Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Cytochrome c oxidase subunit 1

Gene

CO1

Organism
Polypedilum sp. 'nubifer_lookalike'
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.UniRule annotation

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.UniRule annotation

Pathwayi: oxidative phosphorylation

This protein is involved in the pathway oxidative phosphorylation, which is part of Energy metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway oxidative phosphorylation and in Energy metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
Biological processElectron transport, Respiratory chainUniRule annotation, Transport
LigandCopperUniRule annotation, HemeUniRule annotation, Iron, Metal-binding

Enzyme and pathway databases

UniPathwayiUPA00705.

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 1UniRule annotation (EC:1.9.3.1UniRule annotation)
Gene namesi
Name:CO1Imported
Encoded oniMitochondrionImported
OrganismiPolypedilum sp. 'nubifer_lookalike'Imported
Taxonomic identifieri1636521 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraNematoceraChironomoideaChironomidaeChironominaePolypedilumunclassified Polypedilum

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei14 – 40HelicalSequence analysisAdd BLAST27
Transmembranei52 – 79HelicalSequence analysisAdd BLAST28

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membraneUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 104COX1InterPro annotationAdd BLAST104

Sequence similaritiesi

Belongs to the heme-copper respiratory oxidase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

Gene3Di1.20.210.10. 1 hit.
InterProiView protein in InterPro
IPR023616. Cyt_c_oxase-like_su1_dom.
IPR000883. Cyt_C_Oxase_1.
PANTHERiPTHR10422. PTHR10422. 1 hit.
PfamiView protein in Pfam
PF00115. COX1. 1 hit.
PRINTSiPR01165. CYCOXIDASEI.
SUPFAMiSSF81442. SSF81442. 1 hit.
PROSITEiView protein in PROSITE
PS50855. COX1. 1 hit.

Sequencei

Sequence statusi: Fragment.

A0A0E3JK99-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
LSSSIAHSGA SVDLAIFSLH LAGVSSILGS VNFITTVINM RSNGITLDRM
60 70 80 90 100
PLFVWSIVIT TVLLLLSLPV LAGAITMLLT DRNLNTSFFD PAGGGDPILY

QHLF
Length:104
Mass (Da):11,043
Last modified:June 24, 2015 - v1
Checksum:i24D6A2F8015980E6
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei104Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KP461699 Genomic DNA. Translation: AKA62220.1.
KP461700 Genomic DNA. Translation: AKA62221.1.
KP461701 Genomic DNA. Translation: AKA62222.1.
KP461702 Genomic DNA. Translation: AKA62223.1.
KP461703 Genomic DNA. Translation: AKA62224.1.
KP461704 Genomic DNA. Translation: AKA62225.1.
KP461705 Genomic DNA. Translation: AKA62226.1.
KP461706 Genomic DNA. Translation: AKA62227.1.
KP461707 Genomic DNA. Translation: AKA62228.1.
KP461708 Genomic DNA. Translation: AKA62229.1.
KP461709 Genomic DNA. Translation: AKA62230.1.
KP461710 Genomic DNA. Translation: AKA62231.1.
KP461711 Genomic DNA. Translation: AKA62232.1.
KP461712 Genomic DNA. Translation: AKA62233.1.
KP461713 Genomic DNA. Translation: AKA62234.1.
KP461714 Genomic DNA. Translation: AKA62235.1.
KP461715 Genomic DNA. Translation: AKA62236.1.
KP461716 Genomic DNA. Translation: AKA62237.1.
KP461717 Genomic DNA. Translation: AKA62238.1.
KP461718 Genomic DNA. Translation: AKA62239.1.
KP461719 Genomic DNA. Translation: AKA62240.1.
KP461720 Genomic DNA. Translation: AKA62241.1.
KP461721 Genomic DNA. Translation: AKA62242.1.
KP461722 Genomic DNA. Translation: AKA62243.1.
KP461723 Genomic DNA. Translation: AKA62244.1.
KP461862 Genomic DNA. Translation: AKA62383.1.
KP461863 Genomic DNA. Translation: AKA62384.1.
KP461864 Genomic DNA. Translation: AKA62385.1.
KP462186 Genomic DNA. Translation: AKA62707.1.
KP462225 Genomic DNA. Translation: AKA62746.1.
KP462226 Genomic DNA. Translation: AKA62747.1.
KP462227 Genomic DNA. Translation: AKA62748.1.
KP462228 Genomic DNA. Translation: AKA62749.1.
KP462229 Genomic DNA. Translation: AKA62750.1.
KP462230 Genomic DNA. Translation: AKA62751.1.
KP462231 Genomic DNA. Translation: AKA62752.1.
KP462232 Genomic DNA. Translation: AKA62753.1.
KP462233 Genomic DNA. Translation: AKA62754.1.
KP462234 Genomic DNA. Translation: AKA62755.1.
KP462235 Genomic DNA. Translation: AKA62756.1.
KP462236 Genomic DNA. Translation: AKA62757.1.
KP462237 Genomic DNA. Translation: AKA62758.1.
KP462238 Genomic DNA. Translation: AKA62759.1.
KP462239 Genomic DNA. Translation: AKA62760.1.
KP462240 Genomic DNA. Translation: AKA62761.1.
KP462241 Genomic DNA. Translation: AKA62762.1.
KP462242 Genomic DNA. Translation: AKA62763.1.
KP462243 Genomic DNA. Translation: AKA62764.1.
KP462244 Genomic DNA. Translation: AKA62765.1.
KP462245 Genomic DNA. Translation: AKA62766.1.
KP462246 Genomic DNA. Translation: AKA62767.1.
KP462247 Genomic DNA. Translation: AKA62768.1.
KP462248 Genomic DNA. Translation: AKA62769.1.
KP462249 Genomic DNA. Translation: AKA62770.1.
KP462250 Genomic DNA. Translation: AKA62771.1.
KP462251 Genomic DNA. Translation: AKA62772.1.
KP462252 Genomic DNA. Translation: AKA62773.1.
KP462253 Genomic DNA. Translation: AKA62774.1.
KP462254 Genomic DNA. Translation: AKA62775.1.
KP462255 Genomic DNA. Translation: AKA62776.1.
KP462256 Genomic DNA. Translation: AKA62777.1.
KP462257 Genomic DNA. Translation: AKA62778.1.
KP462258 Genomic DNA. Translation: AKA62779.1.
KP462259 Genomic DNA. Translation: AKA62780.1.
KP462260 Genomic DNA. Translation: AKA62781.1.
KP462261 Genomic DNA. Translation: AKA62782.1.
KP462262 Genomic DNA. Translation: AKA62783.1.
KP462263 Genomic DNA. Translation: AKA62784.1.
KP462264 Genomic DNA. Translation: AKA62785.1.
KP462265 Genomic DNA. Translation: AKA62786.1.
KP462266 Genomic DNA. Translation: AKA62787.1.
KP462267 Genomic DNA. Translation: AKA62788.1.
KP462268 Genomic DNA. Translation: AKA62789.1.
KP462269 Genomic DNA. Translation: AKA62790.1.
KP462270 Genomic DNA. Translation: AKA62791.1.
KP462271 Genomic DNA. Translation: AKA62792.1.
KP462272 Genomic DNA. Translation: AKA62793.1.
KP462273 Genomic DNA. Translation: AKA62794.1.
KP462274 Genomic DNA. Translation: AKA62795.1.
KP462275 Genomic DNA. Translation: AKA62796.1.
KP462276 Genomic DNA. Translation: AKA62797.1.
KP462277 Genomic DNA. Translation: AKA62798.1.
KP462278 Genomic DNA. Translation: AKA62799.1.
KP462279 Genomic DNA. Translation: AKA62800.1.
KP462280 Genomic DNA. Translation: AKA62801.1.
KP462281 Genomic DNA. Translation: AKA62802.1.
KP462282 Genomic DNA. Translation: AKA62803.1.
KP462283 Genomic DNA. Translation: AKA62804.1.
KP462284 Genomic DNA. Translation: AKA62805.1.
KP462285 Genomic DNA. Translation: AKA62806.1.
KP462286 Genomic DNA. Translation: AKA62807.1.
KP462287 Genomic DNA. Translation: AKA62808.1.
KP462288 Genomic DNA. Translation: AKA62809.1.
KP462289 Genomic DNA. Translation: AKA62810.1.
KP462290 Genomic DNA. Translation: AKA62811.1.
KP462291 Genomic DNA. Translation: AKA62812.1.
KP462292 Genomic DNA. Translation: AKA62813.1.
KP462293 Genomic DNA. Translation: AKA62814.1.
KP462294 Genomic DNA. Translation: AKA62815.1.
KP462295 Genomic DNA. Translation: AKA62816.1.
KP462296 Genomic DNA. Translation: AKA62817.1.
KP462297 Genomic DNA. Translation: AKA62818.1.
KP462298 Genomic DNA. Translation: AKA62819.1.
KP462299 Genomic DNA. Translation: AKA62820.1.
KP462300 Genomic DNA. Translation: AKA62821.1.
KP462301 Genomic DNA. Translation: AKA62822.1.
KP462302 Genomic DNA. Translation: AKA62823.1.
KP462303 Genomic DNA. Translation: AKA62824.1.
KP462304 Genomic DNA. Translation: AKA62825.1.
KP462305 Genomic DNA. Translation: AKA62826.1.
KP462306 Genomic DNA. Translation: AKA62827.1.
KP462307 Genomic DNA. Translation: AKA62828.1.
KP462308 Genomic DNA. Translation: AKA62829.1.
KP462309 Genomic DNA. Translation: AKA62830.1.
KP462310 Genomic DNA. Translation: AKA62831.1.
KP462311 Genomic DNA. Translation: AKA62832.1.
KP462312 Genomic DNA. Translation: AKA62833.1.
KP462313 Genomic DNA. Translation: AKA62834.1.
KP462314 Genomic DNA. Translation: AKA62835.1.
KP462315 Genomic DNA. Translation: AKA62836.1.
KP462316 Genomic DNA. Translation: AKA62837.1.
KP462317 Genomic DNA. Translation: AKA62838.1.
KP462318 Genomic DNA. Translation: AKA62839.1.
KP462319 Genomic DNA. Translation: AKA62840.1.
KP462320 Genomic DNA. Translation: AKA62841.1.
KP462321 Genomic DNA. Translation: AKA62842.1.
KP462322 Genomic DNA. Translation: AKA62843.1.
KP462323 Genomic DNA. Translation: AKA62844.1.
KP462324 Genomic DNA. Translation: AKA62845.1.
KP462325 Genomic DNA. Translation: AKA62846.1.
KP462326 Genomic DNA. Translation: AKA62847.1.
KP462327 Genomic DNA. Translation: AKA62848.1.
KP462328 Genomic DNA. Translation: AKA62849.1.
KP462329 Genomic DNA. Translation: AKA62850.1.
KP462330 Genomic DNA. Translation: AKA62851.1.
KP462331 Genomic DNA. Translation: AKA62852.1.
KP462332 Genomic DNA. Translation: AKA62853.1.
KP462333 Genomic DNA. Translation: AKA62854.1.
KP462334 Genomic DNA. Translation: AKA62855.1.
KP462335 Genomic DNA. Translation: AKA62856.1.
KP462336 Genomic DNA. Translation: AKA62857.1.
KP462337 Genomic DNA. Translation: AKA62858.1.
KP462338 Genomic DNA. Translation: AKA62859.1.
KP462339 Genomic DNA. Translation: AKA62860.1.
KP462340 Genomic DNA. Translation: AKA62861.1.
KP462341 Genomic DNA. Translation: AKA62862.1.
KP462342 Genomic DNA. Translation: AKA62863.1.
KP462343 Genomic DNA. Translation: AKA62864.1.
KP462344 Genomic DNA. Translation: AKA62865.1.
KP462345 Genomic DNA. Translation: AKA62866.1.
KP462346 Genomic DNA. Translation: AKA62867.1.
KP462347 Genomic DNA. Translation: AKA62868.1.
KP462348 Genomic DNA. Translation: AKA62869.1.
KP462349 Genomic DNA. Translation: AKA62870.1.
KP462350 Genomic DNA. Translation: AKA62871.1.
KP462351 Genomic DNA. Translation: AKA62872.1.
KP462352 Genomic DNA. Translation: AKA62873.1.
KP462353 Genomic DNA. Translation: AKA62874.1.
KP462354 Genomic DNA. Translation: AKA62875.1.
KP462355 Genomic DNA. Translation: AKA62876.1.
KP462356 Genomic DNA. Translation: AKA62877.1.
KP462357 Genomic DNA. Translation: AKA62878.1.
KP462385 Genomic DNA. Translation: AKA62906.1.
KP462445 Genomic DNA. Translation: AKA62966.1.
KP462446 Genomic DNA. Translation: AKA62967.1.
KP462447 Genomic DNA. Translation: AKA62968.1.
KP462448 Genomic DNA. Translation: AKA62969.1.
KP462449 Genomic DNA. Translation: AKA62970.1.
KP462450 Genomic DNA. Translation: AKA62971.1.
KP462451 Genomic DNA. Translation: AKA62972.1.
KP462685 Genomic DNA. Translation: AKA63206.1.

Similar proteinsi

Entry informationi

Entry nameiA0A0E3JK99_9DIPT
AccessioniPrimary (citable) accession number: A0A0E3JK99
Entry historyiIntegrated into UniProtKB/TrEMBL: June 24, 2015
Last sequence update: June 24, 2015
Last modified: May 10, 2017
This is version 11 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)