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Protein

Ribonuclease P protein component

Gene

rnpA

Organism
Escherichia coli O157:H7 str. SS52
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.UniRule annotationSAAS annotation

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonucleaseUniRule annotationSAAS annotation, Hydrolase, Nuclease, RNA-bindingUniRule annotationSAAS annotation
Biological processtRNA processingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein componentUniRule annotationSAAS annotation (EC:3.1.26.5UniRule annotationSAAS annotation)
Short name:
RNase P proteinUniRule annotation
Short name:
RNaseP proteinUniRule annotation
Alternative name(s):
Protein C5UniRule annotation
Gene namesi
Name:rnpAUniRule annotation
ORF Names:SS52_5001Imported
OrganismiEscherichia coli O157:H7 str. SS52Imported
Taxonomic identifieri1330457 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000030908 Componenti: Chromosome

Interactioni

Subunit structurei

Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.UniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliA0A0F6FEG6.
SMRiA0A0F6FEG6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili51 – 71Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the RnpA family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

OMAiLHQHELP.

Family and domain databases

Gene3Di3.30.230.10. 1 hit.
HAMAPiMF_00227. RNase_P. 1 hit.
InterProiView protein in InterPro
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR000100. RNase_P.
IPR020539. RNase_P_CS.
PANTHERiPTHR33992. PTHR33992. 1 hit.
PfamiView protein in Pfam
PF00825. Ribonuclease_P. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD003629. Ribonuclease_P. 1 hit.
SUPFAMiSSF54211. SSF54211. 1 hit.
TIGRFAMsiTIGR00188. rnpA. 1 hit.
PROSITEiView protein in PROSITE
PS00648. RIBONUCLEASE_P. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A0F6FEG6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVKLAFPREL RLLTPSQFTF VFQQPQRAGT PQITILGRLN SLGHPRIGLT
60 70 80 90 100
VAKKNVRRAH ERNRIKRLTR ESFRLRQHEL PAMDFVVVAK KGVANLDNRA
110
LSEALEKLWR RHCRLARGS
Length:119
Mass (Da):13,788
Last modified:June 24, 2015 - v1
Checksum:i4E3D34DACA1C6240
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP010304 Genomic DNA. Translation: AJA28806.1.
RefSeqiWP_000239733.1. NZ_CP010304.1.

Genome annotation databases

EnsemblBacteriaiAJA28806; AJA28806; SS52_5001.

Similar proteinsi

Entry informationi

Entry nameiA0A0F6FEG6_ECO57
AccessioniPrimary (citable) accession number: A0A0F6FEG6
Entry historyiIntegrated into UniProtKB/TrEMBL: June 24, 2015
Last sequence update: June 24, 2015
Last modified: March 28, 2018
This is version 17 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported