ VRILRKLFDR
110 120 130 140 150
YYGEVAEEGT VLFPHVADTL GALHASGLSL GLVTNKPTPF VAPLLESLDI
160 170 180 190 200
AKYFSVVIGG DDVQNKKPHP EPLLLVASRL GMMPEQMLFV GDSRNDIQAA
210 220 230 240 250
KAAGCPSVGL TYGYNYGEAI ALSEPDVIYD SFNDLLPALG LPHSDNQEIK

ND
Length:252
Mass (Da):27,303
Last modified:July 22, 2015 - v1
Checksum:i1216F19E6D086B97
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP011428 Genomic DNA Translation: AKH09113.1
PHGX01000020 Genomic DNA Translation: PJH62832.1
RefSeqiWP_000359655.1, NZ_PHGX01000020.1

Genome annotation databases

EnsemblBacteriaiAKH09113; AKH09113; SE14_03697
OCS96492; OCS96492; A7B05_20350
OCS99868; OCS99868; A7B04_08840
PATRICifig|59201.158.peg.3766

Similar proteinsi

Entry informationi

Entry nameiA0A0F7JCI3_SALET
AccessioniPrimary (citable) accession number: A0A0F7JCI3
Entry historyiIntegrated into UniProtKB/TrEMBL: July 22, 2015
Last sequence update: July 22, 2015
Last modified: March 28, 2018
This is version 26 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported