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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Francisella tularensis
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetaseUniRule annotation, Ligase
Biological processProtein biosynthesisUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotationImported
ORF Names:AV531_03030Imported, DR86_1159Imported
OrganismiFrancisella tularensisImported
Taxonomic identifieri263 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesFrancisellaceaeFrancisella
Proteomesi
  • UP000185477 Componenti: Chromosome
  • UP000029018 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliA0A0E3A6B6.
SMRiA0A0E3A6B6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 86Arg_tRNA_synt_NInterPro annotationAdd BLAST86
Domaini459 – 581DALR_1InterPro annotationAdd BLAST123

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi122 – 132"HIGH" regionUniRule annotationAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR036695. Arg-tRNA-synth_N_sf.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A0E3A6B6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIENYLSET LAKVFQKLGY AESFAKVVTS TREDVRHFQC NGAMPLAKFA
60 70 80 90 100
KKPPLAIAEE IVEHIDAEDI FAKLEVAKPG FINITLAPKF LADTTNRFLN
110 120 130 140 150
SNKFGVQNNL PNRKVVLDFG GPNVAKPMHV GHIRSALLGD ALQRIHRFCG
160 170 180 190 200
DTVVSDVHLG DWGTQMGMLI EEIKLQSPQL VYFDENYTGE YPTESPVTVQ
210 220 230 240 250
ELAEIYPRAS KRCKSDINEM EKARLATFEL QQGRRGYVAL WQHFVRISID
260 270 280 290 300
AVKKDFDSLD VHFDLWLGES DANKFIDEMI SYFQANNFIY EDEGAWVIDT
310 320 330 340 350
NKDGVPPLIV IKKDGGVMYG TTDLATLWQR SKDLDPDEII YVVDKRQSLH
360 370 380 390 400
FKQVFSVAER TKVVSEKCKL KHVAFGTVNG KDGRPFKTRE GGVMHLADLI
410 420 430 440 450
SQAKEYAKNR MPDENDDSII NQIAMATIKF GDLINNYAND YFFDLEKFAQ
460 470 480 490 500
HEGKTGPYLL YTVVRAKSIL RKIFGDNYDI KSLAKDYKVV NAHNEYEEKL
510 520 530 540 550
QLQLIQFPIA VQRAYENSQP HHICEYAYSL ANSFNKFYVN CPINNLDDES
560 570 580
LKKARIALCM ATVKAMTIAS DLIGISIPER M
Length:581
Mass (Da):65,995
Last modified:May 27, 2015 - v1
Checksum:i4CBF10AAA5B6C004
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP013853 Genomic DNA. Translation: APS91825.1.
JOOV01000023 Genomic DNA. Translation: KFJ74945.1.
RefSeqiWP_003020254.1. NZ_NBTB01000001.1.

Genome annotation databases

EnsemblBacteriaiKFJ74945; KFJ74945; DR86_1159.
PATRICifig|263.84.peg.1480.

Similar proteinsi

Entry informationi

Entry nameiA0A0E3A6B6_FRATU
AccessioniPrimary (citable) accession number: A0A0E3A6B6
Entry historyiIntegrated into UniProtKB/TrEMBL: May 27, 2015
Last sequence update: May 27, 2015
Last modified: November 22, 2017
This is version 18 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported