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Protein

Thiamine pyrophosphokinase

Gene
N/A
Organism
Oryza rufipogon (Brownbeard rice) (Asian wild rice)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thiamine = AMP + thiamine diphosphate.UniRule annotation

Pathwayi: thiamine diphosphate biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes thiamine diphosphate from thiamine.UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Thiamine pyrophosphokinase, Thiamine pyrophosphokinase, Thiamine pyrophosphokinase
This subpathway is part of the pathway thiamine diphosphate biosynthesis, which is itself part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes thiamine diphosphate from thiamine, the pathway thiamine diphosphate biosynthesis and in Cofactor biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotation, Transferase
LigandATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00060; UER00597.

Names & Taxonomyi

Protein namesi
Recommended name:
Thiamine pyrophosphokinaseUniRule annotation (EC:2.7.6.2UniRule annotation)
OrganismiOryza rufipogon (Brownbeard rice) (Asian wild rice)Imported
Taxonomic identifieri4529 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
Proteomesi
  • UP000008022 Componenti: Unassembled WGS sequence

Structurei

3D structure databases

SMRiA0A0E0MW41.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini191 – 257TPK_B1_bindingInterPro annotationAdd BLAST67

Sequence similaritiesi

Belongs to the thiamine pyrophosphokinase family.UniRule annotation

Phylogenomic databases

OMAiESKMRFG.

Family and domain databases

CDDicd07995. TPK. 1 hit.
Gene3Di2.60.120.320. 1 hit.
3.40.50.10240. 1 hit.
InterProiView protein in InterPro
IPR006282. Thi_PPkinase.
IPR016966. Thiamin_pyrophosphokinase_euk.
IPR007373. Thiamin_PyroPKinase_B1-bd.
IPR036371. TPK_B1-bd_sf.
IPR007371. TPK_catalytic.
IPR036759. TPK_catalytic_sf.
PfamiView protein in Pfam
PF04265. TPK_B1_binding. 1 hit.
PF04263. TPK_catalytic. 1 hit.
PIRSFiPIRSF031057. Thiamin_pyrophosphokinase. 1 hit.
SMARTiView protein in SMART
SM00983. TPK_B1_binding. 1 hit.
SUPFAMiSSF63862. SSF63862. 1 hit.
SSF63999. SSF63999. 1 hit.
TIGRFAMsiTIGR01378. thi_PPkinase. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A0E0MW41-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLGRAIRSME VMVHSSTFLL PKLHQPANSP AKKYALVVLN QNLPRFVPRL
60 70 80 90 100
WTHAKLRICA DGGANRIFDE MFQMTNDPDY ESTRKRYIPE IIEGDMDSIR
110 120 130 140 150
PEVKQFYSSQ GSKISDKSHN QETTDLHKCI SRIHRCTPDH EKTNLCVLVT
160 170 180 190 200
GALGGRFDHE AANINILYLF SDMRIVLLSD DCLIRLLPKT HKHEIYIESS
210 220 230 240 250
VEGPHCGLFP VGAPSGSTTT TGLKWNLSEA KMRFGSMIST SNIVHAEKVT
260
VQSDADLLWT ISLRNLT
Length:267
Mass (Da):30,107
Last modified:May 27, 2015 - v1
Checksum:iA21BDF30C4C59073
GO

Genome annotation databases

EnsemblPlantsiORUFI01G16700.1; ORUFI01G16700.1; ORUFI01G16700.
GrameneiORUFI01G16700.1; ORUFI01G16700.1; ORUFI01G16700.

Similar proteinsi

Entry informationi

Entry nameiA0A0E0MW41_ORYRU
AccessioniPrimary (citable) accession number: A0A0E0MW41
Entry historyiIntegrated into UniProtKB/TrEMBL: May 27, 2015
Last sequence update: May 27, 2015
Last modified: November 22, 2017
This is version 13 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported